Zobrazeno 1 - 10
of 35
pro vyhledávání: '"M.G. Saed"'
Autor:
Awoniyi O. Awonuga, Husam M. Abu-Soud, Mili Thakur, Jashoman Banerjee, Sana N. Khan, Jing Dai, Iyad Ali, M.G. Saed, Faten Shaeib
Publikováno v:
Reproductive Sciences. 23:498-507
We investigated the ability of reactive oxygen species (ROS), such as hydrogen peroxide (H(2)O(2)), hydroxyl radical ((·)OH), and hypochlorous acid (HOCl), to overcome the defensive capacity of cumulus cells and elucidate the mechanism through which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80bb41a1eedd2ad05840170ef0be9de8
https://doi.org/10.1177/1933719115607993
https://doi.org/10.1177/1933719115607993
Autor:
M.G. Saed, Husam M. Abu-Soud, S. Abuanzeh, Ayman Al-Hendy, Ghassan M. Saed, Nicole M. Fletcher, Michael P. Diamond
Publikováno v:
Reproductive Sciences. 21:1145-1152
Uterine fibroids are the most common benign tumor in women. The goal of this study was to investigate whether nicotinamide adenine dinucleotide phosphate oxidase (NOX), a major source of superoxide and subsequent oxidative stress, was differentially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d5ca391dbc56e809661f9f1dd0ceda
https://doi.org/10.1177/1933719114522552
https://doi.org/10.1177/1933719114522552
Autor:
M.G. Saed, Husam M. Abu-Soud, Nicole M. Fletcher, Michael P. Diamond, Awoniyi O. Awonuga, Ghassan M. Saed
Publikováno v:
Systems Biology in Reproductive Medicine. 60:14-20
Postoperative adhesions are a common medical complication of gynecologic and other pelvic surgeries resulting in persistent pelvic pain, obstruction of the intestines, and even infertility. The molecular mechanisms of postoperative adhesion developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5e8ef4f4afc67a31cb1f3890fbb92b
https://doi.org/10.3109/19396368.2013.847129
https://doi.org/10.3109/19396368.2013.847129
Autor:
M.G. Saed, Ghassan M. Saed, Ayman Al-Hendy, Ira Memaj, Mohammed S. Abusamaan, Michael P. Diamond, Nicole M. Fletcher
Publikováno v:
Fertility and sterility. 107(6)
Objective To determine the effects of attenuating oxidative stress with the use of dichloroacetate (DCA) on the expression of key redox enzymes myeloperoxidase (MPO) and inducible nitric oxide synthase (iNOS) as well as on apoptosis. Design Prospecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925c51bdfb8c54fa3a1ce972d0f9d801
https://pubmed.ncbi.nlm.nih.gov/28483502
https://pubmed.ncbi.nlm.nih.gov/28483502
Autor:
Osama Nusrat, Nicole M. Fletcher, Jimmy Belotte, Ghassan M. Saed, M.G. Saed, Ira Memaj, Michael P. Diamond
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 23(11)
Chemoresistance remains a major challenge in the treatment of ovarian cancer. As part of a survival mechanism, tumor cells have been shown to release proangiogenic factors, such as vascular endothelial growth factor (VEGF), through a mechanism that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319a315febe83ac65eeff65316ecf00d
https://pubmed.ncbi.nlm.nih.gov/27122375
https://pubmed.ncbi.nlm.nih.gov/27122375
Autor:
B.R. Neubauer, Michael P. Diamond, M.G. Saed, Mohammed S. Abusamaan, Ghassan M. Saed, Awoniyi O. Awonuga, Nicole M. Fletcher
Publikováno v:
Fertility and sterility. 104(4)
Objective To compare the effect of shifting anaerobic to aerobic metabolism on key regulators of oxidative stress, including extracellular superoxide dismutase (SOD3), inducible nitric oxide synthase (iNOS), and its product, nitric oxide (NO), as wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3fac212d9e34725f69a2bbff1100630
https://pubmed.ncbi.nlm.nih.gov/26297645
https://pubmed.ncbi.nlm.nih.gov/26297645
Publikováno v:
Gynecologic Oncology. 145:38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66d2111568c67a69a00ae405b29f797b
https://doi.org/10.1016/j.ygyno.2017.03.098
https://doi.org/10.1016/j.ygyno.2017.03.098
Autor:
Michael P. Diamond, Ghassan M. Saed, Nicole M. Fletcher, S. Abuanzeh, M.G. Saed, Husam M. Abu-Soud
We have previously reported that superoxide (O2 •–) contributes to the development of postoperative adhesions. In this study, we determined whether O2 •– generating nicotinamide adenine dinucleotide phosphate oxidase (NOX) is differentially e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eae9cf4b956d362701cb7eb2214d122
https://europepmc.org/articles/PMC5933105/
https://europepmc.org/articles/PMC5933105/
The role of oxidative stress in the development of cisplatin resistance in epithelial ovarian cancer
Autor:
Michael P. Diamond, Awoniyi O. Awonuga, Ghassan M. Saed, Nicole M. Fletcher, Mitchell Alexis, M.G. Saed, Husam M. Abu-Soud, Jimmy Belotte
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 21(4)
To investigate the role of oxidative stress in the development of cisplatin resistance in epithelial ovarian cancer (EOC).Two parent EOC cell lines (MDAH-2774 and SKOV-3) and their chemoresistant counterparts (cisplatin, 50 µmol/L) were used. Total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2f07cf969b2c0e09024c72aadbd382
https://pubmed.ncbi.nlm.nih.gov/24077440
https://pubmed.ncbi.nlm.nih.gov/24077440
Autor:
Michael P. Diamond, Nicole M. Fletcher, Ghassan M. Saed, Husam M. Abu-Soud, M.G. Saed, Ayman Al-Hendy
Publikováno v:
Journal of assisted reproduction and genetics. 30(7)
Fibroids are the most common smooth muscle overgrowth in women. This study determined the expression and the effect of hypoxia on two potent antioxidant enzymes, superoxide dismutase (SOD) and catalase (CAT) on human fibroid cells.Immortalized human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a229c8f648206096e0081d0e7f5e511
https://pubmed.ncbi.nlm.nih.gov/23812845
https://pubmed.ncbi.nlm.nih.gov/23812845