Zobrazeno 1 - 10
of 23
pro vyhledávání: '"M.-C. Shanafelt"'
Publikováno v:
Journal of Infectious Diseases. 170:978-985
Human inflammatory arthritic diseases developing in response to infections with known pathogens provide unique models for studying the molecular and cellular mechanisms underlying human chronic inflammatory diseases. For example, Lyme disease serves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36832bfa4f2a8335cd7cadbf8aafe0cb
https://doi.org/10.1093/infdis/170.4.978
https://doi.org/10.1093/infdis/170.4.978
Autor:
R Lahesmaa, M C Shanafelt, A Allsup, C Soderberg, J Anzola, V Freitas, C Turck, L Steinman, G Peltz
Publikováno v:
The Journal of Immunology. 150:4125-4135
Forty-three CD3+4+8- TCR alpha beta+ Borrelia burgdorferi-reactive T cell clones isolated from the peripheral blood of a single patient with clinically active chronic Lyme arthritis were characterized. The spirochetal Ag recognized by 16 of these T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c25acf95518d00b86269087655cf156
https://doi.org/10.4049/jimmunol.150.9.4125
https://doi.org/10.4049/jimmunol.150.9.4125
Publikováno v:
The Journal of Immunology. 148:218-224
We have characterized immunogenic epitopes of the 31-kDa outer surface protein A (OspA) protein of Borrelia burgdorferi, which is a major surface Ag of the spirochete causing Lyme disease. Full length and truncated forms of rOspA proteins were expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::899e6fcff88d605380add96e259fc469
https://doi.org/10.4049/jimmunol.148.1.218
https://doi.org/10.4049/jimmunol.148.1.218
Publikováno v:
The Journal of Immunology. 146:3985-3992
The reactivity of cloned T cells and serum antibodies, obtained from patients with chronic Lyme arthritis, with expressed recombinant B. burgdorferi 60-kDa heat shock protein homologue (HSP60) was analyzed. The expressed recombinant Borrelia burgdorf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ed97ee90afe22afdb0b18656b1384ff
https://doi.org/10.4049/jimmunol.146.11.3985
https://doi.org/10.4049/jimmunol.146.11.3985
Autor:
Erwin W. Gelfand, G Cieslewicz, R. Gundel, M.-C. Shanafelt, J. C. Pratt, Catherine Duez, Anthony Joetham, Adrian Tomkinson
Publikováno v:
ResearcherID
The closely related Th2 cytokines, IL-4 and IL-13, share many biological functions that are considered important in the development of allergic airway inflammation and airway hyperresponsiveness (AHR). The overlap of their functions results from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1348f3a91a62bd456dd31fa9017ddb4
https://pubmed.ncbi.nlm.nih.gov/11313423
https://pubmed.ncbi.nlm.nih.gov/11313423
Autor:
Riitta Lahesmaa, C Soderberg, Hans Yssel, Gary Peltz, Daniel C. Adelman, Lawrence Steinman, M C Shanafelt
Publikováno v:
The Journal of allergy and clinical immunology. 98(2)
We have examined the level of surface expression and functional properties of leukocyte function associated antigen-1, very late antigen-4, and CD45 isoforms on a panel of human CD4+ T-cell clones representative of TH0, TH1, and TH2 cells. There were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45b2900a9a3c5fc3f05988db5b6f588
https://pubmed.ncbi.nlm.nih.gov/8757221
https://pubmed.ncbi.nlm.nih.gov/8757221
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(4)
Analysis of experimental animal models and human clinical samples has indicated that the selective activation of CD4+ T cell subsets with distinct profiles of cytokine production plays an important role in the pathogenesis of human inflammatory and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::312829b9ee24cb282f106c5fc85829cf
https://pubmed.ncbi.nlm.nih.gov/7836752
https://pubmed.ncbi.nlm.nih.gov/7836752
Publikováno v:
The Journal of Experimental Medicine
18 cloned T cell lines reactive with Borrelia burgdorferi proteins, all CD3+4+8-TCR-alpha/beta+ and restricted by HLA class II proteins, were isolated from four patients with chronic Lyme arthritis. Analysis of these T cell clones indicated that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaff3863ef43f9ceaa0ce75f8c199a50
https://pubmed.ncbi.nlm.nih.gov/1831490
https://pubmed.ncbi.nlm.nih.gov/1831490
Publikováno v:
Journla of Immunotherapy. 22:468
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6049305188d9eb1c718e404f1934c69a
https://doi.org/10.1097/00002371-199909000-00064
https://doi.org/10.1097/00002371-199909000-00064
Autor:
Foundation, Finnish Cultural, Foundation, Rheumatism, M.-C. Shanafelt was supported by a Syntex Post-Doctoral fellowship. R. Lahesmaa was supported by gra, the Myasthenia Gravis Foundation. DNAX Resea, Shanafelt, M.C., Yssel, H., Soderberg, C., Steinman, L., Adelman, D.C., Peltz, G., Lahesmaa, R.
Publikováno v:
The Journal of Allergy and Clinical Immunology; August 1996, Vol. 98 Issue: 2 p433-440, 8p