Zobrazeno 1 - 10
of 3 781
pro vyhledávání: '"M. Yeomans"'
Autor:
Mehrana R. Nejad, Liam J. Ruske, Molly McCord, Jun Zhang, Guanming Zhang, Jacob Notbohm, Julia M. Yeomans
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract In tissue formation and repair, the epithelium undergoes complex patterns of motion driven by the active forces produced by each cell. Although the principles governing how the forces evolve in time are not yet clear, it is often assumed tha
Externí odkaz:
https://doaj.org/article/05e20738f4d042339e253f15effcd2af
Publikováno v:
Earth Science, Systems and Society, Vol 3 (2023)
Externí odkaz:
https://doaj.org/article/41f19b86f2c64b78a93b219b3c8d8f8c
Publikováno v:
Current Research in Food Science, Vol 3, Iss , Pp 122-133 (2020)
We use mesoscale simulations to gain insight into the digestion of biopolymers by studying the break-up dynamics of polymer aggregates (boluses) bound by physical cross-links. We investigate aggregate evolution, establishing that the linking bead fra
Externí odkaz:
https://doaj.org/article/f9f0e4abc79840ccbfff5aa2e8a50ea3
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 1, Iss 1, Pp 3-25 (2020)
Cancer development is frequently associated with dysregulation of mRNA translation to enhance both increased global protein synthesis and translation of specific mRNAs encoding oncoproteins. Thus, targeted inhibition of mRNA translation is viewed as
Externí odkaz:
https://doaj.org/article/638dfff03cd147848590c1fed1261f46
Autor:
Daiki Matsunaga, Joshua K. Hamilton, Fanlong Meng, Nick Bukin, Elizabeth L. Martin, Feodor Y. Ogrin, Julia M. Yeomans, Ramin Golestanian
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
A challenge of magnetically-actuated devices is to obtain different behaviours from each component under the same driving field. Here the authors tune the dipolar interactions between rotors to obtain different rotational behaviours when actuated by
Externí odkaz:
https://doaj.org/article/8b55c69f05f1484a874bd541ab2727c4
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Active matter systems are made up of self-driven components which extract energy from their surroundings to generate mechanical work. Here the authors review the subfield of active nematics and provide a comparison between theoretical findings and th
Externí odkaz:
https://doaj.org/article/211dc0dddc0945ebbc2a76986ab81fd5
Autor:
Flora Ascione, Sergio Caserta, Speranza Esposito, Valeria Rachela Villella, Luigi Maiuri, Mehrana R. Nejad, Amin Doostmohammadi, Julia M. Yeomans, Stefano Guido
Publikováno v:
Ascione, F, Caserta, S, Esposito, S, Rachela, V V, Maiuri, L, Nejad, M R, Doostmohammadi, A, Yeomans, J M & Guido, S 2023, ' Collective rotational motion of freely expanding T84 epithelial cell colonies ', Journal of the Royal Society Interface, vol. 20, no. 199, 20220719 . https://doi.org/10.1098/rsif.2022.0719
Coordinated rotational motion is an intriguing, yet still elusive mode of collective cell migration, which is relevant in pathological and morphogenetic processes. Most of the studies on this topic have been carried out on epithelial cells plated on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c62418fb0cebc49edd0131c002cc5d5
https://doi.org/10.1098/rsif.2022.0719
https://doi.org/10.1098/rsif.2022.0719
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Bacteria continuously inject energy into their surroundings and thus induce chaotic like flows, namely meso-scale turbulence. Here, the authors show that transition to meso-scale turbulence and inertial turbulence observed in pipes share the same sca
Externí odkaz:
https://doaj.org/article/d8fbfaaa2e7a434e90974ec394b2128b
Autor:
Jonathan H. Schatz, Eli Chapman, Abimael D. Rodríguez, Graham Packham, Cyril H. Benes, Francisco Vega, Patricia Greninger, Gillian Paine-Murrieta, Andrew J. Ambrose, Christopher J. Zerio, Praechompoo Pongtornpipat, Amit D. Amin, Lingxiao Li, Luis A. Amador, Carlos Jiménez-Romero, Elizabeth Lemm, Sarah Wilmore, Alison M. Yeomans, Joseph Tillotson, Tara L. Peters
Figure S1. Elatol was submitted to a 96-member kinome screen to evaluate specificity. Figure S2. A) Michaelis-Menten curves of eIF4A1 wild type (blue), K82R (red), and K238E (green). Michaelis- Menten constants for eIF4A1 wild type and mutants in tab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b0c08aa1ad75e37b8b895a22244a71
https://doi.org/10.1158/1078-0432.22469778.v1
https://doi.org/10.1158/1078-0432.22469778.v1
Autor:
Jonathan H. Schatz, Eli Chapman, Abimael D. Rodríguez, Graham Packham, Cyril H. Benes, Francisco Vega, Patricia Greninger, Gillian Paine-Murrieta, Andrew J. Ambrose, Christopher J. Zerio, Praechompoo Pongtornpipat, Amit D. Amin, Lingxiao Li, Luis A. Amador, Carlos Jiménez-Romero, Elizabeth Lemm, Sarah Wilmore, Alison M. Yeomans, Joseph Tillotson, Tara L. Peters
Purpose: The DEAD-box RNA helicase eIF4A1 carries out the key enzymatic step of cap-dependent translation initiation and is a well-established target for cancer therapy, but no drug against it has entered evaluation in patients. We identified and cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0a4100a7388fdcb4d088138f676666
https://doi.org/10.1158/1078-0432.c.6527340
https://doi.org/10.1158/1078-0432.c.6527340