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Acellular Nerve Graft Enriched With Mesenchymal Stem Cells in the Transfer of the Phrenic Nerve to the Musculocutaneous Nerve in a C5-C6 Brachial Plexus Avulsion in a Rat Model

Autor: Nerea Comellas Melero, M.C. Arufe, Sara Alicia González Porto, Alba González Rodríguez

Publikováno v: RUC. Repositorio da Universidade da Coruña
instname

Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG [Abstract] Introduction: Phrenic nerve transfer has been shown to achieve good nerve regeneration in brachial plexus avulsion. Acellular nerve allografts (ANAs) showed infer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2caa73b45e9274436ec6080c71942263
https://hdl.handle.net/2183/28722

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Therapeutic Potential for Regulation of the Nuclear Factor Kappa-B Transcription Factor p65 to Prevent Cellular Senescence and Activation of Pro-Inflammatory in Mesenchymal Stem Cells

Autor: Rocío Mato-Basalo, Juan Fafián-Labora, Fons A. J. van de Loo, Miriam Morente-López, M.C. Arufe, Onno J. Arntz

Publikováno v: International Journal of Molecular Sciences
RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
International Journal of Molecular Sciences, Vol 22, Iss 3367, p 3367 (2021)
International Journal of Molecular Sciences, 22
Volume 22
Issue 7
RUC. Repositorio da Universidade da Coruña
instname
International Journal of Molecular Sciences, 22, 7

[Abstract] Mesenchymal stem cells have an important potential in the treatment of age-related diseases. In the last years, small extracellular vesicles derived from these stem cells have been proposed as cell-free therapies. Cellular senescence and p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a48482ad4f551ae631e8185ef96034
https://pubmed.ncbi.nlm.nih.gov/33805981

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Mesenchymal Stem Cell-Derived Extracellular Vesicle Isolation and Their Protein Cargo Characterization

Autor: Mónica Carrera, Miriam Morente-López, Jesús Mateos, Francisco J. de Toro, Juan Fafián-Labora, Concha Gil, M.C. Arufe

Publikováno v: Shotgun Proteomics ISBN: 9781071611777

In the present protocol, extracellular vesicles (EVs) released from a primary culture of human umbilical cord mesenchymal stem cells (MSCs) were isolated by ultracentrifugation processes, characterized by transmission electron microscopy (TEM) and me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::afd31e9b7cbb777268d9df66bee2d712
https://doi.org/10.1007/978-1-0716-1178-4_1

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Mesenchymal Stromal Cells for Articular Cartilage Repair: Preclinical Studies

Autor: C Rodellar, C Costa, M.C. Arufe, Maribel Marquina, P. Fernández-Pernas, L Barrachina

Publikováno v: RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
Dipòsit Digital de la UB
Universidad de Barcelona
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
RUC. Repositorio da Universidade da Coruña
Universitat Oberta de Catalunya (UOC)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
European Cells & Materials, Pp 88-114 (2020)

[Abstract] Rheumatic diseases such as osteoarthritis (OA) are a major social and economic burden because of the population aging and the lack of curative solutions. An effective cell therapy may be the best treatment option for OA and other cartilage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f8027ddbc2aa65e66bc716972414fe
http://hdl.handle.net/2183/26467

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Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their role in ageing

Autor: Miriam Morente-López, María José Sánchez-Dopico, Javier de Toro, Juan Fafián-Labora, Fons A. J. van de Loo, Onno J. Arntz, M.C. Arufe

Publikováno v: Stem Cell Research & Therapy, 11
RUC. Repositorio da Universidade da Coruña
instname
Stem Cell Research & Therapy, 11, 1
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)

Introduction This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced ageing and pluripotency markers in cell cultures where they are added. Methods MSC-derived extracellular vesicles from old and young rat bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914df92372cdec6807cb6fc31a5aa6eb
http://hdl.handle.net/2066/216661

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Akademický článek

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Effect of Aging on Behaviour of Mesenchymal Stem Cells

Autor: M.C. Arufe, Juan Fafián-Labora, Miriam Morente-López

Publikováno v: RUC. Repositorio da Universidade da Coruña
instname
World Journal of Stem Cells

[Abstract] Organs whose source is the mesoderm lineage contain a subpopulation of stem cells that are able to differentiate among mesodermal derivatives (chondrocytes, osteocytes, adipocytes). This subpopulation of adult stem cells, called “mesench

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13824f0adcd0cec56024361255d7ee43
https://hdl.handle.net/2183/24068

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3, 3′, 5-triiodo-L-thyronine Increases In Vitro Chondrogenesis of Mesenchymal Stem Cells From Human Umbilical Cord Stroma Through SRC2

Autor: Fco. Blanco García, M.C. Arufe, Javier De Toro Santos, Alexandre De la Fuente, Iván Lesende-Rodriguez, I. Fuentes, Jesús Mateos, P. Fernández-Pernas, Juan Fafián-Labora

Publikováno v: Journal of Cellular Biochemistry. 117:2097-2108

Our group focuses on the study of mesenchymal stem cells (MSCs) from human umbilical cord stroma or Warthons jelly and their directed differentiation toward chondrocyte-like cells capable of regenerating damaged cartilage when transplanted into an in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07ab16cbbc746ddcfe53568a4c22cf9c
https://doi.org/10.1002/jcb.25515

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