GaitSmart motion analysis compared to commonly used function outcome measures in the IMI-APPROACH knee osteoarthritis cohort

Autor: Eefje M. van Helvoort, D. Hodgins, Simon C. Mastbergen, Anne C. A. Marijnissen, M. Kloppenburg, Fransisco J. Blanco, Ida K. Haugen, F. Berenbaum, Floris P. J. G. Lafeber, Paco M. J. Welsing

Publikováno v: PLoS ONE, Vol 17, Iss 3 (2022)

Background There are multiple measures for assessment of physical function in knee osteoarthritis (OA), but each has its strengths and limitations. The GaitSmart® system, which uses inertial measurement units (IMUs), might be a user-friendly and obj

Externí odkaz: https://doaj.org/article/f2ef08dd3f1c41a396812ae957b0af10

Canine IL4-10 fusion protein provides disease modifying activity in a canine model of OA; an exploratory study.

Autor: E M van Helvoort, J Popov-Celeketic, N Eijkelkamp, K Coeleveld, M A Tryfonidou, C D Wijne, C E Hack, F P J G Lafeber, S C Mastbergen

Publikováno v: PLoS ONE, Vol 14, Iss 7, p e0219587 (2019)

ObjectiveAn ideal disease modifying osteoarthritis drug (DMOAD) has chondroprotective, anti-inflammatory, and analgesic effects. This study describes the production and characterization of a canine IL4-10 fusion protein (IL4-10 FP) and evaluates its

Externí odkaz: https://doaj.org/article/1b11265c96bc4c6c89a1c1f3cdda314d

Low-Frequency Electromagnetic Shielding and Scattering of Multiple Cylindrical Shells

Autor: Dick W. Harberts, Mark J. A. M. van Helvoort

Publikováno v: IEEE Transactions on Electromagnetic Compatibility. 63:46-56

Emerging additive manufacturing methods facilitate the creation of enclosures with tailor-made shielding and scattering performance by using multiple conductive and dielectric layers. For a first analysis an elongated housing, with a cross-section sm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68da02078e6b776fa4bc936b53959671
https://doi.org/10.1109/temc.2020.3011757

Expression of granulocyte macrophage-colony stimulating factor and its receptor in the synovium of osteoarthritis patients is negatively correlated with pain

Autor: Simon C. Mastbergen, Floris P J G Lafeber, Eefje M van Helvoort, Niels Eijkelkamp

Publikováno v: Rheumatology. 59:3452-3457

Objectives The crosstalk between the immune and nervous system in the regulation of OA pain is increasingly becoming evident. GM-CSF signals in both systems and might be a new treatment target to control OA pain. Anti GM-CSF treatment has analgesic e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c84d7852142023c7a0a313e5288336
https://doi.org/10.1093/rheumatology/keaa199

Relationship between motion, using the GaitSmart (TM) system, and radiographic knee osteoarthritis: an explorative analysis in the IMI-APPROACH cohort

Autor: Diana Hodgins, Floris P J G Lafeber, Anne Karien Marijnissen, Francis Berenbaum, Margreet Kloppenburg, Eefje M van Helvoort, Ida K. Haugen, Francisco J. Blanco, Simon C. Mastbergen, M. Loef, Paco M J Welsing, Hans Guehring

Publikováno v: Rheumatology (Oxford, England)
Rheumatology
Rheumatology, Oxford University Press (OUP), 2021, 60 (8), pp.3588-3597. ⟨10.1093/rheumatology/keaa809⟩
Rheumatology, 60(8), 3588-3597. OXFORD UNIV PRESS
RUC. Repositorio da Universidade da Coruña
instname
Rheumatology, 2021, 60 (8), pp.3588-3597. ⟨10.1093/rheumatology/keaa809⟩

Objectives To assess underlying domains measured by GaitSmartTMparameters and whether these are additional to established OA markers including patient reported outcome measures (PROMs) and radiographic parameters, and to evaluate if GaitSmart analysi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea3165e32acdbdb731d9f1987818748
https://hdl.handle.net/1887/3458826