Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials

Autor: Cathrine Axfors, Andreas M. Schmitt, Perrine Janiaud, Janneke van’t Hooft, Sherief Abd-Elsalam, Ehab F. Abdo, Benjamin S. Abella, Javed Akram, Ravi K. Amaravadi, Derek C. Angus, Yaseen M. Arabi, Shehnoor Azhar, Lindsey R. Baden, Arthur W. Baker, Leila Belkhir, Thomas Benfield, Marvin A. H. Berrevoets, Cheng-Pin Chen, Tsung-Chia Chen, Shu-Hsing Cheng, Chien-Yu Cheng, Wei-Sheng Chung, Yehuda Z. Cohen, Lisa N. Cowan, Olav Dalgard, Fernando F. de Almeida e Val, Marcus V. G. de Lacerda, Gisely C. de Melo, Lennie Derde, Vincent Dubee, Anissa Elfakir, Anthony C. Gordon, Carmen M. Hernandez-Cardenas, Thomas Hills, Andy I. M. Hoepelman, Yi-Wen Huang, Bruno Igau, Ronghua Jin, Felipe Jurado-Camacho, Khalid S. Khan, Peter G. Kremsner, Benno Kreuels, Cheng-Yu Kuo, Thuy Le, Yi-Chun Lin, Wu-Pu Lin, Tse-Hung Lin, Magnus Nakrem Lyngbakken, Colin McArthur, Bryan J. McVerry, Patricia Meza-Meneses, Wuelton M. Monteiro, Susan C. Morpeth, Ahmad Mourad, Mark J. Mulligan, Srinivas Murthy, Susanna Naggie, Shanti Narayanasamy, Alistair Nichol, Lewis A. Novack, Sean M. O’Brien, Nwora Lance Okeke, Léna Perez, Rogelio Perez-Padilla, Laurent Perrin, Arantxa Remigio-Luna, Norma E. Rivera-Martinez, Frank W. Rockhold, Sebastian Rodriguez-Llamazares, Robert Rolfe, Rossana Rosa, Helge Røsjø, Vanderson S. Sampaio, Todd B. Seto, Muhammad Shahzad, Shaimaa Soliman, Jason E. Stout, Ireri Thirion-Romero, Andrea B. Troxel, Ting-Yu Tseng, Nicholas A. Turner, Robert J. Ulrich, Stephen R. Walsh, Steve A. Webb, Jesper M. Weehuizen, Maria Velinova, Hon-Lai Wong, Rebekah Wrenn, Fernando G. Zampieri, Wu Zhong, David Moher, Steven N. Goodman, John P. A. Ioannidis, Lars G. Hemkens

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

Abstract Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate the effects of hydro

Externí odkaz: https://doaj.org/article/d742d7263e7f4393b9fbfd3d3114ad61

Bacillus Calmette-Guérin vaccine to reduce COVID-19 infections and hospitalisations in healthcare workers - a living systematic review and prospective ALL-IN meta-analysis of individual participant data from randomised controlled trials

Autor: J.A. (Judith) ter Schure, Alexander Ly, Lisa Belin, Christine S. Benn, Marc J.M. Bonten, Jeffrey D. Cirillo, Johanna A.A. Damen, Inês Fronteira, Kelly D. Hendriks, Ana Paula Junqueira-Kipnis, André Kipnis, Odile Launay, Jose Euberto Mendez-Reyes, Judit Moldvay, Mihai G. Netea, Sebastian Nielsen, Caryn M. Upton, Gerben van den Hoogen, Jesper M. Weehuizen, Peter D. Grünwald, C.H. (Henri) van Werkhoven

BACKGROUNDThe objective is to determine the impact of the Bacillus Calmette-Guérin (BCG) vaccine compared to placebo or no vaccine on COVID-19 infections and hospitalisations in healthcare workers. We are using a living and prospective approach to I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee9464f10d29f66e0a65594b8199056
https://doi.org/10.1101/2022.12.15.22283474

No increased risk of mature B-cell non-Hodgkin lymphoma after Q fever detected: results from a 16-year ecological analysis of the Dutch population incorporating the 2007-2010 Q fever outbreak

Autor: Jesper M Weehuizen, Sonja E van Roeden, Sander J Hogewoning, Wim van der Hoek, Marc J M Bonten, Andy I M Hoepelman, Chantal P Bleeker-Rovers, Peter C Wever, Jan Jelrik Oosterheert

Publikováno v: International Journal of Epidemiology, 51, 1481-1488
International Journal of Epidemiology, 51, 5, pp. 1481-1488

