Zobrazeno 1 - 10
of 1 451
pro vyhledávání: '"M. Weyand"'
Autor:
Kenneth J Warrington, Tanaz A Kermani, Mohanad M Elfishawi, Mahmut S Kaymakci, Sara J Achenbach, Cynthia S Crowson, Cornelia M Weyand, Matthew J Koster
Publikováno v:
RMD Open, Vol 10, Iss 1 (2024)
Objective To evaluate the incidence and outcomes of large artery (LA) involvement among patients with giant cell arteritis (GCA) and to compare LA involvement to non-GCA patients.Methods The study included Olmsted County, Minnesota, USA residents wit
Externí odkaz:
https://doaj.org/article/b6eaaff5286e43538aef9073e39c0b29
Autor:
Kevin Y. Cunningham, Benjamin Hur, Vinod K. Gupta, Courtney A. Arment, Kerry A. Wright, Thomas G. Mason, Lynne S. Peterson, Delamo I. Bekele, Daniel E. Schaffer, Marissa L. Bailey, Kara E. Delger, Cynthia S. Crowson, Elena Myasoedova, Hu Zeng, Moses Rodriguez, Cornelia M. Weyand, John M. Davis, Jaeyun Sung
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Patients with rheumatoid arthritis (RA) can test either positive or negative for circulating anti-citrullinated protein antibodies (ACPA) and are thereby categorized as ACPA-positive (ACPA+) or ACPA-negative (ACPA−), respectively. In this
Externí odkaz:
https://doaj.org/article/559a2a3dbb32484db8aed8388eb26580
Autor:
Simon Parreau, Elsa Molina, Stéphanie Dumonteil, Radjiv Goulabchand, Thomas Naves, Melanie C. Bois, Hussein Akil, Faraj Terro, Anne-Laure Fauchais, Eric Liozon, Marie-Odile Jauberteau, Cornelia M. Weyand, Kim-Heang Ly
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveTo identify the key coding genes underlying the biomarkers and pathways associated with giant cell arteritis (GCA), we performed an in situ spatial profiling of molecules involved in the temporal arteries of GCA patients and controls. Furthe
Externí odkaz:
https://doaj.org/article/b93d1be933274ba393f745b1a31e83fa
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immune memory is a requisite and remarkable property of the immune system and is the biological foundation of the success of vaccinations in reducing morbidity from infectious diseases. Some vaccines and infections induce long-lasting protection, but
Externí odkaz:
https://doaj.org/article/5f8e44d3ffef48eabe0db9641ae1be85
Autor:
Wenqiang Cao, Ines Sturmlechner, Huimin Zhang, Jun Jin, Bin Hu, Rohit R. Jadhav, Fengqin Fang, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112195- (2023)
Summary: Naive CD4+ T cells are more resistant to age-related loss than naive CD8+ T cells, suggesting mechanisms that preferentially protect naive CD4+ T cells during aging. Here, we show that TRIB2 is more abundant in naive CD4+ than CD8+ T cells a
Externí odkaz:
https://doaj.org/article/ecfd1197fa604b269269d40f24f8721e
Autor:
Simon Lambert, Wenqiang Cao, Huimin Zhang, Alex Colville, Jie-Yu Liu, Cornelia M. Weyand, Jorg J. Goronzy, Claire E. Gustafson
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
A breakdown in cellular homeostasis is thought to drive naïve T cell aging, however the link between naïve T cell homeostasis and aging in humans is poorly understood. To better address this, we developed a lymphoid organoid system that maintains r
Externí odkaz:
https://doaj.org/article/f3199be1e3fa4f94bf796c88b8c360ea
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-9 (2021)
Abstract MicroRNAs (miRNAs) are regulatory noncoding RNAs important for many aspects of cellular processes including cell differentiation and proliferation. Functions of numerous miRNAs have been identified in T cells, with miR-181a regulating T cell
Externí odkaz:
https://doaj.org/article/dd787b5dcc1347109dff3106b848ff2f
Autor:
Fengqin Fang, Wenqiang Cao, Yunmei Mu, Hirohisa Okuyama, Lingjie Li, Jingtao Qiu, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
The ectonucleotidase CD39 functions as a checkpoint in purinergic signaling on effector T cells. By depleting eATP and initiating the generation of adenosine, it impairs memory cell development and contributes to T cell exhaustion, thereby causing de
Externí odkaz:
https://doaj.org/article/9d5e1c41942241ca89dad326c17def65
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
The aging process causes profound restructuring of the host immune system, typically associated with declining host protection against cancer and infection. In the case of T cells, aging leads to the accumulation of a diverse set of T-cell aging-asso
Externí odkaz:
https://doaj.org/article/c0bb700cd76143ae97ca8fdf266102a9
Autor:
Bin Hu, Rohit R. Jadhav, Claire E. Gustafson, Sabine Le Saux, Zhongde Ye, Xuanying Li, Lu Tian, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/1ffebb6d2fb24fafa2db95ebc9619d17