Výsledky vyhledávání - "M.A. Timóteo"

Amplification of neuromuscular transmission by methylprednisolone involves activation of presynaptic facilitatory adenosine A2A receptors and redistribution of synaptic vesicles

Autor: M.A. Timóteo, Celia Regina Ambiel, Isabel Silva, Paulo Correia-de-Sá, José Bernardo Noronha-Matos, Walter L.G. Cavalcante, Ana C. Costa, Laura Oliveira, A.P. Corrado, Wilson Alves-Do-Prado, C. A. Dal Belo

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

The mechanisms underlying improvement of neuromuscular transmission deficits by glucocorticoids are still a matter of debate despite these compounds have been used for decades in the treatment of autoimmune myasthenic syndromes. Besides their immunos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee584ec18dabd8715c4922c9c12ea9cc
https://doi.org/10.1016/j.neuropharm.2014.09.004

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Neuromuscular paralysis by the basic phospholipase A2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit acetylcholine release and produce muscle blockage

Autor: Marcos R.M. Fontes, M.A. Timóteo, Walter L.G. Cavalcante, Márcia Gallacci, Paulo Correia-de-Sá, José Bernardo Noronha-Matos

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2018-12-11T17:14:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-11-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889e70239938a30826c427310f45ce76

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Bothropstoxin-I reduces evoked acetylcholine release from rat motor nerve terminals: Radiochemical and real-time video-microscopy studies

Autor: Cicília de Carvalho, Andreimar M. Soares, Paulo Correia-de-Sá, M.A. Timóteo, Walter L.G. Cavalcante, Márcia Gallacci, José Bernardo Noronha-Matos, Patrícia Isabel Marques, Fátima Ferreirinha

Publikováno v: Toxicon. 61:16-25

Understanding the biological activity profile of the snake venom components is fundamental for improving the treatment of snakebite envenomings and may also contribute for the development of new potential therapeutic agents. In this work, we tested t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ea173b72cf15dfeb1abe2f3cb0ef9e
https://doi.org/10.1016/j.toxicon.2012.10.014

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Tetanic failure due to decreased endogenous adenosine A2A tonus operating neuronal Cav1 (L-type) influx in Myasthenia gravis

Autor: M.T. Magalhães-Cardoso, José Bernardo Noronha-Matos, Laura Oliveira, Diogo Trigo, Paulo Correia-de-Sá, M.A. Timóteo, T. Morais

Publikováno v: Journal of Neurochemistry. 117:797-811

J. Neurochem. (2011) 117, 797–811. Abstract In healthy motor endplates, tetanic depression is overcome by tonic adenosine A2A-receptor-mediated facilitation of transmitter release. The A2A receptor operates a coordinated shift from fast-desensitizi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e79001b385d9f36603c204d27c934c2
https://doi.org/10.1111/j.1471-4159.2011.07216.x

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Relative contribution of ecto-ATPase and ecto-ATPDase pathways to the biphasic effect of ATP on acetylcholine release from myenteric motoneurons

Autor: Carlos Nascimento, Paulo Correia-de-Sá, M.A. Timóteo, Margarida Duarte-Araújo, M.T. Magalhães-Cardoso

Publikováno v: British Journal of Pharmacology. 156:519-533

The relative contribution of distinct ecto-nucleotidases to the modulation of purinergic signalling may depend on differential tissue distribution and substrate preference.Extracellular ATP catabolism (assessed by high-performance liquid chromatograp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea588dbb670caffa90632e5605400ad
https://doi.org/10.1111/j.1476-5381.2008.00058.x

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Tuning adenosine A1 and A2A receptors activation mediates l-citrulline-induced inhibition of [3H]-acetylcholine release depending on nerve stimulation pattern

Autor: Paulo Correia-de-Sá, A. Barroso, M.T. Magalhães-Cardoso, Wilson Alves-Do-Prado, M.A. Timóteo, Laura Oliveira, C. Silva, E. Campesatto-Mella

Publikováno v: Neurochemistry International. 52:834-845

The influence of nerve stimulation pattern on transmitter release inhibition by l -citrulline, the co-product of NO biosynthesis by nitric oxide synthase (NOS), was studied in the rat phrenic nerve-hemidiaphragm. We also investigated the putative int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670908955bba316c57b784fe1a1b12d3
https://doi.org/10.1016/j.neuint.2007.09.016

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L -Citrulline inhibits [3 H]acetylcholine release from rat motor nerve terminals by increasing adenosine outflow and activation of A1 receptors

Autor: Paulo Correia-de-Sá, M.A. Timóteo, Wilson Alves-Do-Prado, M.T. Magalhães-Cardoso, A. Barroso, Laura Oliveira, C. Silva, E. Campesatto-Mella

Publikováno v: British Journal of Pharmacology. 151:541-550

Background and purpose: Nitric oxide (NO) production and depression of neuromuscular transmission are closely related, but little is known about the role of L-citrulline, a co-product of NO biosynthesis, on neurotransmitter release. Experimental appr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b956802640fac2cb270f278735b3eb40
https://doi.org/10.1038/sj.bjp.0707242

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Negative crosstalk between M1 and M2 muscarinic autoreceptors involves endogenous adenosine activating A1 receptors at the rat motor endplate

Autor: M.A. Timóteo, Paulo Correia-de-Sá, Laura Oliveira

Publikováno v: Neuroscience letters. 459(3)

At the rat motor nerve terminals, activation of muscarinic M(1) receptors negatively modulates the activity of inhibitory muscarinic M(2) receptors. The present work was designed to investigate if the negative crosstalk between muscarinic M(1) and M(

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12482ee6df5853cbb672fe8f94a2ea08
https://pubmed.ncbi.nlm.nih.gov/19427366

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Synergism between A(2A)-adenosine receptor activation and vasoactive intestinal peptide to facilitate [3H]-acetylcholine release from the rat motor nerve terminals

Autor: Joaquim A. Ribeiro, M.A. Timóteo, Paulo Correia-de-Sá

Publikováno v: Neuroscience letters. 309(2)

The effect of vasoactive intestinal peptide (VIP) on evoked [ 3 H]-acetylcholine ([ 3 H]-ACh) release from motor nerve terminals, and its interaction with presynaptic facilitatory A 2A -adenosine receptors was investigated in the rat phrenic nerve-he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6d9a4daa7ba67180f225224ac28196
https://pubmed.ncbi.nlm.nih.gov/11502355

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