Zobrazeno 1 - 10 of 101 pro vyhledávání: '"M.-C. Guillin"'
1
A chronic hypercoagulable state in patients with β-thalassaemia major is already present in childhood
Autor: E. De Raucourt, Amiram Eldor, Y. C. Godefray, M. C. Guillin, Shmuel Gillis, Eliezer A. Rachmilewitz, Ada Goldfarb, A. Abramov, Ronen Durst, Jacques Maclouf, Esti Hyam
Publikováno v: British Journal of Haematology. 107:739-746
A higher than normal incidence of thromboembolic events has been observed in adult patients with beta-thalassaemia major (TM) and certain haemostatic anomalies found in these patients suggest the existence of a chronic hypercoagulable state. Thalassa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90b5dc3adfe1d528201f2ef86597f82f
https://doi.org/10.1046/j.1365-2141.1999.01758.x
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2
Cause of portal or hepatic venous thrombosis in adults: the role of multiple concurrent factors
Autor: M H, Denninger, Y, Chaït, N, Casadevall, S, Hillaire, M C, Guillin, A, Bezeaud, S, Erlinger, J, Briere, D, Valla
Publikováno v: Hepatology (Baltimore, Md.). 31(3)
According to a recent hypothesis, venous thrombosis results from the concurrence of several factors. This hypothesis was assessed in patients with portal or hepatic venous thrombosis by simultaneously investigating most of the currently identified pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::65176ed0cbe77e602fc52a8db0624e29
https://pubmed.ncbi.nlm.nih.gov/10706547
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3
A chronic hypercoagulable state in patients with beta-thalassaemia major is already present in childhood
Autor: A, Eldor, R, Durst, E, Hy-Am, A, Goldfarb, S, Gillis, E A, Rachmilewitz, A, Abramov, J, MacLouf, Y C, Godefray, E, De Raucourt, M C, Guillin
Publikováno v: British journal of haematology. 107(4)
A higher than normal incidence of thromboembolic events has been observed in adult patients with beta-thalassaemia major (TM) and certain haemostatic anomalies found in these patients suggest the existence of a chronic hypercoagulable state. Thalassa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::414d3c96599fd10c4e4099d82e7a6539
https://pubmed.ncbi.nlm.nih.gov/10606878
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4
Increased procoagulant activity of red blood cells from patients with homozygous sickle cell disease and beta-thalassemia
Autor: D, Helley, A, Eldor, R, Girot, R, Ducrocq, M C, Guillin, A, Bezeaud
Publikováno v: Thrombosis and haemostasis. 76(3)
It has recently been proved that, in vitro, red blood cells (RBCs) from patients with homozygous beta-thalassemia behave as procoagulant cells. The procoagulant activity of beta-thalassemia RBCs might be the result of an increased exposure of procoag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d51c1bcf1796ed4dc1ce84ff82ef577d
https://pubmed.ncbi.nlm.nih.gov/8883264
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5
Role of the thrombin insertion loop 144-155. Study of thrombin mutations W148G, K154E and a thrombin-based synthetic peptide
Autor: M C, Bouton, J L, Plantier, M, Dembak, M C, Guillin, M J, Rabiet, M, Jandrot-Perrus
Publikováno v: European journal of biochemistry. 229(2)
Thrombin is a multifunctional serine protease that plays a critical role in hemostasis. Crystallographic studies revealed that the insertion loop, residues 144-155 (human thrombin B chain numbering) located on the surface of thrombin, might be involv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::600ff4b13fb34a468cef387fe627b147
https://pubmed.ncbi.nlm.nih.gov/7744076
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7
Mechanism of the abnormal vitamin K-dependent gamma-carboxylation process in human hepatocellular carcinomas
Autor: M G, Huisse, M, Leclercq, J, Belghiti, J F, Flejou, J W, Suttie, A, Bezeaud, D W, Stafford, M C, Guillin
Publikováno v: Cancer. 74(5)
An important marker for hepatocellular carcinoma is the presence of des-gamma-carboxy (abnormal) prothrombin. However, the molecular basis for the reduced carboxylation of prothrombin is unknown.Two groups of patients were defined according to the ab
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::456a6dbe314eb17d8147204a09655deb
https://pubmed.ncbi.nlm.nih.gov/7520347
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8
Paris I dysfibrinogenemia: a point mutation in intron 8 results in insertion of a 15 amino acid sequence in the fibrinogen gamma-chain
Autor: J B, Rosenberg, P J, Newman, M W, Mosesson, M C, Guillin, D L, Amrani
Publikováno v: Thrombosis and haemostasis. 69(3)
Paris I dysfibrinogenemia results in the production of a fibrinogen molecule containing a functionally abnormal gamma-chain. We determined the basis of the molecular defect using polymerase chain reaction (PCR) to amplify the gamma-chain region of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8a0d4b3739fdaf102852c3ae36f49e40
https://pubmed.ncbi.nlm.nih.gov/8470043
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9
An acquired antithrombin autoantibody directed toward the catalytic center of the enzyme
Autor: M C Guillin, B Boneu, G Archipoff, D Dupouy, J M Dugoujon, G Serre, J M Freyssinet, A Bezeaud, P Sie
Antibody inhibitors against human thrombin are rare and have remained poorly characterized. We report the case of a 40-yr-old patient who developed a potent thrombin inhibitor revealed by mild bleeding symptoms and marked prolongation of most laborat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac1b14a09143ca33aaf35816872c537
https://europepmc.org/articles/PMC296031/
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