Zobrazeno 1 - 10 of 19 pro vyhledávání: '"M. Z. Zdzienicka"'
1
Cellular response of X-ray sensitive hamster mutant cell lines to gemcitabine, cisplatin and 5-fluorouracil
Autor: Lukas J.A. Stalpers, M. Z. Zdzienicka, Hans M. Rodermond, G.J. Peters, C. van Bree, Jaap Haveman, Nicolaas A. P. Franken, N. Castro Kreder
Publikováno v: Oncology reports, 12(1), 187-192. Spandidos Publications
Europe PubMed Central
Five mutant Chinese hamster cell lines deficient in DNA repair with the corresponding parental cell lines were used to determine their sensitivity to cisplatin, 5-fluorouracil and gemcitabine. The mutations in the cell lines led to defective single s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d140a350c106533c41c2702ad570c059
https://pubmed.ncbi.nlm.nih.gov/15201982
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2
Cellular response to pulsed low-dose rate irradiation in X-ray sensitive hamster mutant cell lines
Autor: C. van Bree, Nicolaas A. P. Franken, M. Z. Zdzienicka, Hans M. Rodermond, N. Castro Kreder, Jaap Haveman, R. ten Cate
Publikováno v: Journal of radiation research, 45(3), 385-391. Japan Radiation Research Society
Journal of Radiation Research, 45(3), 385-391. Japan Radiation Research Society
The role of DNA repair mechanisms in the cellular response to low dose rate (LDR) irradiation was studied with the aim to gain insight in the process of sublethal damage (SLD) repair. Chinese hamster cell lines mutated in either DNA single strand bre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbdc9f807958ee25b1fc66b7b097a48
https://pure.amc.nl/en/publications/cellular-response-to-pulsed-lowdose-rate-irradiation-in-xray-sensitive-hamster-mutant-cell-lines(801a8f86-4e5b-4e16-a507-392289ec1a7b).html
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3
Induction of DNA breaks and apoptosis in crosslink-hypersensitive V79 cells by the cytostatic drug beta-D-glucosyl-ifosfamide mustard
Autor: A Ritter, J Lips, M Z Zdzienicka, Manfred Wiessler, Bernd Kaina, R Becker, B Bertram, Uta Eichhorn
Publikováno v: British Journal of Cancer
To study molecular aspects of cytotoxicity of the anticancer drug β-D-glucose-ifosfamide mustard we investigated the potential of the agent to induce apoptosis and DNA breakage. Since β-D-glucose-ifosfamide mustard generates DNA interstrand crossli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460868ca606e2bdc6f70789c32f57709
https://pubmed.ncbi.nlm.nih.gov/11857024
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6
Human chromosome 21 determines growth factor dependence in human/mouse B-cell hybridomas
Autor: S B, Ebeling, H M, Bos, R, Slater, W J, Overkamp, A P, Cuthbert, R F, Newbold, M Z, Zdzienicka, L A, Aarden
Publikováno v: Cancer research. 58(13)
Interleukin 6 (IL-6) serves as a growth factor for mouse plasmacytomas. As a model for IL-6-mediated growth of plasmacytomas, we study IL-6-dependent B-cell hybridomas, which can be generated through fusion of B lymphocytes with a plasmacytoma cell l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c189af5cec3ba12f65e032702920cc6a
https://pubmed.ncbi.nlm.nih.gov/9661903
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7
Molecular processes and radiosensitivity
Autor: M. Z. Zdzienicka
Publikováno v: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. 173(9)
DNA double-strand breaks (DSB) are the most genotoxic lesions induced by ionizing radiation. At least 2 different pathways for DSB repair have been identified, homologous and non-homologous recombination.Studies on X-ray-sensitive mutants have led to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb714937c40c5eab96a9f2d6d2730009
https://pubmed.ncbi.nlm.nih.gov/9325443
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8
A gene that regulates DNA replication in response to DNA damage is located on human chromosome 4q
Autor: G W, Verhaegh, W, Jongmans, N G, Jaspers, A T, Natarajan, M, Oshimura, P H, Lohman, M Z, Zdzienicka
Publikováno v: American journal of human genetics. 57(5)
Inhibition of replicative DNA synthesis following gamma-irradiation is observed in eukaryotic cells but is defective in cells derived from patients with the cancer-prone inherited disorder ataxia-telangiectasia (A-T) and in A-T-like Chinese hamster c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6749edd264742c48482873c1bbcdc78d
https://pubmed.ncbi.nlm.nih.gov/7485160
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9
Complementation analysis of the murine scid cell line
Autor: M Z, Zdzienicka, W, Jongmans, M, Oshimura, A, Priestley, G F, Whitmore, P A, Jeggo
Publikováno v: Radiation research. 143(3)
It has been shown that several X-ray-sensitive Chinese hamster cell mutants defective in repair of DNA double-strand breaks (DSBs) are also impaired in the process of V(D)J recombination. The hamster mutants with this phenotype represent three distin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::511550ab04441998186d0402d11e558c
https://pubmed.ncbi.nlm.nih.gov/7652160
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10
A new complementation group of mitomycin C-hypersensitive Chinese hamster cell mutants that closely resembles the phenotype of fanconi anemia cells
Autor: P, Telleman, W J, Overkamp, N, van Wessel, K, Studzian, L, Wetselaar, A T, Natarajan, M Z, Zdzienicka
Publikováno v: Cancer research. 55(15)
Three Mitomycin C (MMC)-hypersensitive mutants (CL-V1B, CL-V5B, and CL-V101B) were isolated from Chinese hamster V79B cells by the replica plating technique. In comparison to the parental cell line, CL-V1B, CL-V5B, and CL-V101B show about a 22-, 32-,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::313461ca181739cc0d90a664005d7ac4
https://pubmed.ncbi.nlm.nih.gov/7614481
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