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Akademický článek

Intrauterine infusion of a pathogenic bacterial cocktail is associated with the development of clinical metritis in postpartum multiparous Holstein cows

Autor: J.C.C. Silva, L.C. Siqueira, M.X. Rodrigues, M. Zinicola, P. Wolkmer, B. Pomeroy, R.C. Bicalho

Publikováno v: Journal of Dairy Science, Vol 106, Iss 1, Pp 607-623 (2023)

ABSTRACT: Metritis is a uterine disorder common in dairy cattle caused by bacterial infection, with greater incidence in the early postpartum period. The disease causes delayed uterine involution, with a fetid, watery, red-brown discharge, with anima

Externí odkaz: https://doaj.org/article/da8bba0bfa314bc391354a6d27abece1

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Akademický článek

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Recombinant protein subunit vaccine reduces puerperal metritis incidence and modulates the genital tract microbiome

Autor: E.B.S. Meira, R. Linwood, L. Bringhenti, C.H. Higgins, Marjory Xavier Rodrigues, J.C.C. Silva, Rodrigo C. Bicalho, H. Korzec, M. Zinicola, R.D. Ellington-Lawrence, Yongqiang Yang

Publikováno v: Journal of Dairy Science. 103:7364-7376

The objective of this study was to evaluate the efficacy of 3 vaccine formulations containing proteins (FimH, leukotoxin, and pyolysin), inactivated whole cells (Escherichia coli, Fusobacterium necrophorum, and Trueperella pyogenes), or both, in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82e2ab7a42d4ff461cd5cc32e203c2f
https://doi.org/10.3168/jds.2019-17006

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Intrauterine infusion of a pathogenic bacterial cocktail is associated with the development of clinical metritis in postpartum multiparous Holstein cows

Autor: J.C.C. Silva, L.C. Siqueira, M.X. Rodrigues, M. Zinicola, P. Wolkmer, B. Pomeroy, R.C. Bicalho

Publikováno v: Journal of dairy science. 106(1)

Metritis is a uterine disorder common in dairy cattle caused by bacterial infection, with greater incidence in the early postpartum period. The disease causes delayed uterine involution, with a fetid, watery, red-brown discharge, with animals present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebcb2015c59fd7622bfba9798ef972da
https://pubmed.ncbi.nlm.nih.gov/36400620

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Effects of recombinant bovine interleukin-8 (rbIL-8) treatment on health, metabolism, and lactation performance in Holstein cattle IV: Insulin resistance, dry matter intake, and blood parameters

Autor: L. Bringhenti, C. P. Batista, S. P. McDonough, Fabio S. Lima, M. Zinicola, E.B.S. Meira, Rodrigo C. Bicalho

Publikováno v: Journal of Dairy Science. 102:10340-10359

We have shown in 2 independent studies that cows who received recombinant bovine interleukin-8 (rbIL-8) administered intrauterinely shortly after parturition have a significant and long-lasting increase in milk yield. In the present study, we hypothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55127a418c0e0904b6aa15672e2cf34c
https://doi.org/10.3168/jds.2019-16337

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Effect of pegbovigrastim administration on the microbiome found in the vagina of cows postpartum

Autor: C.H. Higgins, Soo Jin Jeon, Rodrigo C. Bicalho, Klibs N. Galvão, H. Korzec, M. Zinicola

Publikováno v: Journal of Dairy Science. 102:3439-3451

The objective of this study was to evaluate the effect of pegbovigrastim (PEG) treatment of peripartum Holstein cows on the microbiome found in the vagina postpartum using sequencing of the 16S rRNA gene. A subset of cows was randomly sampled from a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db39bbe5b4091c0833249778aba9851
https://doi.org/10.3168/jds.2018-15783

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Effects of recombinant bovine interleukin-8 (rbIL-8) treatment on health, metabolism, and lactation performance in Holstein cattle I: Production and functional characterization of rbIL-8 in vitro and in vivo

Autor: A.G.V. Teixeira, Rodrigo C. Bicalho, M. Zinicola, Fabio S. Lima, Vinicius Machado, M. R. Xavier, C. Narbus, H. Higgins, M.L.S. Bicalho

Publikováno v: Journal of dairy science. 102(11)

In the present study, we standardized processes of cloning and purification of recombinant bovine interleukin-8 (rbIL-8) from bacterial culture and assessed its biological activity in Holstein cattle. Plasmid containing a subclone of bovine IL-8 was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb6718749a4006e5652bde0824ee11f
https://pubmed.ncbi.nlm.nih.gov/31495610

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Effects of recombinant bovine interleukin-8 (rbIL-8) treatment on health, metabolism, and lactation performance in Holstein cattle III: Administration of rbIL-8 induces insulin resistance in bull calves

Autor: P.R. Menta, M. Zinicola, Rodrigo C. Bicalho, B.L. Ribeiro, Yves R. Boisclair

Publikováno v: Journal of dairy science. 102(11)

Our previous work has suggested that recombinant bovine interleukin-8 (rbIL-8) treatment might influence cow metabolism. Therefore, this study was conducted to initially assess the effects of systemic administration of rbIL-8 on response to a glucose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b1e7937b8e792071fce2b07b758fb2
https://pubmed.ncbi.nlm.nih.gov/31495622

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