Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M.E. Haddon"'
Autor:
Samuel J. Machin, L. Winkelman, J. K. Smith, M.E. Haddon, Ian J. Mackie, Brian T. Colvin, Mary Ainsworth
Publikováno v:
Clinical & Laboratory Haematology. 8:85-92
Summary Three patients who have been given intermediate purity NHS heat-treated factor VIII concentrate have been followed prospectively for 7–10 months. None had previously received more than six donor units of blood products containing factor VII
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739ff99f81dbf0f6a3a89f45742aaabd
https://doi.org/10.1111/j.1365-2257.1986.tb00082.x
https://doi.org/10.1111/j.1365-2257.1986.tb00082.x
Autor:
Helena M. Daly, M.E. Haddon
Publikováno v:
Thrombosis and Haemostasis. 59:171-174
SummaryA three-day-old infant presented with umbilical haemorrhage. Factor XIII deficiency was diagnosed. When one month old she commenced prophylactic injections of pasteurised factor XIII concentrate of human plasma origin. During two and a half ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23bb090c3bcd7ce81e2136b3dafe0122
https://doi.org/10.1055/s-0038-1642748
https://doi.org/10.1055/s-0038-1642748
Autor:
J. K. Smith, J. D. Williams, R.S. Lane, L. Winkelman, M.E. Haddon, D. R. Evans, Owen Ne, H. Evans, Prince Pj
Publikováno v:
Vox Sanguinis. 57:97-103
A new method for the manufacture of a heated factor VIII concentrate of high specific activity (2-6 IU factor VIII:C/mg protein) has been developed. Addition of heparin to cryoprecipitate extract at acid pH precipitated fibrinogen and fibronectin. Fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171733f80dd7d9f189007bf88b152521
https://doi.org/10.1111/j.1423-0410.1989.tb01144.x
https://doi.org/10.1111/j.1423-0410.1989.tb01144.x
Publikováno v:
Thrombosis and Haemostasis. 55:402-405
SummaryA therapeutic concentrate of factor XIII containing both A and B sub-units has been prepared from 300 kg pools of human plasma. The process starts from a cold-ethanol fraction from cryoprecipitate supernatant and therefore does not interfere w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c857c169a5e207a331980724ac14693d
https://doi.org/10.1055/s-0038-1661573
https://doi.org/10.1055/s-0038-1661573
Autor:
L. Winkelman, N.E. Owen, D.R. Evans, H. Evans, M.E. Haddon, J.K. Smith, P.J. Prince, J.D. Williams, R.S. Lane
Publikováno v:
Vox Sanguinis. 57:97-103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c1d678b3699d7e1840171692f67f316
https://doi.org/10.1159/000461015
https://doi.org/10.1159/000461015
Autor:
Christopher V. Prowse, Thomas A. McQuillan, Joyce Ferguson, Janet D. Littlewood, J Dawes, J. K. Smith, M.E. Haddon, Peter R. Foster, P.A. Feldman
Publikováno v:
British Journal of Haematology. 65:463-468
Summary. This study examines the effects of heat treatment for 72 h at 80°C on the potential thrombogenicity of lyophilized human coagulation factor IX concentrates. Since heating generated minor amounts of thrombin, concentrate was prepared with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477470ed9ae0a2628eac593cb50fb453
https://doi.org/10.1111/j.1365-2141.1987.tb04151.x
https://doi.org/10.1111/j.1365-2141.1987.tb04151.x
Publikováno v:
Vox sanguinis. 48(6)
A method for large-scale production of a pasteurized antithrombin III (AT III) concentrate for therapeutic use has been adapted from published methods. It includes the following steps: (1) batchwise adsorption onto heparin-Sepharose from plasma deple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1768c72972a947f81c3ed4e6386fb090
https://pubmed.ncbi.nlm.nih.gov/4013136
https://pubmed.ncbi.nlm.nih.gov/4013136
Autor:
L. Winkelman, M.E. Haddon
Publikováno v:
Thrombosis research. 43(2)
The changes that take place when a therapeutic antithrombin III (AT III) concentrate is heated in the presence of citrate ion have been assessed. There is some loss of heparin cofactor antithrombin activity and of heparin binding ability. Protein agg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0747d2750ccd97d5beae299e91197e
https://pubmed.ncbi.nlm.nih.gov/3738862
https://pubmed.ncbi.nlm.nih.gov/3738862
Publikováno v:
British journal of haematology. 17(2)
Summary. The inhibitor-neutralizing ability of plasma and Factor-VIII concentrates from a group of 48 haemophilic patients and 30 normal persons has been studied. Factor-VIII inhibitors were neutralized by the material from four of the haemophilic pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4141a28f699bb9e77a9d988321d615
https://pubmed.ncbi.nlm.nih.gov/5306640
https://pubmed.ncbi.nlm.nih.gov/5306640
Publikováno v:
Thrombosis Research. 41:36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f1657fb5903009e402f1c75941575ba
https://doi.org/10.1016/0049-3848(86)91417-9
https://doi.org/10.1016/0049-3848(86)91417-9