Alterations in the protein kinase C signaling activated by a parthenogenetic agent in oocytes from reproductively old mice

Autor: Carla Tatone, M.C. Carbone

Publikováno v: Molecular Reproduction and Development. 76:122-131

To investigate the effect of female age on oocyte developmental competence, we focused on protein kinase C (PKC), a major component of the signalling pathway involved in oocyte activation, and put forward the hypothesis that, as it occurs in many org

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0832818480aad2e7a791e723e7895db1
https://doi.org/10.1002/mrd.20923

Dual-Action Therapeutics: DNA Alkylation and Antimicrobial Peptides for Cancer Therapy.

Autor: Andrés, Celia María Curieses¹ (AUTHOR) cmcuriesesa@saludcastillayleon.es, Pérez de la Lastra, José Manuel² (AUTHOR) jm.perezdelalastra@csic.es, Munguira, Elena Bustamante¹ (AUTHOR) ebustamante@saludcastillayleon.es, Andrés Juan, Celia³ (AUTHOR) celia.andres.juan@uva.es, Pérez-Lebeña, Eduardo⁴ (AUTHOR) info@glize.eu

Publikováno v: Cancers. Sep2024, Vol. 16 Issue 18, p3123. 44p.

Age-Associated Changes in Mouse Oocytes During Postovulatory In Vitro Culture: Possible Role for Meiotic Kinases and Survival Factor BCL21

Autor: Rita Gallo, M.C. Carbone, Mario Di Cola, Edoardo Alesse, Simona Delle Monache, Fernanda Amicarelli, Carla Tatone

Publikováno v: Biology of Reproduction. 74:395-402

To elucidate molecular mechanisms underlying oocyte senescence, we investigated whether oocytes from female mice of advanced reproductive age exhibit a precocious postovulatory aging that, in turn, may be responsible for the precocious activation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea69560c33549f2c139694e28f17c057
https://doi.org/10.1095/biolreprod.105.046169

The Cosmic Silence experiment: on the putative adaptive role of environmental ionizing radiation

Autor: Giustina Simone, M.C. Carbone, Eugenio Sorrentino, Orazio Sapora, M. Balata, Mauro Belli, M. A. Tabocchini, L. Ioannucci, S. Nisi, M. Pinto, Fernanda Amicarelli, L. Satta, F. Antonelli, L. Conti Devirgiliis

Publikováno v: Radiation and environmental biophysics. 48(2)

Previously we reported that yeast and Chinese hamster V79 cells cultured under reduced levels of background environmental ionizing radiation show enhanced susceptibility to damage caused by acute doses of genotoxic agents. Reduction of environmental

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8db143b7b57d36c5fcb2e8d7e114709
https://pubmed.ncbi.nlm.nih.gov/19169701

Chronic exposure to 50 Hz magnetic fields causes a significant weakening of antioxidant defence systems in aged rat brain

Autor: M.C. Carbone, Maria A. Mariggiò, Silvia Di Loreto, Vincenzo Zimmitti, Rosa Mancinelli, Carmine Di Ilio, Fernanda Amicarelli, Alessandro Mirabilio, Stefano Falone

Publikováno v: International journal of biochemistry & cell biology 40 (2008): 2762–2770. doi:10.1016/j.biocel.2008.05.022
info:cnr-pdr/source/autori:S. Falone a; A. Mirabilio a; M. C. Carbone b; V. Zimmitti b; S. Di Loreto c; M.A. Mariggiò’ d; R. Mancinelli d; C. Di Ilio a; F. Amicarelli b./titolo:Chronic exposure to 50 Hz magnetic fields causes a significant weakening of antioxidant defence systems in aged rat brain./doi:10.1016%2Fj.biocel.2008.05.022/rivista:International journal of biochemistry & cell biology/anno:2008/pagina_da:2762/pagina_a:2770/intervallo_pagine:2762–2770/volume:40

Several studies suggest that extremely low-frequency magnetic fields (ELF-MFs) may enhance the free radical endogenous production. It is also well known that one of the unavoidable consequences of ageing is an overall oxidative stress-based decline i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d11e395fab27d58730655809b87e70
http://www.cnr.it/prodotto/i/5347