Zobrazeno 1 - 10
of 62
pro vyhledávání: '"M.H.M. van Herwijnen"'
Autor:
M.C.T Verheijen, J. Krauskopf, F. Caiment, M. Nazaruk, Q.F. Wen, M.H.M. van Herwijnen, D.A. Hauser, M. Gajjar, C. Verfaillie, Y. Vermeiren, P.P. De Deyn, M.M.J. Wittens, A. Sieben, S. Engelborghs, W. Dejonckheere, K. Princen, G. Griffioen, E.L. Roggen, J.J. Briedé
Publikováno v:
Toxicology Letters, 356, 89-99. Elsevier Ireland Ltd
Toxicology letters
Toxicology Letters 356 (2022)
Toxicology Letters, 356, 89-99
Toxicology letters
Toxicology Letters 356 (2022)
Toxicology Letters, 356, 89-99
Alzheimer's disease (AD) is the most common cause of dementia, characterized by the progressive impairment of cognition and memory loss. Sporadic AD (sAD) represents approximately 95 % of the AD cases and is induced by a complex interplay between gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3882331ce49c22cc5d5838535349c6d
https://lirias.kuleuven.be/handle/20.500.12942/697974
https://lirias.kuleuven.be/handle/20.500.12942/697974
Autor:
Jens M. Kelm, S. Messner, T. M. de Kok, Jian Jiang, M.H.M. van Herwijnen, Danyel Jennen, J.C.S. Kleinjans
Publikováno v:
Toxicology Letters, 312, 34-44. Elsevier Ireland Ltd
Inflammation is one of the factors that may increase the sensitivity of hepatic cells to acetaminophen (APAP) induced toxicity. To investigate the mechanisms, we exposed 3-dimensional (3D) Human Liver Microtissues, a co-culture of primary human hepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b284f6f67c1475aa6ddc29b7c7a153
https://doi.org/10.1016/j.toxlet.2019.05.004
https://doi.org/10.1016/j.toxlet.2019.05.004
Akademický článek
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Publikováno v:
Toxicology Letters. 350:S127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82f47caaece3128d505fd867b3ed7ea9
https://doi.org/10.1016/s0378-4274(21)00545-2
https://doi.org/10.1016/s0378-4274(21)00545-2
Autor:
M.H.M. van Herwijnen, J. Zhao, Celien Vreuls, M.A.J. van den Broek, Maarten L. J. Coonen, Sander S. Rensen, Cornelius H. C. Dejong, S. W. M. Olde Damink, Marlon J. Jetten, Danyel Jennen
Publikováno v:
HPB. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5ebfbf3c3a35a02e6bb0f29e12c37d
Publikováno v:
Toxicology Letters. 295:S65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c99c71796ea05bd2da9b6dada6bff6
https://doi.org/10.1016/j.toxlet.2018.06.068
https://doi.org/10.1016/j.toxlet.2018.06.068
Autor:
M.H.M. van Herwijnen, J.H.M. van Delft, Rob Stierum, W.J. Maas, Jos C. S. Kleinjans, Heleen M. Wortelboer, Anne S. Kienhuis
Publikováno v:
Toxicology in Vitro, 21(5), 892-901. Elsevier Science
Toxicology in Vitro, 5, 21, 892-901
Toxicology in Vitro, 5, 21, 892-901
A rapid decline of cytochrome P450 (CYP450) enzyme activities remains a drawback of rat hepatocyte-based in vitro cultures. Consequently, judgment of the toxic potential of compounds that need bioactivation by CYP450s may not be adequate using this m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d031951081cfdb2cbfa01194fa5a43a
https://doi.org/10.1016/j.tiv.2007.01.010
https://doi.org/10.1016/j.tiv.2007.01.010
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
M. S. E. Van Der Veer, Rob H. Stierum, Geja J. Hageman, Jos C. S. Kleinjans, M.H.M. van Herwijnen
Publikováno v:
Nutrition and Cancer-An International Journal, 32(2), 113-120. Routledge/Taylor & Francis Group
Department of Health Risk Analysis and Toxicology, Universiteit Maastricht, The Netherlands.As a substrate for poly(ADP-ribose) polymerase (PARP; EC, 2.4.2.30), an enzyme that is activated by DNA strand breaks and is thought to facilitate efficient D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02560f32e5767c371e1ed117bf4c925
https://doi.org/10.1080/01635589809514728
https://doi.org/10.1080/01635589809514728
Autor:
John J.M. Engelen, Ivo H. Zwingmann, M.H.M. van Herwijnen, Tj. Smid, I.J. Welle, P.A.E.L. Schilderman, Jos C. S. Kleinjans
Publikováno v:
Environmental and Molecular Mutagenesis, 32(2), 121-129. Wiley
Department of Health Risk Analysis and Toxicology, Maastricht University, The Netherlands.j.kleinjans@GRAT.unimaas.nlThis study set out to analyze biomarkers for genotoxic events, e.g., oxidative DNA damage, chromosomal damage and hprt mutations, amo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f46807c2f668e33944a5b70f2a0ea4
https://doi.org/10.1002/(sici)1098-2280(1998)32:2<121::aid-em7>3.0.co
https://doi.org/10.1002/(sici)1098-2280(1998)32:2<121::aid-em7>3.0.co