Zobrazeno 1 - 10
of 30
pro vyhledávání: '"M. Weipert"'
Autor:
Afsaneh Barzi, Caroline M. Weipert, Carin R. Espenschied, Victoria M. Raymond, Andrea Wang-Gillam, Mohammad Amin Nezami, Eva J. Gordon, Daruka Mahadevan, Kabir Mody
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeDespite accumulating data regarding the genomic landscape of pancreatic ductal adenocarcinoma (PDAC), olaparib is the only biomarker-driven FDA-approved targeted therapy with a PDAC-specific approval. Treating ERBB2(HER2)-amplified PDAC with a
Externí odkaz:
https://doaj.org/article/e7677069cab2423eb1241b17d63bdd06
Autor:
Michael W. Drazer, Sabah Kadri, Madina Sukhanova, Sushant A. Patil, Allison H. West, Simone Feurstein, Dalein A. Calderon, Matthew F. Jones, Caroline M. Weipert, Christopher K. Daugherty, Adrián A. Ceballos-López, Gordana Raca, Mark W. Lingen, Zejuan Li, Jeremy P. Segal, Jane E. Churpek, Lucy A. Godley
Publikováno v:
Blood Advances, Vol 2, Iss 2, Pp 146-150 (2018)
Abstract: Next-generation sequencing (NGS)–based targeted gene capture panels are used to profile hematopoietic malignancies to guide prognostication and treatment decisions. Because these panels include genes associated with hereditary hematopoiet
Externí odkaz:
https://doaj.org/article/9d39cfe2ed3a40e9bed4f702d8809afc
Publikováno v:
Journal of Adolescent and Young Adult Oncology. 10:336-341
We present the first analysis examining molecular alterations detected utilizing a clinically available cell-free circulating tumor DNA (cfDNA) assay in a cohort of patients with advanced colorectal cancer (aCRC) diagnosed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d50376b057f52ec6d8f943288083bb
https://doi.org/10.1089/jayao.2020.0080
https://doi.org/10.1089/jayao.2020.0080
Autor:
Joseph W Franses, Mir Lim, Adam M Burgoyne, Kabir Mody, Jochen Lennerz, Jeremy Chang, Robin Imperial, Stacey N Dybel, Thi M Dinh, Jude Masannat, Caroline M Weipert, David Hsiehchen
Publikováno v:
The oncologist. 27(11)
Advanced hepatocellular carcinoma (HCC) is responsive to immune checkpoint inhibitors, but there are currently no known biomarkers to predict treatment benefit. Blood TMB (bTMB) estimation via circulating tumor DNA (ctDNA) profiling can provide a con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b88ea65a69758d1f7f2698603e58960
https://pubmed.ncbi.nlm.nih.gov/36103364
https://pubmed.ncbi.nlm.nih.gov/36103364
Autor:
Jamie O. Brett, Caroline M. Weipert, Lauren L. Ritterhouse, Nicole Zhang, Junhua Yu, Lianne Y. Ryan, Laura M. Spring, Miguel N. Rivera, Jochen K. Lennerz, Dora Dias-Santagata, Leif W. Ellisen, Aditya Bardia, Seth A. Wander
Publikováno v:
Cancer Research. 82:5248-5248
Background For HR+ MBC, ESR1 point mutations (ESR1-MUT) are a common mechanism of acquired resistance to aromatase inhibition (AI); ESR1 fusions (ESR1-FUS) are rare and promote intrinsic resistance to ER-targeting drugs. Retrospective analyses of CDK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea171e854f4aab5a34646f96afff3447
https://doi.org/10.1158/1538-7445.am2022-5248
https://doi.org/10.1158/1538-7445.am2022-5248
Autor:
Jason K. Sicklick, Shumei Kato, Ryosuke Okamura, Sophia Gumas, Razelle Kurzrock, Suzanna Lee, Caroline M. Weipert, Jennifer Saam
Publikováno v:
JCO Precision Oncology
PURPOSE Cancer of unknown primary (CUP) is a metastatic disease with unidentifiable primary tumor. Somatic alterations can be assessed noninvasively via liquid biopsies interrogating cell-free DNA (cfDNA). METHODS We evaluated 1,931 patients with CUP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f130308aa4d99f28a5911a29601c514
https://pubmed.ncbi.nlm.nih.gov/34778692
https://pubmed.ncbi.nlm.nih.gov/34778692
Autor:
K Kulkarni, A. R. Bradbury, D Schacht, O. I. Olopade, Akila Raoul, Marion S. Verp, Sarah M. Nielsen, Andrea Amico, Hiroyuki Abe, Iris L. Romero, R Fang, Kristen Wroblewski, Linda Patrick-Miller, Deepa Sheth, Fay J. Hlubocky, Caroline M. Weipert
Publikováno v:
Cancer Research. 78:P5-19
Purpose: To evaluate the psychosocial impact of semi-annual dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) screening in women at high-risk for breast cancer. Background: For women with BRCA1 and BRCA2 mutations and/or a personal or fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ed436b521e59dc7d7bc3ab7afc438d6
https://doi.org/10.1158/1538-7445.sabcs17-p5-19-04
https://doi.org/10.1158/1538-7445.sabcs17-p5-19-04
Autor:
Olufunmilayo I. Olopade, Sonia S. Kupfer, Matthew F. Jones, Caroline M. Weipert, Allison H. West, Jessica Stoll, Sarah M. Nielsen, Kathleen R. Blazer, Jeffrey N. Weitzel
Publikováno v:
Familial Cancer. 17:495-505
Comprehensive genomic cancer risk assessment (GCRA) helps patients, family members, and providers make informed choices about cancer screening, surgical and chemotherapeutic risk reduction, and genetically targeted cancer therapies. The increasing av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ee012f73b84573407c31c2d894fc50
https://doi.org/10.1007/s10689-018-0070-x
https://doi.org/10.1007/s10689-018-0070-x
Autor:
Jeremy P. Segal, Allison H. West, Jane E. Churpek, Sabah Kadri, Lucy A. Godley, Michael W. Drazer, Sushant A. Patil, Madina Sukhanova, Zejuan Li, Simone Feurstein, Gordana Raca, Matthew F. Jones, Caroline M. Weipert, Mark W. Lingen, Dalein A. Calderon, Adrián A. Ceballos-López, Christopher K. Daugherty
Publikováno v:
Blood Advances. 2:146-150
Next-generation sequencing (NGS)–based targeted gene capture panels are used to profile hematopoietic malignancies to guide prognostication and treatment decisions. Because these panels include genes associated with hereditary hematopoietic maligna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aadb83005855db40629b199f81bedc0
https://doi.org/10.1182/bloodadvances.2017013037
https://doi.org/10.1182/bloodadvances.2017013037
Autor:
Beverly M. Yashar, Arul M. Chinnaiyan, Jessica Everett, Brian J. Zikmund-Fisher, Victoria M. Raymond, Raymond De Vries, Caroline M. Weipert, J. Scott Roberts, Kerry A. Ryan
Publikováno v:
Journal of Genetic Counseling. 27:187-196
The amount of information produced by genomic sequencing is vast, technically complicated, and can be difficult to interpret. Appropriately tailoring genomic information for non-geneticists is an essential next step in the clinical use of genomic seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5477abc010251390df74b1c51e24cdf9
https://doi.org/10.1007/s10897-017-0134-3
https://doi.org/10.1007/s10897-017-0134-3