Background A causative role of Coxiella burnetii (the causative agent of Q fever) in the pathogenesis of B-cell non-Hodgkin lymphoma (NHL) has been suggested, although supporting studies show conflicting evidence. We assessed whether this association

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d50f73585ed730dcf51f6b33e694f5d
http://hdl.handle.net/2066/286857

Fluorescence in situ hybridization for detecting Coxiella burnetii in tissue samples from chronic Q fever patients

Autor: Sheila B. Buijs, Jesper M. Weehuizen, Tim K. Jensen, Mette Boye, Mirjam HA. Hermans, Peet TGA. Nooijen, Andy IM. Hoepelman, Chantal P. Bleeker-Rovers, Jan Jelrik Oosterheert, Peter C. Wever

Publikováno v: Clinical Microbiology and Infection, 28, 1502.e1-1502.e5
Buijs, S B, Weehuizen, J M, Jensen, T K, Boye, M, Hermans, M HA, Nooijen, P TGA, Hoepelman, A IM, Bleeker-Rovers, C P, Oosterheert, J J & Wever, P C 2022, ' Fluorescence in situ hybridization for detecting Coxiella burnetii in tissue samples from chronic Q fever patients ', Clinical Microbiology and Infection, vol. 28, no. 11, pp. 1502.e1-1502.e5 . https://doi.org/10.1016/j.cmi.2022.06.015
Clinical Microbiology and Infection, 28, 11, pp. 1502.e1-1502.e5

Objective: Detection of the intracellular bacterium Coxiella burnetii, causative agent of chronic Q fever, is notoriously difficult. Diagnosis of and duration of antibiotic treatment for chronic Q fever is partly determined by detection of the bacter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b5be639170931737511c96a5b76352
https://doi.org/10.1016/j.cmi.2022.06.015

Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials

Autor: Steven N. Goodman, Norma E. Rivera-Martinez, Magnus Nakrem Lyngbakken, David Moher, John P. A. Ioannidis, Frank W. Rockhold, Todd B. Seto, Helge Røsjø, Vincent Dubée, Ahmad Mourad, Andrea B. Troxel, Carmen M. Hernández-Cárdenas, Vanderson de Souza Sampaio, Thuy Le, Andy I. M. Hoepelman, Fernando Val, Sean M. O'Brien, Ting Yu Tseng, Leila Belkhir, Susanna Naggie, Patricia Meza-Meneses, Marvin A.H. Berrevoets, Javed Akram, Alistair Nichol, Léna Perez, Rebekah Wrenn, Susan C. Morpeth, Laurent Perrin, Felipe Jurado-Camacho, Lindsey R. Baden, Shehnoor Azhar, Bryan J. McVerry, Cheng-Yu Kuo, Arantxa Remigio-Luna, Thomas Hills, Cathrine Axfors, Ireri Thirion-Romero, Steve Webb, Wuelton Marcelo Monteiro, Jason E. Stout, Jesper M. Weehuizen, Peter G. Kremsner, Shanti Narayanasamy, Derek C. Angus, Yehuda Z. Cohen, Shu Hsing Cheng, Gisely Cardoso de Melo, Rossana Rosa, Nwora Lance Okeke, Stephen R. Walsh, Srinivas Murthy, Anissa Elfakir, Mark J. Mulligan, Olav Dalgard, Cheng-Pin Chen, Tse Hung Lin, Fernando G. Zampieri, Khalid S. Khan, Yi-Wen Huang, Anthony C. Gordon, Yaseen M. Arabi, Wu Zhong, Hon Lai Wong, Wei Sheng Chung, Bruno Igau, Andreas M. Schmitt, Maria Velinova, Robert J. Ulrich, Nicholas A Turner, Wu Pu Lin, Janneke van’t Hooft, Shaimaa Soliman, Lennie P. G. Derde, Colin McArthur, Arthur W. Baker, Benno Kreuels, Ravi K. Amaravadi, Ronghua Jin, Benjamin S. Abella, Sherief Abd-Elsalam, Thomas Benfield, Lewis A. Novack, Lars G. Hemkens, Ehab F. Abdo, Perrine Janiaud, Sebastian Rodriguez-Llamazares, Chien Yu Cheng, Muhammad Shahzad, Robert Rolfe, Tsung Chia Chen, Yi-Chun Lin, Rogelio Perez-Padilla, Marcus V. G. Lacerda, Lisa N. Cowan

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-2 (2021)
Nature Communications

Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate the effects of hydroxychloroq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd12e44c7dfe0fbf267480cac84e1c96
http://hdl.handle.net/10044/1/89425