Zobrazeno 1 - 10
of 113
pro vyhledávání: '"M.-J. Galmier"'
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 30:85-90
The purpose of this work was to investigate the interest of the TEER measurement, a quite simple measure, as an evaluation of toxicity, in function of time and level of drug in the experimental medium, for different anticalcic agents. The extend of t
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Publikováno v:
Biomedical Chromatography. 9:32-35
A capillary gas chromatographic method with mass-selective detection was developed for the determination of oxeladin in human plasma. Plasma samples (1 mL) were alkalinized and extracted using 5mL of hexane: isoamyl alcohol (99:1). The method was dem
Publikováno v:
Biomedical Chromatography. 14:202-204
A high-performance liquid chromatographic method for the simultaneous determination of phenylephrine and tropicamide in human aqueous humor was developed. After centrifugation, an aliquot of the supernatant was injected onto the column and the eluent
Autor:
J.A. Berger, M. J. Galmier, A Enreille, N Busch, C. Lartigue-Mattei, J.F. Pognat, J.L. Chabard
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 16:161-172
CERM 3517 (mociprazine), a new anti-emetic compound, was administered orally to six beagle dogs at 10 mg/kg b.i.d. for four days. Unconjugated urinary metabolites were identified by GC-MS analysis against synthesized reference compounds, after solven
Publikováno v:
Xenobiotica. 21:1371-1384
1. Beagle dogs were treated orally (10 mg/kg) with para-chloro-, para-fluoro- and para-methyl-phenylpiperazine derivatives, and urine was collected for 72 h after treatment. 2. Metabolites were extracted, converted into trimethylsilyl (TMS) derivativ
Autor:
M. J. Galmier, O. Andriollo, J.A. Berger, J. Petit, J.L. Chabard, H. Bargnoux, J.F. Pognat, C. Lartigue-Mattei
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 533:215-223
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Autor:
E Noirault, El Mostapha Azim, Claire Lartigue, M J Galmier, J Legailliard, J Helfenbein, Jean-Claude Madelmont
Publikováno v:
Journal of medicinal chemistry. 45(26)
The use of isotopic substitution to delay the oxidative metabolism of the anesthetic propofol 1 was studied. The aromatic hydrogens of propofol 1 were replaced by deuterium to produce the mono- and trideuterated derivatives 4 and 5. In vitro metaboli
Publikováno v:
Biomedical chromatography : BMC. 14(3)
A high-performance liquid chromatographic method for the simultaneous determination of phenylephrine and tropicamide in human aqueous humor was developed. After centrifugation, an aliquot of the supernatant was injected onto the column and the eluent