Zobrazeno 1 - 10
of 733
pro vyhledávání: '"M. van Kleef"'
Autor:
Katrien C. K. Poelaert, Regina G. D. M. van Kleef, Mengying Liu, Arno van Vliet, Heyrhyoung Lyoo, Lora-Sophie Gerber, Yoshiki Narimatsu, Christian Büll, Henrik Clausen, Erik de Vries, Remco H. S. Westerink, Frank J. M. van Kuppeveld
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Enterovirus D68 (EV-D68) is an emerging pathogen associated with mild to severe respiratory disease. Since 2014, EV-D68 is also linked to acute flaccid myelitis (AFM), causing paralysis and muscle weakness in children. However, it remains un
Externí odkaz:
https://doaj.org/article/aa3c5d37a7934c0eacc5a321ef01fbd8
Autor:
Monique E. A. M. van Kleef, Frank L. J. Visseren, Jan Westerink, Michiel L. Bots, Peter J. Blankestijn, Yolanda van der Graaf, Wilko Spiering
Publikováno v:
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Satisfactory tools to preclude low-risk patients from intensive diagnostic testing for primary aldosteronism (PA) are lacking. Therefore, we aimed to develop a decision tool to determine which patients with difficult-to-control hy
Externí odkaz:
https://doaj.org/article/8558895432ba46f0a3adecd589bdfcda
Autor:
Monique E. A. M. van Kleef, Karsten Heusser, André Diedrich, P. Liam Oey, Jens Tank, Jens Jordan, Peter J. Blankestijn, Bryan Williams, Wilko Spiering
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Background First in human studies suggest that endovascular baroreflex amplification (EVBA) lowers blood pressure (BP). To explore potential mechanisms for BP reduction, this study examines the effects of EVBA on muscle sympathetic nerve activity (MS
Externí odkaz:
https://doaj.org/article/edeed791535346549be1283a97076f5f
Autor:
Lisa Bauer, Roberto Manganaro, Birgit Zonsics, Daniel L Hurdiss, Marleen Zwaagstra, Tim Donselaar, Naemi G E Welter, Regina G D M van Kleef, Moira Lorenzo Lopez, Federica Bevilacqua, Thamidur Raman, Salvatore Ferla, Marcella Bassetto, Johan Neyts, Jeroen R P M Strating, Remco H S Westerink, Andrea Brancale, Frank J M van Kuppeveld
Publikováno v:
PLoS Biology, Vol 18, Iss 11, p e3000904 (2020)
There is a great need for antiviral drugs to treat enterovirus (EV) and rhinovirus (RV) infections, which can be severe and occasionally life-threatening. The conserved nonstructural protein 2C, which is an AAA+ ATPase, is a promising target for drug
Externí odkaz:
https://doaj.org/article/89e23fb98cb14c2cbff74c8336bc7f45
Autor:
Eline H. Groenland, Monique E. A. M. van Kleef, Jeroen Hendrikse, Wilko Spiering, Jeroen C. W. Siero
Publikováno v:
Frontiers in Neuroimaging. 1
BackgroundEndovascular baroreflex amplification (EVBA) by implantation of the MobiusHD is hypothesized to lower blood pressure by decreasing sympathetic activity through the mechanism of the baroreflex. In the present exploratory study we investigate
Publikováno v:
JACC. Cardiovascular interventions. 15(11)
Autor:
Kim C M van der Elst, Michiel L. Bots, Monique E. A. M. van Kleef, Eline H. Groenland, Frank L.J. Visseren, Wilko Spiering
Publikováno v:
Hypertension. 77:85-93
Biochemical drug screening by liquid chromatography-tandem mass spectrometry in plasma is an accurate method for the quantification of plasma concentrations of antihypertensive medications in patients with hypertension. Trough concentrations could po
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Autor:
Jens Jordan, Jens Tank, Wilko Spiering, Peter J. Blankestijn, Bryan Williams, André Diedrich, Karsten Heusser, P. Liam Oey, Monique E. A. M. van Kleef
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259826 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259826 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
Background First in human studies suggest that endovascular baroreflex amplification (EVBA) lowers blood pressure (BP). To explore potential mechanisms for BP reduction, this study examines the effects of EVBA on muscle sympathetic nerve activity (MS
Autor:
Monique E A M, van Kleef, Chandan M, Devireddy, Jan, van der Heyden, Mark C, Bates, George L, Bakris, Gregg W, Stone, Bryan, Williams, Wilko, Spiering
Publikováno v:
JACC. Cardiovascular interventions. 15(3)
The aim of this study was to evaluate the long-term (3-year) safety and effectiveness of endovascular baroreflex amplification (EVBA) from both the European and American CALM-FIM cohorts.The CALM-FIM study demonstrated that EVBA in patients with resi