Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M.A. Pellett"'
Publikováno v:
International Journal of Pharmaceutics. 263:173-181
Supersaturation is a very useful method of enhancing the permeation of drugs across membranes such as skin, because unlike other methods, it does not interfere with the ultrastructure of the stratum corneum. Many drugs are able to form inclusion comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5aba92dca503e9ff4e168425f2f9a2
https://doi.org/10.1016/s0378-5173(03)00366-1
https://doi.org/10.1016/s0378-5173(03)00366-1
Publikováno v:
International Journal of Pharmaceutics. 193:27-35
For diabetic patients, blood glucose monitoring is an important part in the management of their disease, however the acquisition of blood requires the use of invasive and often painful methods, and the development of a technique that removes these pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ca179a25ab5cd218370990dc1e67af
https://doi.org/10.1016/s0378-5173(99)00314-2
https://doi.org/10.1016/s0378-5173(99)00314-2
Publikováno v:
International Journal of Pharmaceutics. 154:217-227
In this study, the morphological structure of the inner and outer regions of human stratum corneum (SC) were investigated using Attenuated Total Reflectance Fourier Transform Infra-Red (ATR-FTIR) spectroscopy. Furthermore, diffusional pathlengths in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44fa31f8e476ca59ca7a8d4ec27e94b9
https://doi.org/10.1016/s0378-5173(97)00143-9
https://doi.org/10.1016/s0378-5173(97)00143-9
Publikováno v:
Journal of Controlled Release. 46:205-214
Under ideal circumstances, maximum flux is achieved from saturated solutions and, therefore, the diffusion of compounds from supersaturated solutions would provide enhanced penetration. However, due to the inherent lack of stability of supersaturated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a7374180951b4eac92b98a92b18542f
https://doi.org/10.1016/s0168-3659(96)01595-7
https://doi.org/10.1016/s0168-3659(96)01595-7
Publikováno v:
International Journal of Pharmaceutics. 111:1-6
Subsaturated, saturated and supersaturated solutions of piroxicam were prepared in a propylene glycol/water cosolvent system. The diffusion of these solutions across a model membrane of Silastic® was investigated. It was shown that in a single cosol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c78d0d79e7c0a9e529d37fbc7575b013
https://doi.org/10.1016/0378-5173(94)90395-6
https://doi.org/10.1016/0378-5173(94)90395-6
Autor:
S.L Raghavan, D. M. Green, Mohammed Husein Nazemi, Jonathan Hadgraft, Marc B. Brown, Faith M. Williams, Anthony E. Beezer, C. S. Roper, Barrie Charles Finnin, C. A. Jarvis, Sheree E. Cross, Annette L. Bunge, Lionel Trottet, Eugene E. Ley, Fumio Kamiyama, Akira Yamamoto, S. E. Burgess, Hemali B. Gunt, Gerald B. Kasting, A C Watkinson, M. Dias, Sally Innis Brain, B. D. Traversa, D. Schenk, Graham Stephen Mcnaughton, A. Farinha, R. L. Gwyther, Robert P. Chilcott, M.A. Pellett, Simon Wilkinson, J. du Plessis, Namrata D. Barai, Simon John Gallagher, A. Simpson, S. T. Lim, Michael S. Roberts, Wayne J. Romonchuk, Andrew Morris, Charles Martin Heard, Christopher H. Dalton, L. Simonsen, Ying-Shu Quan
In vitro measurements of skin absorption are an increasingly important aspect of regulatory studies, product support claims, and formulation screening. However, such measurements are significantly affected by skin variability. The purpose of this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1cee9420dae4909f082be863114053
https://cronfa.swan.ac.uk/Record/cronfa48361
https://cronfa.swan.ac.uk/Record/cronfa48361
Publikováno v:
Dermatological and Transdermal Formulations ISBN: 9780429164323
I. INTRODUCTION Because of the barrier properties of the stratum corneum and, also, depending on the physicochemical properties of the drug, transport from simple vehicles will often be insufficient to achieve therapeutic drug concentrations at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bbbeff0d828c137876196929c3c9185
https://doi.org/10.1201/9780824743239-9
https://doi.org/10.1201/9780824743239-9
Publikováno v:
European Journal of Pharmaceutical Sciences. 4:S174
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9f9263d6a36865d5aac665da98dfd25
https://doi.org/10.1016/s0928-0987(97)86524-4
https://doi.org/10.1016/s0928-0987(97)86524-4
Publikováno v:
European Journal of Pharmaceutical Sciences. 4:S145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1043efbf9061a533fb2fe3e7d24489ec
https://doi.org/10.1016/s0928-0987(97)86435-4
https://doi.org/10.1016/s0928-0987(97)86435-4
Autor:
Chilcott, R.P., Barai, N., Beezer, A.E., Brain, S.I., Brown, M.B., Bunge, A.L., Burgess, S.E., Cross, S., Dalton, C.H., Dias, M., Farinha, A., B.C., Finnin, S.J., Gallagher, D.M., Green, H., Gunt, R.L., Gwyther, C.M., Heard, C.A., Jarvis, F., Kamiyama, G.B., Kasting, E.E., Ley, S.T., Lim, G.S., Mcnaughton, A., Morris, M.H., Nazemi, M.A., Pellett, J., DU Plessis, Y.S., Quan, S.L., Raghavan, M., Roberts, W., Romonchuk, C.S., Roper, D., Schenk, L., Simonsen, A., Simpson, B.D., Traversa, L., Trottet, A., Watkinson, S.C., Wilkinson, F.M., Williams, A., Yamamoto, J., Hadgraft
Publikováno v:
Journal of Pharmaceutical Sciences; March 2005, Vol. 94 Issue: 3 p632-638, 7p