Výsledky vyhledávání - "M.C. Carbone"

Alterations in the protein kinase C signaling activated by a parthenogenetic agent in oocytes from reproductively old mice

Autor: Carla Tatone, M.C. Carbone

Publikováno v: Molecular Reproduction and Development. 76:122-131

To investigate the effect of female age on oocyte developmental competence, we focused on protein kinase C (PKC), a major component of the signalling pathway involved in oocyte activation, and put forward the hypothesis that, as it occurs in many org

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0832818480aad2e7a791e723e7895db1
https://doi.org/10.1002/mrd.20923

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Age-Associated Changes in Mouse Oocytes During Postovulatory In Vitro Culture: Possible Role for Meiotic Kinases and Survival Factor BCL21

Autor: Rita Gallo, M.C. Carbone, Mario Di Cola, Edoardo Alesse, Simona Delle Monache, Fernanda Amicarelli, Carla Tatone

Publikováno v: Biology of Reproduction. 74:395-402

To elucidate molecular mechanisms underlying oocyte senescence, we investigated whether oocytes from female mice of advanced reproductive age exhibit a precocious postovulatory aging that, in turn, may be responsible for the precocious activation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea69560c33549f2c139694e28f17c057
https://doi.org/10.1095/biolreprod.105.046169

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The Cosmic Silence experiment: on the putative adaptive role of environmental ionizing radiation

Autor: Giustina Simone, M.C. Carbone, Eugenio Sorrentino, Orazio Sapora, M. Balata, Mauro Belli, M. A. Tabocchini, L. Ioannucci, S. Nisi, M. Pinto, Fernanda Amicarelli, L. Satta, F. Antonelli, L. Conti Devirgiliis

Publikováno v: Radiation and environmental biophysics. 48(2)

Previously we reported that yeast and Chinese hamster V79 cells cultured under reduced levels of background environmental ionizing radiation show enhanced susceptibility to damage caused by acute doses of genotoxic agents. Reduction of environmental

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8db143b7b57d36c5fcb2e8d7e114709
https://pubmed.ncbi.nlm.nih.gov/19169701

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Cellular and molecular aspects of ovarian follicle ageing

Autor: Donatella Caserta, M.C. Carbone, Paola Piomboni, Paolo Giovanni Artini, Riccardo Focarelli, Carla Tatone, Roberto Marci, Fernanda Amicarelli, Patrizia Monteleone

It is well established that age-related decline of the biological capacity of a woman to reproduce is primarily related to the poor developmental potential of her gametes. This renders female ageing the most significant determinant of success in IVF.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd5b20d2994e091f8393dd107b62b50
http://hdl.handle.net/11365/23828

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Chronic exposure to 50 Hz magnetic fields causes a significant weakening of antioxidant defence systems in aged rat brain

Autor: M.C. Carbone, Maria A. Mariggiò, Silvia Di Loreto, Vincenzo Zimmitti, Rosa Mancinelli, Carmine Di Ilio, Fernanda Amicarelli, Alessandro Mirabilio, Stefano Falone

Publikováno v: International journal of biochemistry & cell biology 40 (2008): 2762–2770. doi:10.1016/j.biocel.2008.05.022
info:cnr-pdr/source/autori:S. Falone a; A. Mirabilio a; M. C. Carbone b; V. Zimmitti b; S. Di Loreto c; M.A. Mariggiò d; R. Mancinelli d; C. Di Ilio a; F. Amicarelli b./titolo:Chronic exposure to 50 Hz magnetic fields causes a significant weakening of antioxidant defence systems in aged rat brain./doi:10.1016%2Fj.biocel.2008.05.022/rivista:International journal of biochemistry & cell biology/anno:2008/pagina_da:2762/pagina_a:2770/intervallo_pagine:2762–2770/volume:40

Several studies suggest that extremely low-frequency magnetic fields (ELF-MFs) may enhance the free radical endogenous production. It is also well known that one of the unavoidable consequences of ageing is an overall oxidative stress-based decline i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d11e395fab27d58730655809b87e70
http://www.cnr.it/prodotto/i/5347

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Possible involvement of integrin-mediated signalling in oocyte activation: evidence that a cyclic RGD-containing peptide can stimulate protein kinase C and cortical granule exocytosis in mouse oocytes

Autor: M.C. Carbone, Carla Tatone

Publikováno v: Reproductive Biology and Endocrinology
Reproductive Biology and Endocrinology, Vol 4, Iss 1, p 48 (2006)

Background Mammalian sperm-oocyte interaction at fertilization involves several combined interactions between integrins on the oocyte and integrin ligands (disintegrins) on the sperm. Recent research has indicated the ability of peptides containing t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8bb7f2a4f5ac51ef76d28c580c0255
https://doi.org/10.1186/1477-7827-4-48

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Age-dependent changes in the expression of superoxide dismutases and catalase are associated with ultrastructural modifications in human granulosa cells

Autor: M.C. Carbone, Roberto Marci, Donatella Caserta, Pierpaolo Aimola, Annalisa Giardinelli, Anna Maria Ragnelli, Assunta Pandolfi, Carla Tatone, Stefano Falone, Fernanda Amicarelli

Limited knowledge exists about changes in follicle quality associated with age. The aim of this work was to investigate whether ageing may cause oxidative stress-mediated alterations in human granulosa cells (GCs) from periovulatory follicles. GCs em

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6faeaf5bce0b2c92913e7e653e3a891
http://hdl.handle.net/11392/1402644

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Antioxidant enzymatic defences in human follicular fluid: characterization and age-dependent changes

Autor: Carla Tatone, Donatella Caserta, S. Delle Monache, Fernanda Amicarelli, R. Colonna, Roberto Marci, M.C. Carbone

Publikováno v: Molecular human reproduction. 9(11)

The aim of this work was to study the antioxidant enzymatic defences in human follicular fluid and investigate their possible changes during reproductive ageing. To this end, we tested the specific activities and protein expression of enzymes involve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a10b128289289cefc42a1d928e0583
https://pubmed.ncbi.nlm.nih.gov/14561807

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