Zobrazeno 1 - 10
of 134
pro vyhledávání: '"M. W. Quick"'
Autor:
M. W. Quick, William Marszalec, Robin A. J. Lester, Gary L. Aistrup, Toshio Narahashi, D. B. Sattelle, C. P. Fenster, Billy R. Martin, Edward D. Levin
Publikováno v:
Toxicological Sciences. 57:193-202
Nicotine has long been known to interact with nicotinic acetylcholine (ACh) receptors since Langley used it extensively to chart sympathetic ganglia a century ago. It has also been used as an effective insecticide. However, it was not until the 1990s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12646132ef9a93e41fa425f2ccf6cf6a
https://doi.org/10.1093/toxsci/57.2.193
https://doi.org/10.1093/toxsci/57.2.193
Autor:
M W, Quick
Publikováno v:
Handbook of experimental pharmacology. (175)
The SNARE hypothesis of vesicle fusion proposes that a series of protein-protein interactions governs the delivery of vesicles to various membrane targets such as the Golgi network and the plasma membrane. Key players in this process include members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a41ffad124cf4cc607d9701e56c27c1
https://pubmed.ncbi.nlm.nih.gov/16722236
https://pubmed.ncbi.nlm.nih.gov/16722236
Autor:
T L, Whitworth, M W, Quick
Publikováno v:
Biochemical Society transactions. 29(Pt 6)
Pregabalin [(S)-(+)-3-isobutylgaba] and gabapentin [1-(aminomethyl)cyclohexane acetic acid] are gamma-aminobutyric acid (GABA) derivatives that are effective in the treatment of behavioural disorders, convulsions, epilepsy and hyperalgesia. The mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f412cac05ff948f0967c35a2ec99580e
https://pubmed.ncbi.nlm.nih.gov/11709066
https://pubmed.ncbi.nlm.nih.gov/11709066
Autor:
N, Horton, M W, Quick
Publikováno v:
Molecular membrane biology. 18(1)
Neurotransmitter transporters are regulated through a variety of signal transduction mechanisms which appear to operate in order to maintain appropriate levels of transmitter in the synaptic cleft. One such mechanism is the trafficking of the transpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a85197da20de08f6f8ada19b5aaf4ce5
https://pubmed.ncbi.nlm.nih.gov/11396610
https://pubmed.ncbi.nlm.nih.gov/11396610
Autor:
C P, Fenster, M L, Beckman, J C, Parker, E B, Sheffield, T L, Whitworth, M W, Quick, R A, Lester
Publikováno v:
Molecular pharmacology. 55(3)
Neuronal nicotinic acetylcholine receptor (nAChR) desensitization is hypothesized to be a trigger for long-term changes in receptor number and function observed after chronic administration of nicotine at levels similar to those found in persons who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be3d21f954ac8df3e521111fbebcac7d
https://pubmed.ncbi.nlm.nih.gov/10051526
https://pubmed.ncbi.nlm.nih.gov/10051526
Publikováno v:
The Journal of General Physiology
We constructed chimeras of the rat beta 2 and beta 4 neuronal nicotinic subunits to locate the regions that contribute to differences between the acetylcholine (ACh) dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 receptors. Expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238d7d562517492ce4592b0b406880dd
https://pubmed.ncbi.nlm.nih.gov/7561742
https://pubmed.ncbi.nlm.nih.gov/7561742
Publikováno v:
Investigative ophthalmologyvisual science. 35(12)
To examine accommodation and accommodative convergence relationships in naturally strabismic monkeys.Photorefraction was used to measure accommodative responses of each eye under monocular and binocular viewing conditions. These accommodative results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91eac30739db00bc7103087ea7673c31
https://pubmed.ncbi.nlm.nih.gov/7960589
https://pubmed.ncbi.nlm.nih.gov/7960589
Publikováno v:
The Journal of biological chemistry. 269(20)
We report that activators and inhibitors of protein kinase C (PKC) and protein phosphatases regulate the activity of a cloned rat brain gamma-aminobutyric acid (GABA) transporter (GAT1) expressed in Xenopus oocytes. Four compounds known to activate P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bbb1369b1e3220cba9023f3607260e2
https://pubmed.ncbi.nlm.nih.gov/8182081
https://pubmed.ncbi.nlm.nih.gov/8182081
Publikováno v:
Investigative ophthalmologyvisual science. 33(10)
A standard set of clinical prism and cover tests and a recently developed photographic method were used to assess binocular alignment in ten monkeys that previously were determined to have a naturally occurring infantile strabismus. Extensive measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::003326390e9b264fd4a22fb368af146c
https://pubmed.ncbi.nlm.nih.gov/1526747
https://pubmed.ncbi.nlm.nih.gov/1526747
Publikováno v:
BioTechniques. 13(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::463aedc9da1a7f3c73fa64bd913d839e
https://pubmed.ncbi.nlm.nih.gov/1356369
https://pubmed.ncbi.nlm.nih.gov/1356369