Zobrazeno 1 - 10
of 69
pro vyhledávání: '"M.A. Spirtes"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 5:121-124
Previous reports have indicated that alpha-MSH release inhibiting hormone (MIF-1) increased the behavior occurring as a result of the dihydroxyphenylalanine (DOPA) potentiation test [3,7]. This study was undertaken to see whether dopamine (DA) or nor
Publikováno v:
Neuropeptides. 1:391-400
MIF-1, at concentrations of 10−5 and 10−6M, induced stimulations of 53 and 57% respectively in a particulate, crude, brain mitochondrial fraction when guanosine-3′:5′-cyclic monophosphate (cyclic GMP, c-GMP) formation was measured by a radioi
Autor:
M.A. Spirtes, A.R. Freeman
Publikováno v:
Biochemical Pharmacology. 12:47-53
Different techniques were employed to study the effects of chlorpromazine on the permeability of human erythrocytes to various compounds. Preliminary experiments indicated that the drug reduced the rate of hemolysis in the presence of isotonic urea o
Autor:
Edward A. Brunner, M.A. Spirtes
Publikováno v:
Archives of Biochemistry and Biophysics. 106:176-181
The rates of anaerobic lactate and total acid production from glucose by liver slices of normal and thyroxine-injected rats have been determined and compared. The results indicate that observed differences in slice glycolytic response were due to cha
Autor:
P S Guth, M.A. Spirtes
Publikováno v:
Biochemical Pharmacology. 12:37-46
The swelling of rat liver mitochondria suspended in isotonic sucrose at pH 7.4 was measured spectrophotometrically and by water and sucrose entry. Chlorpromazine at concentrations of 5 × 10 −6 to 10 −4 M inhibited such swelling to the same degre
Autor:
M.A. Spirtes, A.R. Freeman
Publikováno v:
Clinica Chimica Acta. 8:641-644
Publikováno v:
Biochemical Pharmacology. 14:295-303
Sucrose entry, but not the entry of water, into rat liver mitochondria suspended in 0·15 M sucrose-0·02 M Tris buffer, pH 7·4, could be prevented by 3 × 10 −4 M cyanide. Water entry under such conditions consists of two phases. The first is a r
Autor:
M.A. Spirtes
Publikováno v:
Biochemical and Biophysical Research Communications. 4:71-75
Publikováno v:
Neuropharmacology. 19:687-689
Preliminary experiments with rough mitochondrial or synaptosomal rat brain preparations indicate that a statistically significant increase of from 50–70% in c-GMP production was obtained in the presence of melanocyte stimulating hormone release inh
Autor:
A.R. Freeman, M.A. Spirtes
Publikováno v:
Biochemical Pharmacology. 11:161-163