Zobrazeno 1 - 10
of 58
pro vyhledávání: '"M.-H. Siess"'
Publikováno v:
Food and Chemical Toxicology
Food and Chemical Toxicology, Elsevier, 2001, 39, pp.981-987
Food and Chemical Toxicology, Elsevier, 2001, 39, pp.981-987
Fruits and vegetables or their natural constituents which increase detoxication enzymes and/or reduce activating enzymes are considered as good candidates to prevent chemically-induced carcinogenesis. In this study, rats were fed a diet supplemented
Publikováno v:
Xenobiotica 12 (33), 1185-1199. (2003)
Xenobiotica
Xenobiotica, Taylor & Francis, 2003, 33 (12), pp.1185-1199. ⟨10.1080/00498250310001636840⟩
Xenobiotica
Xenobiotica, Taylor & Francis, 2003, 33 (12), pp.1185-1199. ⟨10.1080/00498250310001636840⟩
International audience; 1. The metabolism of diallyl disulphide was investigated in vitro with rat and human liver cell subfractions and ex vivo with an isolated perfused rat liver. 2. Diallyl disulphide was oxidized to diallylthiosulphinate by rat l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10de708a6eb2de356ca37ea821dbcf29
http://prodinra.inra.fr/record/16149
http://prodinra.inra.fr/record/16149
Autor:
M Suschetet, Hervé Goudonnet, Jean-Marie Heydel, M.-H Siess, P Debersac, Marie-Josèphe Amiot, Yves Artur
Publikováno v:
Food and Chemical Toxicology
Food and Chemical Toxicology, Elsevier, 2001, 39 (9), pp.907-918
Food and Chemical Toxicology, Elsevier, 2001, 39 (9), pp.907-918
The ability of rosemary to modulate cytochrome P450 (CYP) and detoxication enzymes in rat liver was evaluated by comparing the effects of dried leaves and leaf extracts with different chemical compositions: essential oil (EO) containing monoterpenes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aafb9c43740251e27e9320b447cb3e2
https://hal.inrae.fr/hal-02682157
https://hal.inrae.fr/hal-02682157
Autor:
C, Teyssier, M H, Siess
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 28(6)
The metabolism of dipropyl disulfide (DPDS), an Allium sulfur compound, was investigated in rat liver cell subfractions and in an isolated perfused rat liver. DPDS is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. The contribution of c
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(7)
The metabolism of diallyl disulfide (DADS), a garlic sulfur compound, was investigated in human liver microsomes. Diallyl thiosulfinate (allicin) was the only metabolite observed and its formation followed Michaelis-Menten kinetics with a Km = 0.61 +
Publikováno v:
Journal of toxicology and environmental health. 49(5)
Effects of continuous feeding flavonoids (flavone, flavanone, and tangeretin) on drug-metabolizing enzymes in rat liver were investigated to ascertain how long feeding is required to reach maximal induction and to determine whether maximal induction
Publikováno v:
Xenobiotica
Xenobiotica, Taylor & Francis, 1996, 26 (1), pp.49-63
Xenobiotica, Taylor & Francis, 1996, 26 (1), pp.49-63
1. The catalytic activities of several phase I and II xenobiotic-metabolizing enzymes and the immunochemical detection of P4501A and 2B have been investigated in liver microsomes and cytosol of male rats fed for 15 days with diets containing canthaxa
Publikováno v:
Xenobiotica
Xenobiotica, Taylor & Francis, 1994, 24 (2), pp.169-182
Xenobiotica, Taylor & Francis, 1994, 24 (2), pp.169-182
1. The effects of feeding allyl sulphides to rat (2000 ppm of the diet for 15 days) were investigated on various microsomal hepatic drug-metabolizing enzymes by their immunochemical detection and catalytic activity. 2. Allyl sulphides provoked a temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e36368e18dfb085105ceefb2282f07
https://hal.inrae.fr/hal-02713024
https://hal.inrae.fr/hal-02713024
Autor:
F. Waechter, H. Thomas, M. H. Siess, S. Gregoire, J. C. Lhuguenot, M. C. Cornu, M. Villermain
Publikováno v:
Peroxisomes ISBN: 9783642878091
Cytochromes P-450 are a superfamily of enzymes catalyzing the oxidation of numerous endogenous compounds (fatty acids, steroids, eicosanoids) and exogenous chemicals (drugs, pesticides, environmental pollutants). Based on DNA sequence homology, this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e00b00ceebaf24fc058e7a73489adb5
https://doi.org/10.1007/978-3-642-87807-7_9
https://doi.org/10.1007/978-3-642-87807-7_9
Autor:
M. H. Siess, C. Divies
Publikováno v:
European Journal of Applied Microbiology and Biotechnology. 12:10-15
The behaviour of Saccharomyces cerevisiae cells entrapped in a polyacrylamide gel was studied during their continuous function in an ethanol-producing reactor. Polymerization destroys 40% to 80% of the cells, depending on their physiological state. A