Zobrazeno 1 - 10
of 987
pro vyhledávání: '"M. Zaiss"'
Autor:
Brenda Krishnacoumar, Martin Stenzel, Hilal Garibagaoglu, Yasunori Omata, Rachel L. Sworn, Thea Hofmann, Natacha Ipseiz, Magdalena A. Czubala, Ulrike Steffen, Antonio Maccataio, Cornelia Stoll, Christina Böhm, Martin Herrmann, Stefan Uderhardt, Robert H. Jenkins, Philip R. Taylor, Anika Grüneboom, Mario M. Zaiss, Georg Schett, Gerhard Krönke, Carina Scholtysek
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Efficient cellular fusion of mononuclear precursors is the prerequisite for the generation of fully functional multinucleated bone-resorbing osteoclasts. However, the exact molecular factors and mechanisms controlling osteoclast fusion remai
Externí odkaz:
https://doaj.org/article/a3409e48ebd5446880ba7bab830dfe79
Autor:
Morten S. Hansen, Kaja Madsen, Maria Price, Kent Søe, Yasunori Omata, Mario M. Zaiss, Caroline M. Gorvin, Morten Frost, Alexander Rauch
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract Enhanced osteoclastogenesis and osteoclast activity contribute to the development of osteoporosis, which is characterized by increased bone resorption and inadequate bone formation. As novel antiosteoporotic therapeutics are needed, understa
Externí odkaz:
https://doaj.org/article/07cd662fb2b44d048356f763ceaac820
Autor:
Vugar Azizov, Michel Hübner, Michael Frech, Jörg Hofmann, Marketa Kubankova, Dennis Lapuente, Matthias Tenbusch, Jochen Guck, Georg Schett, Mario M. Zaiss
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107230- (2023)
Summary: Alcohol is among the most widely consumed dietary substances. Excessive alcohol consumption damages the liver, heart, and brain. Alcohol also has strong immunoregulatory properties. Here, we report how alcohol impairs T cell function via ace
Externí odkaz:
https://doaj.org/article/4f38ace1511c4f95970755bb2e6a147e
Autor:
Ivana Steiner, Teresita del N.J. Flores-Tellez, Renaud Mevel, Amin Ali, Pengbo Wang, Pieta Schofield, Caron Behan, Nicholas Forsythe, Garry Ashton, Catherine Taylor, Ian G. Mills, Pedro Oliveira, Simon S. McDade, Dietmar M. Zaiss, Ananya Choudhury, Georges Lacaud, Esther Baena
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112377- (2023)
Summary: The emergence of castration-resistant prostate cancer remains an area of unmet clinical need. We recently identified a subpopulation of normal prostate progenitor cells, characterized by an intrinsic resistance to androgen deprivation and ex
Externí odkaz:
https://doaj.org/article/ea2b525372434ee5b0059bdaa9e2fe69
Autor:
R. Bartsch, N. Harbeck, D. Wrobel, M. Zaiss, J. Terhaag, D. Guth, A. Distelrath, R. Wuerstlein, M.-O. Zahn, D. Lüftner, M. Schwitter, M. Balic, C. Jackisch, V. Müller, G. Rinnerthaler, M. Schmidt, K. Zaman, T. Schinköthe, M. Gorray, U. Breitenstein
Publikováno v:
Breast, Vol 68, Iss , Pp S20-S21 (2023)
Externí odkaz:
https://doaj.org/article/c524022cbe37407da8000e49a3ec5de6
Autor:
Fabian Schälter, Kerstin Dürholz, Laura Bucci, Gerd Burmester, Roberto Caporali, Camille Figuereido, Jaime Fogagnolo Cobra, Bernhard Manger, Mario M. Zaiss, Georg Schett
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-6 (2021)
Abstract Background To investigate whether methotrexate treatment may affect the susceptibility to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods Clinical assessment of symptoms, SARS-CoV-2 RNA, and anti-SARS-CoV
Externí odkaz:
https://doaj.org/article/76631b1133cb4fc88d57baf5ab3bc0cc
Autor:
Kerstin Dürholz, Eva Schmid, Michael Frech, Vugar Azizov, Nadine Otterbein, Sébastien Lucas, Manfred Rauh, Georg Schett, Heiko Bruns, Mario M. Zaiss
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Rheumatoid arthritis (RA) is associated with an increased risk for cardiovascular events driven by abnormal platelet clotting effects. Platelets are produced by megakaryocytes, deriving from megakaryocyte erythrocyte progenitors (MEP) in the bone mar
Externí odkaz:
https://doaj.org/article/f698914e2b054ddaa852268ec18addb1
Autor:
Yasunori Omata, Hiroyuki Okada, Steffen Uebe, Naohiro Izawa, Arif B. Ekici, Kerstin Sarter, Taku Saito, Georg Schett, Sakae Tanaka, Mario M. Zaiss
Publikováno v:
JBMR Plus, Vol 6, Iss 7, Pp n/a-n/a (2022)
ABSTRACT Bone turnover is finely tuned by cells in the bone milieu, including osteoblasts, osteoclasts, and osteocytes. Osteoclasts are multinucleated giant cells with a bone‐resorbing function that play a critical role in regulating skeletal homeo
Externí odkaz:
https://doaj.org/article/6cbfdb6971e440e7af6ee572be7528b2
Autor:
Alexander Duscha, Tobias Hegelmaier, Kerstin Dürholz, Christiane Desel, Ralf Gold, Mario M. Zaiss, Aiden Haghikia
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 15 (2022)
Background: The impact of the gut and its microbiota are increasingly appreciated in health and disease. Short-chain fatty acids (SCFAs) are among the main metabolites synthesized from bacterial fermentation. Recently, we showed the anti-inflammatory
Externí odkaz:
https://doaj.org/article/9e508d4f13ec41f6877ff8b80e296831
Autor:
David Simon, Koray Tascilar, Gerhard Krönke, Arnd Kleyer, Mario M. Zaiss, Franz Heppt, Christine Meder, Raja Atreya, Entcho Klenske, Peter Dietrich, Abdullah Abdullah, Thorsten Kliem, Giulia Corte, Harriet Morf, Moritz Leppkes, Andreas E. Kremer, Andreas Ramming, Milena Pachowsky, Florian Schuch, Monika Ronneberger, Stefan Kleinert, Clara Maier, Axel J. Hueber, Karin Manger, Bernhard Manger, Carola Berking, Matthias Tenbusch, Klaus Überla, Michael Sticherling, Markus F. Neurath, Georg Schett
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Cytokine storm seems to be a common feature of severe COVID-19 pathology. Here, the authors show a reduced rate of SARS-CoV2 positivity in a large population of patients with immune-mediated inflammatory diseases if they are already being treated wit
Externí odkaz:
https://doaj.org/article/e2e3c987d9e84ccb9b7c66bef2e582d6