Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M. W. Lunnon"'
Publikováno v:
Cerebrovascular Diseases. 8:31-37
Background: 619C89 is a use-dependent sodium channel blocker which reduces hemispheric infarction volume by up to 60% after permanent middle cerebral artery occlusion in rats. Intravenous doses of up to 1 mg/kg have been well tolerated by healthy you
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b37269c967f584f098e35e24b957ad
https://doi.org/10.1159/000015812
https://doi.org/10.1159/000015812
Autor:
I. J. Fraser, Keith W. Muir, John Posner, M. W. Lunnon, S. F. Hobbiger, Z. Hussein, Kennedy R. Lees
Publikováno v:
British Journal of Clinical Pharmacology. 41:505-511
1. This was a multi-centre, placebo controlled, randomized, dose-escalating design study in which five dosing regimens of 619C89/placebo were evaluated in 48 stroke patients. Loading infusions of 0.5, 1, 1.5, 2 and 2.5 mg kg-1 over 1 h were followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5036617c89b4b675c6d6395e00b1ef38
https://doi.org/10.1046/j.1365-2125.1996.03625.x
https://doi.org/10.1046/j.1365-2125.1996.03625.x
Autor:
M. W. Lunnon, D. W. Davies, H. P. Keller, J. Erwin, N. M. G. Debbas, G.S. Butrous, A. J. Camm, Anthony W. Nathan
Publikováno v:
European heart journal. 9(5)
DPI201-106 is a new positive inotropic agent. The cardiac electrophysiology of 16 patients was studied before and during DPI 201-106 administration (loading dose of intravenous DPI 201-106, 1.8 mg kg-1 h-1 administered over 10 min, followed by a main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f836faaaa0ec7b8d782dfd210ad5506
https://pubmed.ncbi.nlm.nih.gov/3402464
https://pubmed.ncbi.nlm.nih.gov/3402464
Publikováno v:
Chemischer Informationsdienst. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32e6abf7eec3cea883963bbfe5eba8fb
https://doi.org/10.1002/chin.197804353
https://doi.org/10.1002/chin.197804353
Publikováno v:
European heart journal. 9(5)
DPI 201-106 is a novel compound unrelated to other cardioactive agents and has been shown to have an inotropic effect in animal preparations. The drug was given by intravenous infusion (20 mg over 10 min) to 10 patients with moderate cardiac failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c145afae87f026d1c6737ec6b7a13e3
https://pubmed.ncbi.nlm.nih.gov/3402465
https://pubmed.ncbi.nlm.nih.gov/3402465
Autor:
M. W. LUNNON, J. MACMILLAN
Publikováno v:
Chemischer Informationsdienst. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5348a0f661d3238a76ccfb147b57d46
https://doi.org/10.1002/chin.197804322
https://doi.org/10.1002/chin.197804322