Zobrazeno 1 - 10
of 96
pro vyhledávání: '"M.A. Villanúa"'
Autor:
Estibaliz Castillero, Ana Isabel Martín, M.A. Villanúa, Miriam Granado, Asunción López-Calderón, María López-Menduiña
Publikováno v:
Molecular and Cellular Endocrinology. 309:8-16
The aim of this work was to analyse the evolution of the ubiquitin-proteasome, the myogenic regulatory factors, and the IGF-I system during the development of experimental arthritis. Arthritis was induced by adjuvant injection and rats were killed 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cedab84765ad7e7d008b0d845a9d49c9
https://doi.org/10.1016/j.mce.2009.05.017
https://doi.org/10.1016/j.mce.2009.05.017
Autor:
Miriam Granado, Ana Isabel Martín, Estibaliz Castillero, Asunción López-Calderón, M.A. Villanúa
Publikováno v:
European Journal of Pharmacology. 608:97-103
Chronic arthritis leads to a decrease in body weight that is associated with a decrease in skeletal muscle and white adipose tissue mass. We have observed that overactivation of cyclooxygenase-2 (COX-2) is responsible for muscle wasting in arthritic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f1ff8e2a91c59194d5cf092170a502
https://doi.org/10.1016/j.ejphar.2009.02.030
https://doi.org/10.1016/j.ejphar.2009.02.030
Autor:
M.A. Villanúa, María López-Menduiña, Ana Isabel Martín, Miriam Granado, Asunción López-Calderón, Estibaliz Castillero
Publikováno v:
Journal of Endocrinology. 198:385-394
The aim of this work was to analyse the role of cyclooxygenase-2 (Ptgs2) in endotoxin-induced decrease in Igf1 and Igf binding protein-3 (Igfbp3). For this purpose, male Wistar rats were injected with lipolysaccharide (LPS) and/or the Ptgs2 inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41e18a31f0627610e7c922676b08f5a3
https://doi.org/10.1677/joe-08-0205
https://doi.org/10.1677/joe-08-0205
Autor:
Ana Isabel Martín, Miriam Granado, Estibaliz Castillero, Asunción López-Calderón, María López-Menduiña, M.A. Villanúa
Publikováno v:
Journal of Endocrinology. 197:111-119
Adjuvant-induced arthritis is a model of rheumatoid arthritis that induces cachexia. In other cachectic situations, there is an increase in lipolysis resulting in a loss of adipose tissue mass. The aim of this work was to analyse the effect of chroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43f93f9ac0ca3b5b994960f06a75daa
https://doi.org/10.1677/joe-07-0491
https://doi.org/10.1677/joe-07-0491
Publikováno v:
Journal of Endocrinology. 191:319-326
Chronic inflammation is associated with a decrease in body weight and cachexia, which is characterized by anorexia and skeletal muscle wasting. The expression of atrogens muscle RING finger-1 (MuRF-1) and muscle atrophy F-box (MAFbx) are increased in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323fbf655e520437a011efb8ad5e1257
https://doi.org/10.1677/joe.1.06931
https://doi.org/10.1677/joe.1.06931
Publikováno v:
Journal of Endocrinology. 188:503-511
Gram-negative bacterial infection or treatment of animals with bacterial lipopolysaccharide (LPS) induces a catabolic state with proteolysis, liver injury and an inhibition of the insulin-like growth factor-I (IGF-I) system. The purpose of this work
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1044ffd5a2ff8894e7ca93b20f4355
https://doi.org/10.1677/joe.1.06585
https://doi.org/10.1677/joe.1.06585
Autor:
Ana Isabel Martín, Inmaculada Ibáñez de Cáceres, M.A. Villanúa, Asunción López-Calderón, Teresa Priego
Publikováno v:
Journal of Endocrinology. 172:449-456
The aim of this work was to elucidate the possible role of glucocorticoids in the bacterial lipopolysaccharide (LPS)-induced decrease in hepatic IGF-I synthesis. For this purpose, we studied the effect of LPS on IGF-I in two rat strains, Wistar and L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76a5119531e0e5c5406497f3b3c6d2d
https://doi.org/10.1677/joe.0.1720449
https://doi.org/10.1677/joe.0.1720449
Autor:
Asunción López-Calderón, María López-Menduiña, Estibaliz Castillero, Ana Isabel Martín, M.A. Villanúa
Publikováno v:
Growth hormoneIGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 22(1)
Adjuvant-induced arthritis is an experimental model of rheumatoid arthritis that inhibits the GH-IGF-I axis and decreases body weight gain and muscle mass. Although chronic GH or IGF-I treatment increases body weight gain in arthritic rats, muscle re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83d48bb2d939c60bec4c21cd92d4bf4
https://pubmed.ncbi.nlm.nih.gov/22244673
https://pubmed.ncbi.nlm.nih.gov/22244673
Autor:
M.A. Villanúa, Ana Isabel Martín, Inmaculada Ibáñez de Cáceres, Asunción López-Calderón, Teresa Priego
Publikováno v:
ResearcherID
Experimental arthritis induced by Freund-adjuvant administration is a model of chronic inflammation and rheumatoid arthritis associated with a decrease in pituitary growth hormone (GH) and hepatic insulin-like growth factor I (IGF-I) gene expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d84cba28a104dc76bbd72c030b46da
https://pubmed.ncbi.nlm.nih.gov/14636180
https://pubmed.ncbi.nlm.nih.gov/14636180
Autor:
M.A. Villanúa, J. M. P. Holly, Ana Isabel Martín, Inmaculada Ibáñez de Cáceres, Asunción López-Calderón, Teresa Priego
Publikováno v:
The Journal of endocrinology. 173(2)
Adjuvant-induced arthritis is a chronic inflammatory illness that induces a catabolic state, with a decrease in pituitary GH and hepatic IGF-I synthesis. We have previously observed an increase in serum IGF-binding protein-3 (IGFBP-3) in arthritic ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba925c3877e683382ebc568b06e404aa
https://pubmed.ncbi.nlm.nih.gov/12010643
https://pubmed.ncbi.nlm.nih.gov/12010643