Zobrazeno 1 - 10
of 345
pro vyhledávání: '"M. van Santen"'
Autor:
I M A A van Roessel, J E Gorter, B Bakker, M M van den Heuvel-Eibrink, M H Lequin, J van der Lugt, L Meijer, A Y N Schouten-van Meeteren, H M van Santen
Publikováno v:
Endocrine Connections, Vol 13, Iss 10, Pp 1-9 (2024)
Objective: Children with a supratentorial midline low-grade glioma (LGG) may be at risk for impaired bone health due to hypothalamic-pituitary dysfunction, obesity, exposure to multiple treatment modalities, and/or decreased mobility. The presence of
Externí odkaz:
https://doaj.org/article/7ed742e2aa934db7a99ef62ed41a9caf
Autor:
Stephanie van der Leij, Karijn P.M. Suijkerbuijk, Medard F.M. van den Broek, Gerlof D. Valk, Jan Willem Dankbaar, Hanneke M. van Santen
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
ObjectiveImmune checkpoint inhibitors (ICIs) are revolutionary in oncology but may cause immune-related (IR) side effects, such as hypophysitis. Treatment with anti-PD-(L)1, anti-CTLA-4 or anti-CLTA-4/PD-1 may induce hypophysitis, but little is known
Externí odkaz:
https://doaj.org/article/73f1eed923fd49ac9969997611f02158
Autor:
Ashwathi Puravankara Menon, Helena Villanueva, Daniel Meraviglia-Crivelli, Hisse M. van Santen, Joschka Hellmeier, Angelina Zheleva, Francesca Nonateli, Timo Peters, Tassilo L.A. Wachsmann, Mercedes Hernandez-Rueda, Johannes B. Huppa, Gerhard J. Schütz, Eva Sevcsik, Beatriz Moreno, Fernando Pastor
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102198- (2024)
The CD3/T cell receptor (TCR) complex is responsible for antigen-specific pathogen recognition by T cells, and initiates the signaling cascade necessary for activation of effector functions. CD3 agonistic antibodies are commonly used to expand T lymp
Externí odkaz:
https://doaj.org/article/6c3ef753dfa94901b0ef2480454cb96e
Autor:
Maria Otth, Katrin Scheinemann, Thankamma Ajithkumar, Kristian Aquilina, Shivaram Avula, Hoong-Wei Gan, Geert O. Janssens, Jurgen Lemiere, Giovanni Morana, Enrico Opocher, Stefan M. Pfister, Giorgio Porro, Felix Sahm, Ulrich-Wilhelm Thomale, Michelle van Egmond-Ebbeling, Hanneke M. van Santen, Barry Pizer, Stefan Rutkowski
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100166- (2024)
Tumours of the central nervous system (CNS) represent the most common group of solid tumours in children and adolescents up to the age of 18 years. They comprise several biological entities, subgroups, and subtypes. These subtypes and additional fact
Externí odkaz:
https://doaj.org/article/725bd3ec24ad47f99a354342f9261167
Publikováno v:
Endocrine Connections, Vol 12, Iss 10, Pp 1-12 (2023)
Objective: Hypothalamic dysfunction is a rare condition and can be encountered in patients who have been diagnosed or treated for a suprasellar brain tumor. Due to its rarity, the signs and symptoms of hypothalamic dysfunction may be difficult to rec
Externí odkaz:
https://doaj.org/article/d777a4ed86844370bf39976983c07dd0
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
Children with acquired hypothalamic obesity, e.g. following treatment for pediatric craniopharyngioma are at great risk for metabolic syndrome, cardiovascular health problems and premature mortality. Treatment for acquired hypothalamic obesity has th
Externí odkaz:
https://doaj.org/article/f68c5df2fc4946c09107afe2132b73d5
Autor:
S C Clement, W E Visser, C A Lebbink, D Albano, H L Claahsen-van der Grinten, A Czarniecka, R P Dias, M P Dierselhuis, I Dzivite-Krisane, R Elisei, A Garcia-Burillo, L Izatt, C Kanaka-Gantenbein, H Krude, L Lamartina, K Lorenz, M Luster, R Navardauskaitė, M Negre Busó, K Newbold, R P Peeters, G Pellegriti, A Piccardo, A L Priego, A Redlich, L de Sanctis, M Sobrinho-Simões, A S P van Trotsenburg, F A Verburg, M Vriens, T P Links, S F Ahmed, H M van Santen
Publikováno v:
Endocrine Connections, Vol 12, Iss 3, Pp 1-9 (2023)
Background: Although differentiated thyroid carcinoma (DTC) is the most freq uent endocrine pediatric cancer, it is rare in childhood and adolescence. While tumor persistence and recurrence are not uncommon, mortality remains extremely low. Compli
Externí odkaz:
https://doaj.org/article/1f0e1d2e0380462fb7388c8ed45cda3b
Autor:
Evelien de Vos-Kerkhof, Dennis R. Buis, Maarten H. Lequin, Carlien A. Bennebroek, Eleonora Aronica, Esther Hulleman, Nitash Zwaveling-Soonawala, Hanneke M. van Santen, Antoinette Y. N. Schouten-van Meeteren
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
We present the case of a 15-year-old girl, with a fifth cystic progression of an adamantinomatous craniopharyngioma after multiple surgeries and previous local radiotherapy. She had severe visual impairment, panhypopituitarism including diabetes insi
Externí odkaz:
https://doaj.org/article/f724c632f26640eaa443f4ab9a56aaef
Autor:
Chantal A Lebbink, Agnieszka Czarniecka, Renuka P Dias, Rossella Elisei, Louise Izatt, Heiko Krude, Kerstin Lorenz, Markus Luster, Kate Newbold, Arnoldo Piccardo, Manuel Sobrinho-Simões, Toru Takano, A S Paul van Trotsenburg, Frederik A Verburg, Hanneke M van Santen, Thera P Links
Publikováno v:
European Thyroid Journal, Vol 11, Iss 6, Pp 1-40 (2023)
At present, no European recommendations for the management of pediatric thyroid nodules and differentiated thyroid carcinoma (DTC) exist. Differe nces in clinical, molecular, and pathological characteristics between pediatric and adult DTC emphasize
Externí odkaz:
https://doaj.org/article/54df81e109af46dc835dc5782cc169e1
Publikováno v:
Endocrine Connections, Vol 12, Iss 1, Pp 1-7 (2022)
Childhood cancer survivors are at risk for developing endocrine disorders, including deficits in growth hormone, thyroid hormone and sex hormones. Th e influence these hormones have on cell growth and metabolism has raised concerns regarding the safe
Externí odkaz:
https://doaj.org/article/f9f643a612284146ada09074265d92c9