Výsledky vyhledávání - "M.E. Callender"

Randomized controlled trial assessing the effect of simvastatin in primary biliary cirrhosis

Autor: David R. McCance, Mark E. O'Donnell, M.E. Callender, Jane McEneny, Ian S. Young, N. I. McDougall, William J. Cash, Stephen O'Neill

Publikováno v: Liver International. 33:1166-1174

Background This study evaluated the effect of statins in Primary biliary cirrhosis (PBC) on endothelial function, anti-oxidant status and vascular compliance. Methods Primary biliary cirrhosis patients with hypercholesterolaemia were randomized to re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53956af32f4d6630bdd08acf570d58b
https://doi.org/10.1111/liv.12191

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Primary biliary cirrhosis is associated with oxidative stress and endothelial dysfunction but not increased cardiovascular risk

Autor: Jane McEneny, M.E. Callender, N. I. McDougall, William J. Cash, David R. McCance, Ian S. Young, I.S. Cadden

Publikováno v: Hepatology Research. 40:1098-1106

Aim: Primary biliary cirrhosis (PBC) is a chronic cholestatic disease which is associated with hypercholesterolaemia. Further, cholestatic diseases are associated with deficiencies of anti-oxidant vitamins. Despite these associations PBC is not assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f7847879bc7a2bd25b1630343dab99d
https://doi.org/10.1111/j.1872-034x.2010.00717.x

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Safety and efficacy of combined use of sildenafil, bosentan, and iloprost before and after liver transplantation in severe portopulmonary hypertension

Autor: Elizabeth Sizer, Carol M. Wilson, Mark J Austin, Mohammed Rela, Michael A. Heneghan, Julia Wendon, John O'Grady, N. I. McDougall, A. S. Knisely, M.E. Callender

Publikováno v: Liver Transplantation. 14:287-291

Portopulmonary hypertension (PPHTN) represents a constrictive pulmonary vasculopathy in patients with portal hypertension. Liver transplantation (LT) may be curative and is usually restricted to patients with mild-to-moderate disease severity charact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67e3cd7541e64a0022203d179583fb87
https://doi.org/10.1002/lt.21310

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Endothelial function, antioxidant status and vascular compliance in newly diagnosed HFE C282Y homozygotes

Autor: Mark E. O'Donnell, Jane McEneny, David R. McCance, William J. Cash, N. I. McDougall, M.E. Callender, Stephen O'Neill, Ian S. Young

Publikováno v: Advances in medical sciences. 59(1)

Purpose This pilot study was aimed to establish techniques for assessing and observing trends in endothelial function, antioxidant status and vascular compliance in newly diagnosed HFE haemochromatosis during the first year of venesection. Patients/m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a480a3dff836485ac81ca5cbe9ebce
https://pubmed.ncbi.nlm.nih.gov/24797970

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Antioxidant status and lipid peroxidation in hereditary haemochromatosis

Autor: Dorothy McMaster, Jonathan J. Torney, M.E. Callender, Ian S. Young, Tom G. Trouton, Elisabeth R. Trimble

Publikováno v: Free Radical Biology and Medicine. 16:393-397

Hereditary haemochromatosis is characterized by iron overload that may lead to tissue damage. Free iron is a potent promoter of hydroxyl radical formation that can cause increased lipid peroxidation and depletion of chain-breaking antioxidants. We ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05adef53a565eee0256f56711bf50ff9
https://doi.org/10.1016/0891-5849(94)90041-8

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d-Penicillamine therapy in patients with HBsAg-negative chronic active hepatitis and major prednisolone-induced adverse effects

Autor: B.M. McClements, M.E. Callender

Publikováno v: Journal of Hepatology. 11:322-325

Six patients with histologically proven HBsAg-negative chronic active hepatitis (CAH), who were initially treated successfully with prednisolone with or without azathioprine, developed unacceptable adverse effects due to prednisolone. In all six pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e527e3b2cf5a15307758e095ac3564
https://doi.org/10.1016/0168-8278(90)90215-d

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High incidence of the Cys 282 Tyr mutation in the HFE gene in the Irish population--implications for haemochromatosis

Autor: Martin D. Curran, Derek Middleton, M.E. Callender, C.J. O'Brien, N. McDougall, S. Murphy

Publikováno v: Tissue antigens. 52(5)

A simple PCR-SSOP approach based on a single PCR product has been developed to screen the HFE gene for the haemochromatosis-associated mutations Cys 282 Tyr and His 63 Asp. Using this approach the prevalence of these mutations in a cohort (30) of hae

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e3971b6a184d1749988afb9192a764
https://pubmed.ncbi.nlm.nih.gov/9864039

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