Zobrazeno 1 - 10
of 27
pro vyhledávání: '"M. Zinna"'
Autor:
Andy Göbel, Valentina M. Zinna, Stefania Dell’Endice, Nikolai Jaschke, Jan Dominik Kuhlmann, Pauline Wimberger, Tilman D. Rachner
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background Ovarian cancer remains the most fatal gynecological malignancy. Current therapeutic options are limited due to late diagnosis in the majority of the cases, metastatic spread to the peritoneal cavity and the onset of chemo-resistan
Externí odkaz:
https://doaj.org/article/9646a631756b47db9076b98eec6dd654
Autor:
Martin Kräter, Angela Jacobi, Oliver Otto, Stefanie Tietze, Katrin Müller, David M. Poitz, Sandra Palm, Valentina M. Zinna, Ulrike Biehain, Manja Wobus, Triantafyllos Chavakis, Carsten Werner, Jochen Guck, Martin Bornhauser
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract The bone marrow (BM) microenvironment provides critical physical cues for hematopoietic stem and progenitor cell (HSPC) maintenance and fate decision mediated by cell-matrix interactions. However, the mechanisms underlying matrix communicati
Externí odkaz:
https://doaj.org/article/3edcabb0611b42bd9fb7a863b22e1766
Autor:
Paul Petrus, Jacob G. Smith, Kevin B. Koronowski, Siwei Chen, Tomoki Sato, Carolina M. Greco, Thomas Mortimer, Patrick-Simon Welz, Valentina M. Zinna, Kohei Shimaji, Marlene Cervantes, Daniela Punzo, Pierre Baldi, Pura Muñoz-Cánoves, Paolo Sassone-Corsi, Salvador Aznar Benitah
Publikováno v:
Science advances, vol 8, iss 26
Life on Earth anticipates recurring 24-hour environmental cycles via genetically encoded molecular clocks active in all mammalian organs. Communication between these clocks controls circadian homeostasis. Intertissue communication is mediated, in par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8459b22b8bf6c1e51e626fa03be29a05
https://escholarship.org/uc/item/41g4628h
https://escholarship.org/uc/item/41g4628h
Autor:
Paloma, Solá, Valentina M, Zinna
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2482
Epidermal and interfollicular stem cell proliferation and differentiation are controlled in a circadian manner, in order to anticipate the daily environmental challenges. For this reason, examining the circadian transcriptome of interfollicular stem
Autor:
Pauline Wimberger, Andy Göbel, Valentina M. Zinna, Nikolai Jaschke, Tilman D. Rachner, Stefania Dell'Endice, Jan Dominik Kuhlmann
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-17 (2020)
BMC Cancer
BMC Cancer
BackgroundOvarian cancer remains the most fatal gynecological malignancy. Current therapeutic options are limited due to late diagnosis in the majority of the cases, metastatic spread to the peritoneal cavity and the onset of chemo-resistance. Thus,
Autor:
Thomas Mortimer, Valentina M. Zinna, Carmelo Laudanna, Paul Petrus, Kevin B. Koronowski, Jacob G. Smith, Carolina M. Greco, Elisa García-Lara, Arun Kumar, Mireia Vaca-Dempere, Oleg Deryagin, Stephen Forrow, Paolo Sassone-Corsi, Patrick-Simon Welz, Pura Muñoz-Cánoves, Salvador Aznar Benitah
In mammals, an integrated network of molecular oscillators drives daily rhythms of tissue-specific homeostatic processes. This network is required for maintaining health and can be compromised by physiological aging, disease, and lifestyle choices. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e68fd039a5ae2e6f8a866f31b9f70c3
https://doi.org/10.1101/2022.01.26.477844
https://doi.org/10.1101/2022.01.26.477844
Autor:
Paloma Solá, Valentina M. Zinna
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622483
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b40ac601289be7503340b5a0d0377e37
https://doi.org/10.1007/978-1-0716-2249-0_16
https://doi.org/10.1007/978-1-0716-2249-0_16
Autor:
Patrick-Simon Welz, Roberta Carriero, Paolo Kunderfranco, Selma Masri, Siwei Chen, Arun Kumar, Pierre Baldi, Thomas Mortimer, Kenneth A. Dyar, Kevin B. Koronowski, Jacob G. Smith, Jiejun Shi, Oleg Deryagian, Salvador Aznar Benitah, Wei Li, Kohei Shimaji, José Manuel Monroy Kuhn, Paul Petrus, Muntaha Samad, Valentina M. Zinna, Carolina Magdalen Greco, Sung Kook Chun, Mireia Vaca-Dempere, Cassandra Van, Pura Muñoz-Cánoves, Paolo Sassone-Corsi, Marcus M. Seldin, Tomoki Sato, Dominik Lutter
Publikováno v:
Science Advances
Science advances, vol 7, iss 39
Sci. Adv. 7:eabi7828 (2021)
Science advances, vol 7, iss 39
Sci. Adv. 7:eabi7828 (2021)
Description
The inner workings of the clock system rely on communicating signals between distal tissues to maintain daily metabolism.
The mammalian circadian clock, expressed throughout the brain and body, controls daily metabolic homeostas
The inner workings of the clock system rely on communicating signals between distal tissues to maintain daily metabolism.
The mammalian circadian clock, expressed throughout the brain and body, controls daily metabolic homeostas
Autor:
Ferrán Aragón, Kenichiro Kinouchi, Paolo Sassone-Corsi, Aikaterini Symeonidi, Neus Prats, Jacob G. Smith, Andrés Hidalgo, Valentina M. Zinna, Patrick Simon Welz, Andrés Castellanos, Kevin B. Koronowski, Salvador Aznar Benitah, Georgiana Crainiciuc, Inés Marín Guillén, Stephen Furrow, Juan Martín Caballero
Publikováno v:
Cell, vol 177, iss 6
Cell
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Cell
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Summary Circadian rhythms control organismal physiology throughout the day. At the cellular level, clock regulation is established by a self-sustained Bmal1-dependent transcriptional oscillator network. However, it is still unclear how different tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9e7c997352b2c0f2ecb5a0aa03fc3c
https://escholarship.org/uc/item/7t2173k6
https://escholarship.org/uc/item/7t2173k6
Autor:
Andy Göbel, Andrew J. Browne, Valentina M. Zinna, Stefanie Thiele, Tilman D. Rachner, Lorenz C. Hofbauer, Martina Rauner
Publikováno v:
Cancer Letters. 375:162-171
Amino-bisphosphonates are antiresorptive drugs for the treatment of osteolytic bone metastases, which are frequently caused by breast and other solid tumors. Like statins, amino-bisphosphonates inhibit the mevalonate pathway. Direct anti-tumor effect