Výsledky vyhledávání - "M.J. de Groot"

Early Onset of Coronary Artery Calcification in Women With Previous Preeclampsia

Autor: Gerbrand A. Zoet, Maryam Kavousi, Cindy Meun, Arie Franx, Bart C.J.M. Fauser, Eric A.P. Steegers, Christianne M.J. de Groot, Johannes J. Duvekot, Laura Brouwers, Katie M. Linstra, Birgitta K. Velthuis, Eric Boersma, Laura Benschop, Bas B. van Rijn, Jeanine E. Roeters van Lennep, Ricardo P.J. Budde, Angela H.E.M. Maas, Yvonne T. van der Schouw

Publikováno v: Circulation-Cardiovascular Imaging, 13, 11
Circulation: Cardiovascular Imaging
Circulation Cardiovascular Imaging, 13(11):e010340. Lippincott Williams & Wilkins
Circulation-Cardiovascular Imaging, 13
Benschop, L, Brouwers, L, Zoet, G A, Meun, C, Boersma, E, Budde, R P J, Fauser, B C J M, De Groot, C M J, Van Der Schouw, Y T, Maas, A H E M, Velthuis, B K, Linstra, K M, Kavousi, M, Duvekot, J J, Franx, A, Steegers, E, Van Rijn, B B & Van Lennep, J E R 2020, ' Early Onset of Coronary Artery Calcification in Women with Previous Preeclampsia ', Circulation: Cardiovascular Imaging . https://doi.org/10.1161/CIRCIMAGING.119.010340

Background: Preeclampsia, coronary artery calcification (CAC), and atherosclerotic plaque are risk factors for the development of cardiovascular disease. We determined at what age CAC becomes apparent on coronary computed tomography after preeclampsi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d365c3d35442ba1af7c6257643a1c3f4
https://doi.org/10.1161/circimaging.119.010340

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Hydrogen atom abstraction of 3,5 disubstitued analogues of paracetemol by horseradish peroxidase and cytochrome P450

Autor: Nico P. E. Vermeulen, J. M. Te Koppele, M.J. de Groot, E.J. Baede, J.G.M. Bessems

Publikováno v: Xenobiotica, 28(9), 855-875. Informa Healthcare
Bessems, J G M, de Groot, M J, Baede, E J, te Koppele, J M & Vermeulen, N P E 1998, ' Hydrogen atom abstraction of 3,5 disubstitued analogues of paracetemol by horseradish peroxidase and cytochrome P450. ', Xenobiotica, vol. 28, no. 9, pp. 855-875 . https://doi.org/10.1080/004982598239100
Xenobiotica, 9, 28, 855-875

1. The formation of free radicals during enzyme catalysed oxidation of eight 3,5-disubstituted analogues of paracetamol (PAR) has been studied. A simple peroxidase system as well as cytochrome P450-containing systems were used. Radicals were detected

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1906b75345ad706c6111570d1e4fd5
https://research.vu.nl/en/publications/e6f8970a-9439-41c8-a812-ecedc554972a

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Structure-activity relationships for the glutathione conjugation of 2-substituted 1-chloro-4-nitrobenzenes by rat glutathione S-transferase 4-4

Autor: Nico P. E. Vermeulen, M.J. de Groot, H. Van Der Goot, E. M. Van Der Aar, G. J. Bijloo

Publikováno v: van der Aar, E M, de Groot, M J, Bijloo, G J, van der Goot, H & Vermeulen, N P E 1996, ' Structure-activity relationships for the glutathione conjugation of 2-substituted 1-chloro-4-nitrobenzenes by rat glutathione S-transferase 4-4. ', Chemical Research in Toxicology, vol. 9, pp. 527-534 . https://doi.org/10.1021/tx9501391
Chemical Research in Toxicology, 9, 527-534. American Chemical Society

In the present study structure--activity relationships (SAR's) are described for the experimentally determined kinetic parameters (Km, kappa cat, and kappa cat/Km) of the GST 4-4-catalyzed reaction between GSH and 10 2-substituted 1-chloro-4-nitroben

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3436a180acf32c0b98bc336e977758
https://hdl.handle.net/1871/25469

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Isoquinoline and quinazoline urea analogues as antagonists for the Human Adenosine A3 receptor

Autor: H. Van Der Goot, Wiro M. P. B. Menge, J.E. van Muijlwijk-Koezen, M.J. de Groot, F Frijtag von Drabbe Kunzel, Adriaan P. IJzerman, Henk Timmerman

Publikováno v: van Muijlwijk-Koezen, J E, Timmerman, H, van der Goot, H, Menge, W M P B, Frijtag von Drabbe Kunzel, F, de Groot, M & IJzerman, A P 2000, ' Isoquinoline and quinazoline urea analogues as antagonists for the Human Adenosine A3 receptor ', Journal of the American Chemical Society . https://doi.org/10.1021/jm000002u
Journal of the American Chemical Society. American Chemical Society

Isoquinoline and quinazoline urea derivatives were found to bind to human adenosine A(3) receptors. Series of N-phenyl-N'-quinazolin-4-ylurea derivatives and N-phenyl-N'-isoquinolin-1-ylurea derivatives were synthesized and tested in radioligand bind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d55384d03bd200ded4ff1af0ee1ff8c
https://research.vu.nl/ws/files/1685859/130066.pdf

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Modeling the active sites of cytochrome P450s and glutathione S-transferases, two of the most important biotransformation enzymes

Autor: Nico P. E. Vermeulen, M.J. de Groot

Publikováno v: de Groot, M J & Vermeulen, N P E 1997, ' Modeling the active sites of cytochrome P450s and glutathione S-transferases, two of the most important biotransformation enzymes. ', Drug Metabolism Reviews, vol. 29, pp. 747-799 . https://doi.org/10.3109/03602539709037596
Drug Metabolism Reviews, 29, 747-799. Informa Healthcare

(1997). Modeling the Active Sites of Cytochrome P450s and Glutathione S-Transferases, two of the Most Important Biotransformation Enzymes. Drug Metabolism Reviews: Vol. 29, No. 3, pp. 747-799.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9165e5ff25de39fd9d95625b5c1b915
https://pubmed.ncbi.nlm.nih.gov/9262946

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