Zobrazeno 1 - 10
of 146
pro vyhledávání: '"M.H. Cullen"'
Publikováno v:
The Oncologist. 4:470-477
Palliative chemotherapy is defined as treatment in circumstances where the impact of intervention is insufficient to result in major survival advantage, but does affect improvement in terms of tumor-related symptoms, and where the palliation/toxicity
Publikováno v:
Clinical Oncology. 10:372-376
The effect of neoadjuvant chemotherapy in patients with apparently operable adenocarcinoma of the oesophagus has been investigated. Two courses of mitomycin, cisplatin and 5-fluorouracil (MCF) were given, followed by a radiological evaluation of resp
Autor:
Sophie D. Fosså, M.H. Cullen, Gordon J. S. Rustin, G. Read, Stan B. Kaye, S. P. Stenning, S. J. Harland, Nina Aass, P. A. Cook, Alan Horwich, R.T.D. Oliver, G. M. Duchesne, I. T. Roberts, Graham M. Mead
Publikováno v:
European Journal of Cancer. 33:829-835
In a retrospective study, data from 302 patients with metastatic testicular seminoma treated with chemotherapy between 1978 and 1990 in 10 European centres were analysed to evaluate the role, if any, of postchemotherapy treatment with irradiation. Th
Autor:
M.H. Cullen
Publikováno v:
Lung Cancer. 9:81-89
The three most active single agents against non-small cell lung cancer (NSCLC) are mitomycin, ifosfamide, and cisplatin, which have been associated with response rates of 20, 26 and 20%, respectively. A Phase II study was therefore commenced to evalu
Publikováno v:
Clinical Oncology. 10:170-172
The effect of brief neoadjuvant chemotherapy in patients with apparently operable adenocarcinoma of the oesophagus has been investigated. Two courses of cisplatin and 5-fluorouracil (CFu) were given, followed by evaluation of the response by barium s
Publikováno v:
Cancer Chemotherapy and Pharmacology. 37:496-498
We evaluated the effect of brief neoadjuvant chemotherapy in patients with apparently operable adenocarcinoma of the oesophagus. Two courses of mitomycin (6 mg/m2), ifosfamide (3 g/m2) and cisplatin (50 mg/m2; MIC) were given followed by evaluation o
Publikováno v:
Clinical Oncology. 3:46-48
We report the apparently spontaneous regression of metastatic disease in a young man who had previously undergone orchidectomy for a primary testicular teratoma. Serial serum tumour marker estimations revealed a sharp rise followed by a spontaneous d
Autor:
L. de Prijck, S.B. Kaye, I. Bodrogi, C.J. van Groeningen, E. Lallemand, L. Collette, R de Wit, G.M. Mead, M.H. Cullen, SP Stenning, P.H.M. de Mulder, Sophie D. Fosså
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 16(2)
PURPOSE To determine the effect of r-metHu granulocyte colony-stimulating factor (G-CSF) on the proportion of patients with metastatic poor-prognosis malignant germ cell tumors who receive full dose-intensity combination chemotherapy. PATIENTS AND ME
Autor:
Hannah Farrant, Christian H. Ottensmeier, Kate Fife, Michael J. Seckl, C. Wadsworth, Peter Schmid, M.H. Cullen, LE James, Gary Middleton, B. Crosse, Iftekhar Khan, D Muthukumar, Joyce Thompson, Susan Harden, Paul D. Taylor
Publikováno v:
Journal of Clinical Oncology. 31:7595-7595
7595 Background: Most SCLC patients initially respond to chemotherapy but then relapse and die so new therapies are urgently required. Pre-clinical data shows statins induce growth arrest and apoptosis in SCLC and several other tumour cell types and
Publikováno v:
Clinical oncology (Royal College of Radiologists (Great Britain)). 8(5)
Alpha-foetoprotein (AFP) is wideley used in the diagnosis, therapeutic monitoring and follow-up of patients with germ cell tumours. On occasion, the interpretation of a raised serum AFP measurement in a patient is confounded by the fact that AFP also