Výsledky vyhledávání - "M. van der Stoep"

FRI0393 BASELINE CHARACTERISTICS OF THE STUDY POPULATION IN ROCCELLA, A PHASE 2 CLINICAL TRIAL EVALUATING THE EFFICACY AND THE SAFETY OF S201086/GLPG1972 IN PATIENTS WITH KNEE OSTEOARTHRITIS

Autor: H. Deckx, A. Lalande, K. Bernard, D. Chimits, Felix Eckstein, K. Muller, S. Grankov, D. Phung, Maria Pueyo, E. van der Aar, M. Van der Stoep, O. Imbert

Publikováno v: Annals of the Rheumatic Diseases. 79:794-795

Background:Osteoarthritis (OA) is a degenerative joint disease involving structural pathology of all joint tissues, and most commonly affecting the knee, hip and hand. Degradation of the cartilage extracellular matrix represents a central feature of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d04d66450ba5bb05912b35d83f515aa
https://doi.org/10.1136/annrheumdis-2020-eular.3442

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Efficacy and safety of s201086/GLPG1972, an ADAMTS-5 inhibitor, in patients with knee osteoarthritis: roccella, a 52-week, randomized, double-blind, dose-ranging phase 2 study

Autor: M. Hochberg, O. Imbert, K. Muller, K. Bernard, S. Hatch, H. Deckx, D. Phung, D. Chimits, Thomas J. Schnitzer, S. Grankov, Felix Eckstein, Maria Pueyo, P.G. Conaghan, M. Van der Stoep, Henning Bliddal, E. van der Aar

Publikováno v: Osteoarthritis and Cartilage. 29:S264

Purpose: To date, no disease-modifying osteoarthritis drugs (DMOADs) have been approved for the treatment of knee osteoarthritis (OA) S201086/GLPG1972 is a potent and selective inhibitor of ADAMTS-5 (a disintegrin and metalloproteinase with thrombosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bccb3d2d92c65025e916d9d436c4f76a
https://doi.org/10.1016/j.joca.2021.02.348

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AB0860 STUDY DESIGN OF ROCCELLA: A PHASE 2 CLINICAL TRIAL WITH A DISEASE-MODIFYING OSTEOARTHRITIS DRUG CANDIDATE GLPG1972/S201086

Autor: M. Wooning, K. Bernard, E. van der Aar, Felix Eckstein, O. Imbert, S. Grankov, M. Van der Stoep, Maria Pueyo, H. Deckx

Publikováno v: Annals of the Rheumatic Diseases. 79:1737-1737

Background:Loss of articular cartilage is one of the major signs of osteoarthritis (OA). Aggrecan, the main proteoglycan component of the extracellular matrix of articular cartilage is cleaved by ADAMTS-5 (A Disintegrin And Metalloproteinase with Thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::659f8c7370acfd60a43dade7934da683
https://doi.org/10.1136/annrheumdis-2020-eular.4418

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Akademický článek

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Hematopoietic alpha 7 nicotinic acetylcholine receptor deficiency increases inflammation and platelet activation status, but does not aggravate atherosclerosis

Autor: P.C.N. Rensen, Sander Kooijman, Jimmy F.P. Berbée, Suzanne J.A. Korporaal, M. Van Eck, M. van der Stoep, Kim L. L. Habets, I Meurs, Bart Lammers, Johannes A. Romijn, L.M. Havekes

Publikováno v: Journal of Thrombosis and Haemostasis, 13(1), 126. Wiley-Blackwell
Journal of thrombosis and haemostasis, 13(1), 126-135. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 1, 13, 126-135
Journal of Thrombosis and Haemostasis, 13(1), 126-135

Summary: Background: The autonomic nervous system attenuates inflammation through activation of the α7 nicotinic acetylcholine receptor (α7nAChR), a pathway termed the cholinergic anti-inflammatory reflex. Interestingly, α7nAChR is expressed on im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef1cc963bb2f99b80d078dd742e7748
https://hdl.handle.net/1887/107802

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Monitoring of clomiphene citrate stimulation by means of plasma 17β-oestradiol determinations and ultrasonographic follicle measurements in in-vitro fertilization treatment cycles

Autor: R.A. Leerentveld, M. van der Stoep, F. H. De Jong, Juriy W. Wladimiroff, A.Th. Alberda, Gerard H. Zeilmaker

Publikováno v: Human Reproduction. 2:187-190

In 57 in-vitro fertilization (IVF) cycles stimulated with clomiphene citrate the relationship between plasma 17 beta-oestradiol (E2) and ultrasonographic measurements of follicle diameter was assessed. Under both monofollicular and multifollicular co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548239279d5971bf2da5a3400595cccb
https://doi.org/10.1093/oxfordjournals.humrep.a136512

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Akademický článek

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Akademický článek

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