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Are healthcare workers at higher risk of HIV infection than the general population in Burkina Faso?

Autor: Nicolas Nagot, M.-C. Defer, Fati Kirakoya-Samadoulougou, S. Yaro, P. Fao, Annie Robert, N. Meda

Publikováno v: Epidemiol Infect

SUMMARYIn order to assess the HIV prevalence in healthcare workers (HCWs) in Burkina Faso, we conducted a national survey in 97 health facilities from urban and rural areas. Of 1570 HCWs who agreed to participate, 1013 (64·5%) provided a urine sampl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc860f1089a88470f7cc4ea411b9384
https://doi.org/10.1017/s0950268813001404

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Effect of HIV-1 and antiretroviral therapy on herpes simplex virus type 2: a prospective study in African women

Autor: P, Mayaud, N, Nagot, I, Konaté, A, Ouedraogo, H A, Weiss, V, Foulongne, M-C, Defer, A, Sawadogo, M, Segondy, P, Van de Perre, Adrien, Sawadogo

Publikováno v: Sexually Transmitted Infections. 84:332-337

To document the natural history of herpes simplex virus type 2 (HSV-2) in relation to HIV and highly active antiretroviral therapy (HAART) in Africa, a longitudinal study was conducted of women in the placebo arms of two randomised controlled trials

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578d8e821d24add631e9a638da7fa7e3
https://doi.org/10.1136/sti.2008.030692

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Roles of clinical and subclinical reactivated herpes simplex virus type 2 infection and human immunodeficiency virus type 1 (HIV-1)-induced immunosuppression on genital and plasma HIV-1 levels

Autor: N, Nagot, A, Ouedraogo, I, Konate, H A, Weiss, V, Foulongne, M C, Defer, A, Sanon, P, Becquart, M, Segondy, A, Sawadogo, P, Van de Perre, P, Mayaud, Philippe, Van de Perre

Publikováno v: The Journal of infectious diseases. 198(2)

Few longitudinal studies have described the interactions between reactivation of herpes simplex virus type 2 (HSV-2) infection (hereafter, "HSV-2 reactivation") and genital and systemic replication of human immunodeficiency virus type 1 (HIV-1).Women

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57293855c0c96dfaa207a314959c1f1c
https://pubmed.ncbi.nlm.nih.gov/18593294

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Longitudinal effect following initiation of highly active antiretroviral therapy on plasma and cervico-vaginal HIV-1 RNA among women in Burkina Faso

Autor: N, Nagot, A, Ouedraogo, H A, Weiss, I, Konate, A, Sanon, M-C, Defer, A, Sawadogo, J-B, Andonaba, R, Vallo, P, Becquart, M, Segondy, P, Mayaud, P, Van de Perre

Publikováno v: Sexually transmitted infections. 84(3)

Background: Highly active antiretroviral therapy (HAART) could decrease HIV-1 transmissibility by reducing genital and plasma HIV-1 RNA. Methods: We evaluated the effect of HAART on genital and plasma HIV-1 RNA in a cohort of 39 antiretroviral-naive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbef9d9ceb9b581ce0ca7cf14c93c928
https://pubmed.ncbi.nlm.nih.gov/18055582

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Impairment of circulating lactoferrin in HIV-1 infection

Autor: M C, Defer, B, Dugas, O, Picard, C, Damais

Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France). 41(3)

Levels of plasma lactoferrin are decreased in HIV-1-infected patients in relation to the progression of the disease. Plasma lactoferrin concentrations were determined using a specific and sensitive enzyme immunoassay. 97 plasma were studied (22 asymp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::06abed314e0b7578569821553f23ab2c
https://pubmed.ncbi.nlm.nih.gov/7580836

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[Role of interleukin-4 in the regulation of nitric oxide production by normal human monocytes]

Autor: M C, Defer, B, Dugas, N, Paul-Eugène, K, Yamaoka, J P, Kolb, C, Damais

Publikováno v: Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 317(11)

Resting normal human monocytes were found to produce small amounts of cGMP in response to IL-4. This production was inhibited in the presence of LNMMA suggesting an association with activation of the NO synthase (NOS) pathway. In addition, this cGMP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3ffd152a6fe4c635448bead3e25f4277
https://pubmed.ncbi.nlm.nih.gov/7882138

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Antilactoferrin autoantibodies associated with HIV infection

Autor: M C, Defer, J Y, Follézou, O, Picard, C, Damais

Publikováno v: Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 317(7)

Sera from 85 HIV-infected patients were tested for the presence of antilactoferrin antibodies (anti-LF Abs) by specific ELISA. Fifty-seven sera were found positive, including sera from asymptomatic (18/28, 64.3%, mean O.D.: 0.27 +/- 0.05) and symptom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a25ee28f89a9e6d1788c0b39c50f21f
https://pubmed.ncbi.nlm.nih.gov/7882152

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