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Publikováno v:
Analytica Chimica Acta. 127:135-145
Previously published differential pulse methods for the determination of certain progestogens (laevonorgestrel and norethisterone) are not applicable to combined low-dosage oral contraceptives because interference from excipients in the tablets compl
Autor:
M.H. Briggs
Publikováno v:
Contraception. 12:149-153
Human blood plasma contains beta-globulin (molecular weight about 100000) which shows high binding affinity for both estradiol 17-beta and testosterone. It is called the sex hormone binding globulin (SHBG). There is a 4-8 fold increase during pregnan
Publikováno v:
Analytica Chimica Acta. 138:35-45
Mercury electrodes are oxidized in the presence of ethynyloestradiol, a synthetic steroid. The direct polarographic response obtained is based on the formation of an insoluble mercury compound. In analytical applications of this response, interferenc
Autor:
M.H. Briggs, T. Cheung
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 54(1)
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 22(11)
We tested 64 perfumes and aftershaves for mutagenicity in Salmonella typhimurium strains TA98 and TA100; most were tested both with and without metabolic activation. None of the test compounds gave a positive mutagenic response. The available amounts
Publikováno v:
Journal of chromatography. 315
Reversed-phase high-performance liquid chromatography with UV detection is studied for the determination of both progestogenic and oestrogenic components of oral contraceptive formulations. The applicability of the assay is demonstrated for a number
Autor:
M.H. Briggs
Publisher Summary This chapter discusses the endocrine effects of combined oral contraceptive (OC) preparations. It reviews reported changes in modern laboratory tests of endocrine status occurring in women using combined OC. The changes can vary wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e6f43801022fa9de9ef29e3d3c53d52
https://doi.org/10.1016/b978-0-08-027336-5.50023-6
https://doi.org/10.1016/b978-0-08-027336-5.50023-6
Autor:
M.H. Briggs
Publikováno v:
Biochimica et biophysica acta. 280(3)
Sterile homogenates of Schistosoma mansoni convert a variety of steroids to related metabolites. Homogenates of worms from mice treated with steroid inhibitors show altered steroid metabolism. Several of the inhibitors significantly reduced numbers o