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A cytochrome P450 was engineered to selectively incorporate Ir(Me)-deuteroporphyrin IX (Ir(Me)-DPIX), in lieu of heme, in bacterial cells. Cofactor selectivity was altered by introducing mutations within the heme-binding pocket that discriminate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9e252b0850846ddfb3874e429f749c
https://europepmc.org/articles/PMC5875912/
https://europepmc.org/articles/PMC5875912/
Autor:
Evan W. Reynolds, M. W. McHenry, F. Cannac, Eric M. Brustad, Christopher D. Snow, Joshua G. Gober
Publikováno v:
Journal of the American Chemical Society. 138:14506-14506