Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M. Y. L. De Wit"'
Publikováno v:
Journal of clinical microbiology, 31(11), 2947-2951. American Society for Microbiology
In order to better understand the role of Mycobacterium leprae nasal carriage in the maintenance of infection reservoirs and transmission of leprosy, we applied a polymerase chain reaction (PCR) that detected a 531-bp fragment of the pra gene of M. l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265506b2521a2f58e1e871181969d2d1
https://doi.org/10.1128/jcm.31.11.2947-2951.1993
https://doi.org/10.1128/jcm.31.11.2947-2951.1993
Publikováno v:
Journal of clinical microbiology, 31(3), 502-506. American Society for Microbiology
The polymerase chain reaction based on the selective amplification of a 531-bp fragment of the gene encoding the proline-rich antigen of Mycobacterium leprae was applied to nasal swab specimens from leprosy patients, occupational contacts, and endemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f668d0af4513d8da124db1ffefb5d29d
https://doi.org/10.1128/jcm.31.3.502-506.1993
https://doi.org/10.1128/jcm.31.3.502-506.1993
Application of a polymerase chain reaction for the detection of Mycobacterium leprae in skin tissues
Autor:
W R Faber, M. Y. L. De Wit, N Montreewasuwat, J M Ponnighaus, S R Krieg, S R Pattyn, Rudy A. Hartskeerl, J. T. Douglas, Rabia Hussain, S B Lucas
Publikováno v:
Journal of Clinical Microbiology. 29:906-910
The polymerase chain reaction (PCR) based on the selective amplification of a 530-bp fragment of the gene encoding the proline-rich antigen of Mycobacterium leprae was applied on sections of fixed or frozen biopsy samples from leprosy patients. A sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a62fe8d14ccdd55bb2f935246c68bb1
https://doi.org/10.1128/jcm.29.5.906-910.1991
https://doi.org/10.1128/jcm.29.5.906-910.1991
Publikováno v:
Infection and Immunity. 59:433-436
Using synthetic peptides representing overlapping sequences of the 100-amino-acid-long N-terminal region of the proline-rich antigen of Mycobacterium leprae (PRA), we have mapped the epitopes in the primary structure of PRA recognized by four monoclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9c2a3bcb124add614a00f0632497ac
https://doi.org/10.1128/iai.59.1.433-436.1991
https://doi.org/10.1128/iai.59.1.433-436.1991
Publikováno v:
Infection and Immunity. 58:2821-2827
A Mycobacterium leprae expression library was constructed in the vectors EX1, pEX2, and pEX3 and screened with a pool of 19 well-absorbed sera from household contacts of leprosy patients. Twelve selected recombinants that were further characterized d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23c921a4e5e4d45764946342c97dbde
https://doi.org/10.1128/iai.58.9.2821-2827.1990
https://doi.org/10.1128/iai.58.9.2821-2827.1990
Autor:
J. E. R. Thole, M. Y. L. De Wit, Arend H. J. Kolk, L. F. E. Stabel, Paul R. Klatser, Rudy A. Hartskeerl, M E Suykerbuyk
Publikováno v:
Infection and Immunity. 58:80-87
The 36,000-molecular-weight antigen (36K antigen) of Mycobacterium leprae is a major immunogenic protein carrying common and specific antigenic determinants recognized by antibodies and T cells in leprosy patients. Recombinant DNA clones containing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068be21bc4a16232ca7ec6fd3aaab0d7
https://doi.org/10.1128/iai.58.1.80-87.1990
https://doi.org/10.1128/iai.58.1.80-87.1990
Autor:
I. A. Cree, A. Fernando, J. R. Rao, P. Ramaprasad, M. Y. L. De Wit, Paul R. Klatser, S. Madhale, W. C. S. Smith, P. D. Samson, V. K. Edward
Publikováno v:
Leprosy review, 68(4), 301-315. British Leprosy Relief Association
Recent advances in treatment have achieved a large drop in the prevalence of active leprosy cases, but the incidence is at best decreasing slowly. Most people within leprosy-endemic populations have been exposed to Mycobacterium leprae, but few devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bad0b04584f9045657160a92eca218a
https://doi.org/10.5935/0305-7518.19970038
https://doi.org/10.5935/0305-7518.19970038
Autor:
Paul R. Klatser, M. Y. L. De Wit
Publikováno v:
Microbiology (Reading, England), 140(8), 1983-1987. Society for General Microbiology
To test for genotypic variations between different isolates of Mycobacterium leprae, the causative agent of leprosy, the 282 bp spacer region between the 16S and 23S rRNA genes was amplified using PCR, and submitted to single-strand conformation poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d9a89e0cd0f8d8a4373622ca3aca5a
https://pubmed.ncbi.nlm.nih.gov/7522845
https://pubmed.ncbi.nlm.nih.gov/7522845
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 82:216-220
Two ELISA tests for detecting chloroquine in urine have been developed using polyclonal and monoclonal antibodies which react with the 7-chloro-4-aminoquinoline part of the chloroquine molecule and thus recognize chloroquine, its metabolites, and amo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d70c8d7e1ba8b8e2a21c3e9081b000
https://doi.org/10.1016/0035-9203(88)90415-4
https://doi.org/10.1016/0035-9203(88)90415-4
Publikováno v:
Microbiology. 135:2357-2364
SUMMARY: A polymerase chain reaction (PCR) using heat-stable Taq polymerase is described for the specific detection of Mycobacterium leprae, the causative agent of leprosy. A set of primers was selected on the basis of the nucleotide sequence of a ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c96eb821db63ba562730ecb827d699
https://doi.org/10.1099/00221287-135-9-2357
https://doi.org/10.1099/00221287-135-9-2357