Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M. W. Quick"'
Autor:
M. W. Quick, William Marszalec, Robin A. J. Lester, Gary L. Aistrup, Toshio Narahashi, D. B. Sattelle, C. P. Fenster, Billy R. Martin, Edward D. Levin
Publikováno v:
Toxicological Sciences. 57:193-202
Nicotine has long been known to interact with nicotinic acetylcholine (ACh) receptors since Langley used it extensively to chart sympathetic ganglia a century ago. It has also been used as an effective insecticide. However, it was not until the 1990s
Autor:
M W, Quick
Publikováno v:
Handbook of experimental pharmacology. (175)
The SNARE hypothesis of vesicle fusion proposes that a series of protein-protein interactions governs the delivery of vesicles to various membrane targets such as the Golgi network and the plasma membrane. Key players in this process include members
Autor:
T L, Whitworth, M W, Quick
Publikováno v:
Biochemical Society transactions. 29(Pt 6)
Pregabalin [(S)-(+)-3-isobutylgaba] and gabapentin [1-(aminomethyl)cyclohexane acetic acid] are gamma-aminobutyric acid (GABA) derivatives that are effective in the treatment of behavioural disorders, convulsions, epilepsy and hyperalgesia. The mecha
Autor:
N, Horton, M W, Quick
Publikováno v:
Molecular membrane biology. 18(1)
Neurotransmitter transporters are regulated through a variety of signal transduction mechanisms which appear to operate in order to maintain appropriate levels of transmitter in the synaptic cleft. One such mechanism is the trafficking of the transpo
Autor:
C P, Fenster, M L, Beckman, J C, Parker, E B, Sheffield, T L, Whitworth, M W, Quick, R A, Lester
Publikováno v:
Molecular pharmacology. 55(3)
Neuronal nicotinic acetylcholine receptor (nAChR) desensitization is hypothesized to be a trigger for long-term changes in receptor number and function observed after chronic administration of nicotine at levels similar to those found in persons who
Publikováno v:
The Journal of General Physiology
We constructed chimeras of the rat beta 2 and beta 4 neuronal nicotinic subunits to locate the regions that contribute to differences between the acetylcholine (ACh) dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 receptors. Expr
Publikováno v:
Investigative ophthalmologyvisual science. 35(12)
To examine accommodation and accommodative convergence relationships in naturally strabismic monkeys.Photorefraction was used to measure accommodative responses of each eye under monocular and binocular viewing conditions. These accommodative results
Publikováno v:
The Journal of biological chemistry. 269(20)
We report that activators and inhibitors of protein kinase C (PKC) and protein phosphatases regulate the activity of a cloned rat brain gamma-aminobutyric acid (GABA) transporter (GAT1) expressed in Xenopus oocytes. Four compounds known to activate P
Publikováno v:
Investigative ophthalmologyvisual science. 33(10)
A standard set of clinical prism and cover tests and a recently developed photographic method were used to assess binocular alignment in ten monkeys that previously were determined to have a naturally occurring infantile strabismus. Extensive measure
Publikováno v:
BioTechniques. 13(3)