LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice

Autor: P.J. Tacken, B. Teusink, M.C. Jong, D. Harats, L.M. Havekes, K. Willems van Dijk, M.H. Hofker

Publikováno v: Journal of Lipid Research, Vol 41, Iss 12, Pp 2055-2062 (2000)

The very low density lipoprotein receptor (VLDLR) has been proposed to play a role in the delivery of fatty acids to peripheral tissues. However, despite reduced adipose tissue mass in VLDLR-deficient (VLDLR-/-) mice, this has been difficult to subst

Externí odkaz: https://doaj.org/article/cfe667e1e5cb428eb7ded3dc8cf3943e

Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver

Autor: K.W. van Dijk, van Harry Goor, Miek C. Jong, van Marja Luyn, Arjen R. Mensenkamp, Louis M. Havekes, Vincent W. Bloks, Peter J. Voshol, M.H. Hofker, Folkert Kuipers, Rick Havinga

Publikováno v: Journal of Biological Chemistry, 50, 274, 35711-35718
The Journal of Biological Chemistry, 274(50), 35711-35718. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC

ApoE-deficient mice on low fat diet show hepatic triglyceride accumulation and a reduced very low density lipoprotein (VLDL) triglyceride production rate. To establish the role of apoE in the regulation of hepatic VLDL production, the human APOE3 gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179cf6ce75b58c10731c5f6dd170f28e
https://research.rug.nl/en/publications/6dd0f2df-46a3-427a-8d2a-195a506fd621

Contents Vol. 88, 2000

Autor: P.A. Voûte, D. Baudry, C.L. Keck-Waggoner, K. White, P.I. Patel, J.C. McHale, M. Busson-Leconiat, M. Pagano, C. Wiesmeijer, G.W. Conrad, M. Pettenati, P. Staeheli, E.R. Zabarovsky, C. Tiziana Storlazzi, Y. Xie, Z.E. Zehner, E. Gabrielson, C.A. Griffin, C. Geffrotin, E.A. Isakova, P. Spencer, J.E. Hewitt, A. Barbon, E. Sonnhammer, R.M. Schmid, B. Kazmierczak, P. Munclinger, F. Vitelli, N.A. Serdyukova, S.W. Scherer, B.G. Beatty, S. Meloche, M. Schmid, Y. Nakajima, M. Riemann, B. Brintnell, J. Laborda, N. Zijlstra, P.M. Brickell, L.A. James, J. Pellerin, T.K. Kwon, K. Yamakawa, P. van Tuinen, B.S. Klein, H.-J. Han, H. Winton, S.H. Elsea, D. Frynta, Y. Nakamura, M. Guttenbach, L. Carim, V.G. Malikov, M. van Geel, J.C.T. van Deutekom, U. Zechner, S. Barlati, P.A. Kroner, C.N. Vlangos, R. Podowski, N.C. Popescu, M.N. Meyer, I. Kärkkäinen, Ian Dunham, L. Leikepová, S. Beck, M. Escarceller, S. Bonné, F. Favara, S. Fineschi, F. Van Roy, J. Zima, E.S. Tasheva, T.P. Lushnikova, H.C. Duba, A.L. Hawkins, R. Berger, S. Sanders, J.M. Varley, Y. Furukawa, A.V. Polyakov, A. Protopopov, E.R. Werner, R.J.L.F. Lemmers, N. Andreu, A. van Staalduinen, J. Piálek, P.J. de Jong, E. Gubina, P.L. Perelman, L. Sumoy, M. Iizaka, A. Renieri, M. Loda, S. Ferraboli, C. Wahlestedt, M.H. Hofker, K. Vehse, H.M. Cann, C.F. Inglehearn, Lidia Larizza, P. Adamson, M.D. Torres, P. Benda, J. van Hengel, I. Meloni, E. Aikawa, H. Himmelbauer, M.A. Alvarez Soria, O.V. Sablina, E.E. Tarttelin, J. Justesen, R. Gizatullin, M.N. Ahmed, R. Karhu, Andries Westerveld, R.R. Frants, Mariano Rocchi, Cécile Jeanpierre, A. Marquardt, H. Hayes, S. Behrends, M. Erdel, P. Das, D.J Haile, J. Sádlová, R. Godbout, H. Markholst, N.V. Vorobieva, V.A. Trifonov, A.S. Graphodatsky, M. Ogawa, B.H.F. Weber, D.S. Chiaur, A. Duval, Marja Steenman, I. Nanda, C. Von Kap-Her, C. Cenciarelli, Marcel M.A.M. Mannens, K. Imai, W. Parks, T. Ueda, L. Hornum, H. Scholz, H. Akashi, D.L. Kruitbosch, W. Bradford, V. Kashuba, G. Inghirami, A.B. McKie, H. Hameister, K. Gopalbhai, Y. Hey, M.J. Ruiz-Hidalgo, S.S. Thorgeirsson, L.L. Hansen, D.B. Zimonjic, G.W. Padberg, A.J. Mungall, X. Estivill, J. Bullerdiek, D. Demetrick, G. Frelat, M.B. Qumsiyeh, G. Werner-Felmayer, I. Leverkoehne, S. Ganesh, S. Halford, K.-R. Kim, J. Greenwood, N. Kanda, C. Le Chalony, M.C. Dickson, H. Stöhr, J. Trowsdale, K. Amano, R. Hamelin, S. Sugano, S. Liptay, K. Sakamaki, A.-P.J. Huovila, A. Ziegler, A.D. Gruber, G. Zhao, S. Nagata, L. Zhu, V. Baladrón, P.M. Borodin, S. Murthy, D.M. Hunt, M. Meyer

Publikováno v: Cytogenetic and Genome Research. 88:337-339

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::659295b074d9fc4bfd4382ff1dade74e
https://doi.org/10.1159/000015526

No evidence for cholinergic problems in apolipoprotein E knockout and apolipoprotein E4 transgenic mice

Autor: L.M Havekens, F. Van Leuven, Francisca C. Bronfman, Ina Tesseur, M.H Hofker

Publikováno v: Neuroscience. 97(3)

The varepsilon4 allele of the apolipoprotein E gene constitutes the major genetic risk factor to develop Alzheimer's disease. If and how this protein contributes to the pathological cascade of Alzheimer's disease is not known. The varepsilon4 allele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57edb7616d3eee8b210b6be0af0c4b57
https://pubmed.ncbi.nlm.nih.gov/10828523

Het einde van hart- en vaatziekten nabij: Feit of fictie?

Autor: M.H. Hofker

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecab7a84e3bb3af62fcacca4dde2b4c2
https://doi.org/10.26481/spe.20001207mh