Zobrazeno 1 - 10
of 13
pro vyhledávání: '"M.J.S.T. Steenwinkel"'
Autor:
Robert A. Baan, Vassilis L. Souliotis, Soterios A. Kyrtopoulos, M.J.S.T. Steenwinkel, J.H.M. van Delft
Publikováno v:
Carcinogenesis. 19:731-739
Groups of lambda lacZ transgenic mice were treated i.p. with N-nitrosodimethylamine (NDMA) as single doses of 5 mg/kg or 10 mg/kg or as 10 daily doses of 1 mg/kg and changes in DNA N7- or O6-methylguanine or the repair enzyme O6-alkylguanine-DNA alky
Autor:
C. Valavanis, J.H.M. van Delft, Soterios A. Kyrtopoulos, Vasiliki Pletsa, M.J.S.T. Steenwinkel
Publikováno v:
Carcinogenesis. 18:2191-2196
The DNA damaging and mutagenic activities of procarbazine, a methylating drug employed in cancer chemotherapy and suspected of causing therapy-related leukaemia, were investigated in the liver and bone marrow of lambda lacZ transgenic mice (MutaMouse
Autor:
Robert A. Baan, M.J.S.T. Steenwinkel, A.A. van Zeeland, J.H.M. van Delft, A. de Groot, Manfred F. Rajewsky, G. Eberle-Adamkiewicz, Jürgen Thomale
Publikováno v:
Toxicological Sciences. 35:131-137
Determination of N7- and O6-methylguanine in Rat Liver DNA after Oral Exposure to Hydrazine by Use of Immunochemical and Electrochemical Detection Methods, VAN DELFT, J. H. M., STEENWINKEL, M-J. S. T., DE GROOT, A. T. L., VAN ZEELAND, A. A., EBERLE-A
Autor:
J. Stone, G. Rowley, Soterios A. Kyrtopoulos, R.C. Garner, Jane Cole, Peter B. Farmer, Franco Merlo, D. Beare, Robert A. Baan, K.S. Amaning, D.E.G. Shuker, Steinar Øvrebø, P. Van Hummelen, C. Leuratti, Herman Autrup, O. Sepai, J.H.M. van Delft, Åshild Andreassen, P.Sabro Nielsen, K.H. Dingley, M.J.S.T. Steenwinkel, Nikos Theodorakopoulos, Ad D. Tates, Nigel J. Jones, A. Ellul, Aage Haugen, K. Aldrich, A.B. Vestergård, A. Schouft, Angelo Abbondandolo, R. Lawrence, Micheline Kirsch-Volders, Adayapalam T. Natarajan, Naoum C. Bacalis, Alastair P.W. Waugh, Kemal Haque, Andrew C. Povey, Emily Capulas, P Castelain, Vassilis L. Souliotis, Raymond Waters
Publikováno v:
Farmer, P B, Sepai, O, Lawrence, R, Autrup, H, Nielsen, P S, Vestergård, A B, Waters, R, Leuratti, C, Jones, N J, Stone, J, Baan, R A, van Delft, J H M, Steenwinkel, M J S T, Kyrtopoulos, S A, Souliotis, V L, Theodorakopoulos, N, Bacalis, N C, Natarajan, A T, Tates, A D, Haugen, A, Andreassen, Å, Øvrebø, S, Shuker, D E G, Amaning, K S, Schouft, A, Ellul, A, Garner, R C, Dingley, K H, Abbondandolo, A, Merlo, F, Cole, J, Aldrich, K, Beare, D, Capulas, E, Rowley, G, Waugh, A P W, Povey, A C, Haque, K, Kirsch-Volders, M, Van Hummelen, P & Castelain, P 1996, ' Biomonitoring human exposure to environmental carcinogenic chemicals ', Mutagenesis, vol. 11, no. 4, pp. 363-381 .
A coordinated study was carried out on the development, evaluation and application of biomonitoring procedures for populations exposed to environmental genotoxic pollutants. The procedures used involved both direct measurement of DNA or protein damag
Publikováno v:
Carcinogenesis. 14:463-467
Hamster tracheal organ cultures were used to investigate the relationship between DNA adduct formation measured directly by the 32P-postlabeling assay, and the DNA damage measured indirectly by the unscheduled DNA synthesis (UDS) assay. Hamster trach
Autor:
M.J.S.T. Steenwinkel, J.H.M. van Delft, Vassiliki Pletsa, Soterios A. Kyrtopoulos, Robert A. Baan
Publikováno v:
Cancer Letters, 2, 146, 155-160
In order to examine the in vivo genotoxic activity of dichlorvos, λlacZ transgenic mice (Muta(TM)Mouse) were treated i.p. with single (4.4 or 11 mg/kg) or multiple (5x11 mg/kg) doses of this agent and sacrificed 4 h or 14 days post-treatment for DNA
Autor:
J.H.M. van Delft, Vassiliki Pletsa, M.J.S.T. Steenwinkel, Soterios A. Kyrtopoulos, Robert A. Baan
Publikováno v:
Cancer Letters, 135(1), 21-27. Elsevier Ireland Ltd
Cancer Letters 135:1(Jan1999):21-27
Cancer Letters, 135, 21-27
Cancer Letters, 1, 135, 21-27
Cancer Letters 135:1(Jan1999):21-27
Cancer Letters, 135, 21-27
Cancer Letters, 1, 135, 21-27
Laboratory of Chemical Carcinogenesis, Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Athens, Greece.Following single or multiple oral treatments of rats or lambda lacZ transgenic mice with methyl bromide,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496640fd41ea916063ad8e50913c4353
https://cris.maastrichtuniversity.nl/en/publications/3e98b1d5-5d44-4c5d-a680-12ab54330098
https://cris.maastrichtuniversity.nl/en/publications/3e98b1d5-5d44-4c5d-a680-12ab54330098
Publikováno v:
Mutation research. 360(2)
The recent introduction of the phenyl-beta-D-galactopyranoside (P-gal)-based positive-selection system for screening of lambda lacZ phages originating from the lambda lacZ transgenic mouse (Muta Mouse) has made the determination of mutant frequencies
Autor:
Robert A. Baan, M.J.S.T. Steenwinkel, J.G. van Asten, Hans Verhagen, C.J.M. Rompelberg, J.H.M. van Delft
Publikováno v:
Mutation Research-Genetic Toxicology, 1, 369, 87-96
To study the possible reduction by eugenol of the mutagenicity and genotoxicity of benzo[a]pyrene (B[a]P) in vivo, the lambda-lacZ-transgenic mouse strain 40.6 (Muta Mouse) was used. Male mice were fed a diet containing 0.4% (w/w) eugenol or a contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36891aa582fcebcd07f688dce14a79bf
http://resolver.tudelft.nl/uuid:bd305644-0948-4afa-a7ad-5bb75aa73def
http://resolver.tudelft.nl/uuid:bd305644-0948-4afa-a7ad-5bb75aa73def
Publikováno v:
Human and Experimental Toxicology, 13, 880-887
Polycyclic aromatic hydrocarbons (PAH) form a large group of organic chemicals that are widely distributed in our environment as pollutants of air, water and soil. Several PAH are carcinogenic in rodents, while exposure to these compounds has been as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbcb8dff552ec8a471f9f135610cf56
http://resolver.tudelft.nl/uuid:7bc269da-1b02-4d76-bf68-3c9e26db8fd0
http://resolver.tudelft.nl/uuid:7bc269da-1b02-4d76-bf68-3c9e26db8fd0