Zobrazeno 1 - 10
of 174
pro vyhledávání: '"M. Werman"'
Akademický článek
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Publikováno v:
RSC Chem Biol
Whole cell-based phenotypic screens have become the primary mode of hit generation in tuberculosis (TB) drug discovery during the last two decades. Different drug screening models have been developed to mirror the complexity of TB disease in the labo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a7fe10dad63ef7e4cf3e842d51ff74
https://doi.org/10.1039/d0cb00226g
https://doi.org/10.1039/d0cb00226g
Autor:
Nicole S. Sampson, Rui Lu, Joshua M. Werman, Tianao Yuan, Natasha M. Nesbitt, Amber C. Bonds, Miguel Garcia-Diaz, Jungwon Jang
Publikováno v:
ACS Infectious Diseases. 6:2214-2224
Cholesterol is a major carbon source for Mycobacterium tuberculosis (Mtb) during infection, and cholesterol utilization plays a significant role in persistence and virulence within host macrophages. Elucidating the mechanism by which cholesterol is d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0df48c12d219c125ac94c350e63ecab
https://doi.org/10.1021/acsinfecdis.0c00329
https://doi.org/10.1021/acsinfecdis.0c00329
Autor:
Tianao, Yuan, Joshua M, Werman, Xingyu, Yin, Meng, Yang, Miguel, Garcia-Diaz, Nicole S, Sampson
Publikováno v:
ACS Infectious Diseases
The unique ability of Mycobacterium tuberculosis (Mtb) to utilize host lipids such as cholesterol for survival, persistence, and virulence has made the metabolic pathway of cholesterol an area of great interest for therapeutics development. Herein, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b42e8425339854084f0330753f81df93
https://pubmed.ncbi.nlm.nih.gov/33826843
https://pubmed.ncbi.nlm.nih.gov/33826843
Autor:
Amber C, Bonds, Tianao, Yuan, Joshua M, Werman, Jungwon, Jang, Rui, Lu, Natasha M, Nesbitt, Miguel, Garcia-Diaz, Nicole S, Sampson
Publikováno v:
ACS Infect Dis
Cholesterol is a major carbon source for Mycobacterium tuberculosis (Mtb) during infection, and cholesterol utilization plays a significant role in persistence and virulence within host macrophages. Elucidating the mechanism by which cholesterol is d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7e6c0369fede26c6666c443ff0cac83
https://pubmed.ncbi.nlm.nih.gov/32649175
https://pubmed.ncbi.nlm.nih.gov/32649175
Akademický článek
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Akademický článek
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Publikováno v:
Medical Image Analysis. 15:125-132
We present a new non-uniform sampling method for the accurate estimation of mutual information in multi-modal brain image rigid registration. Most existing density estimators used for mutual information computation incorrectly assume that the intensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a30b64160497fb47f655f2550e2d71e
https://doi.org/10.1016/j.media.2010.08.004
https://doi.org/10.1016/j.media.2010.08.004
Publikováno v:
ICIP
We describe a statistical approach to the problem of estimating the times of cell-division cycles in time-lapse movies of early mouse embryos. Our method is based on the likelihoods for cells of certain radii ranges to be in each frame — without ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::665d190c67827ae293a92b5eaf30a046
https://doi.org/10.1109/icip.2014.7025735
https://doi.org/10.1109/icip.2014.7025735
Publikováno v:
ICIP
We present an ellipse finding and fitting algorithm that uses points and tangents, rather than just points, as the basic unit of information. These units are analyzed in a hierarchy: points with tangents are paired into triangles in the first layer a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::613b0bc6ae3bd80d409c46fd7cbe3399
https://doi.org/10.1109/icip.2014.7025736
https://doi.org/10.1109/icip.2014.7025736