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Circulating progenitor cells in rheumatoid arthritis: association with inflammation and oxidative stress

Autor: Carlo Saitta, R. Lo Gullo, Antonino Saitta, Antonio David, A. Lo Gullo, M.A. Sardo, Enrico Maria Mormina, Egidio Imbalzano, Giuseppe Mandraffino, Saverio Loddo, R. Mandraffino, F. Mamone, Angela Alibrandi, Angela D'Ascola

Publikováno v: Scandinavian Journal of Rheumatology. 43:184-193

To evaluate the association between inflammation, oxidative stress, and circulating progenitor cell (CPC) number and redox equilibrium, vascular lesions and accelerated atherosclerosis in rheumatoid arthritis (RA).Circulating CD34+ cells were isolate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66342816bf3820ed2eeb085f97edbbd6
https://doi.org/10.3109/03009742.2013.836564

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Circulating progenitor cells are increased in newly diagnosed untreated hypertensive patients with arterial stiffening but normal carotid intima-media thickness

Autor: Antonino Saitta, Enrico Maria Mormina, Stefania Riggio, Giuseppe Mandraffino, Saverio Loddo, Angela Alibrandi, Carlo Saitta, Maurizio Cinquegrani, M.A. Sardo, Egidio Imbalzano

Publikováno v: Hypertension Research. 34:876-883

Circulating progenitor cells (CPCs), including endothelial progenitor cells (EPCs), have a key role in endothelium repair. Cellular NADPH oxidase (Nox) enzymes, including Nox-containing gp91phox, represent a source of reactive oxygen species (ROS); R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881cefbe3fe3448c61938d69e364b3f0
https://doi.org/10.1038/hr.2011.56

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Assessment of liver stiffness in subjects affected by familial combined hyperlipidaemia with hepatic steatosis

Autor: M.A. Sardo, Pier Francesco Tripodi, Stefania Riggio, Giuseppe Mandraffino, Giovanni Squadrito, Antonino Saitta, Angela Alibrandi, F. Mamone, Sergio Maimone, Carlo Saitta, Lauretta Manti

Publikováno v: European Journal of Clinical Investigation. 40:722-728

Eur J Clin Invest 2010; 40 (8): 722–728 Abstract Background Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of diseases ranging from simple steatosis to nonalcoholic steatohepatitis (NASH) and is associated with familial combined hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee5047fbf1003d3b80f2a7a8eb563885
https://doi.org/10.1111/j.1365-2362.2010.02323.x

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Endothelial Progenitor Cells for Diagnosis and Prognosis in Cardiovascular Disease

Autor: M.A. Sardo, Michele Scuruchi, Antonino Saitta, F. Mamone, Giorgio Basile, Egidio Imbalzano, Giuseppe Mandraffino, C.O. Aragona, Alberto Lo Gullo, V. Cairo, Angela D'Ascola

Publikováno v: Stem Cells International
Stem Cells International, Vol 2016 (2016)

Objective. To identify, evaluate, and synthesize evidence on the predictive power of circulating endothelial progenitor cells (EPCs) in cardiovascular disease, through a systematic review of quantitative studies.Data Sources. MEDLINE was searched usi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54addb59b32c13d4e1ab92a4172299dc
https://pubmed.ncbi.nlm.nih.gov/26839569

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Vitamin D Status in Rheumatoid Arthritis: Inflammation, Arterial Stiffness and Circulating Progenitor Cell Number

Autor: Antonino Saitta, Giuseppe Mandraffino, Antonio Giovanni Versace, Renato Lo Gullo, Egidio Imbalzano, Enricomaria Mormina, Angela D'Ascola, Saverio Loddo, Alberto Lo Gullo, C.O. Aragona, Antonella Cinquegrani, Gianluca Bagnato, Francesco Rotondo, M.A. Sardo, Carlo Saitta

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0134602 (2015)

Background and aims Suboptimal vitamin D status was recently acknowledged as an independent predictor of cardiovascular diseases and all-cause mortality in several clinical settings, and its serum levels are commonly reduced in Rheumatoid Arthritis (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb883e573425867137cab2febe221569
https://pubmed.ncbi.nlm.nih.gov/26241902

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Tissue factor expression and activity are not increased in peripheral monocytes isolated from uncomplicated hypertensive patients

Autor: M.A. Sardo, Antonio Bonaiuto, Alessandra Bitto, Carlo Saitta, Maria Castaldo, Antonino Saitta, Salvatore Campo, Giuseppe Trimarchi, Simona Cristadoro

Publikováno v: Journal of Hypertension. 24:731-736

Background Systemic hypertension is one of the main risk factors for atherothrombosis. Tissue factor (TF) is found in the adventitia of blood vessels and in the lipid core of atherosclerotic plaques, and is specifically expressed on monocyte or macro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbf82378cb1c8d96e0886793b8cbf3a
https://doi.org/10.1097/01.hjh.0000217856.82122.b1

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Antioxidant effect of atorvastatin is independent of PON1 gene T(–107)C, Q192R and L55M polymorphisms in hypercholesterolaemic patients

Autor: Alessandra Bitto, Antonino Saitta, Michele Bonaiuto, Maurizio Cinquegrani, Antonio Bonaiuto, Carlo Saitta, M.A. Sardo, Maria Castaldo, Salvatore Campo, Giuseppe Trimarchi

Publikováno v: Current Medical Research and Opinion. 21:777-784

Serum paraoxonase (PON1), a high density lipoprotein (HDL)-bound antioxidant enzyme, plays a role in atherosclerosis. An increase in PON1 activity has been reported following statin treatment.In the present study the following factors were evaluated:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f9c4667bec8792fbc144833981b42c
https://doi.org/10.1185/030079905x45170

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The paraoxonase promoter polymorphism (−107)T>C is not associated with carotid intima-media thickness in Sicilian hypercholesterolemic patients

Autor: Antonino Saitta, Salvatore Campo, Giuseppe Trimarchi, M.A. Sardo, Antonio Bonaiuto, Maria Castaldo, Luisa Fontana, Carlo Saitta, Alessandra Bitto, Michele Bonaiuto

Publikováno v: Clinical Biochemistry. 37:388-394

Background and Objectives: Increased plasma low-density lipoprotein-cholesterol (LDL-C) levels in hypercholesterolemic subjects are associated with enhanced LDL oxidation that represents an additional risk for atherosclerotic disease. Human serum par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b40abbe900ac1dda30fb9f4aaf75ab
https://doi.org/10.1016/j.clinbiochem.2003.12.012

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