Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M. W. Heartlein"'
Autor:
M W, Heartlein
Publikováno v:
Progress in clinical and biological research.
Chromosome instability associated with human alphoid DNA transfected into the Chinese hamster genome
Publikováno v:
Molecular and Cellular Biology. 8:3611-3618
Repetitive DNA sequences have been implicated in the mediation of DNA rearrangement in mammalian cells. We have tested this hypothesis by using a dihydrofolate reductase (DHFR) expression vector into which candidate sequences were inserted. DHFR- Chi
Autor:
David M. DeMarini, Alan J. Katz, J. C. Means, Herman E. Brockman, Michael J. Plewa, M. W. Heartlein
Publikováno v:
Environmental mutagenesis. 3(5)
We have studied the mutagenicity of the water from Lake Bloomington and of the tap water that is made from the lake water. The lake, which is the source of drinking water for Bloomington, Illinois (pop. 44,000), is surrounded by land that is farmed i
Publikováno v:
Basic life sciences.
The thymidine (dThd) analog 5-bromodeoxyuridine (BrdUrd) is widely used in studies of the induction of sister chromatid exchanges (SCEs), since growth in the presence of BrdUrd allows the subsequent differential staining of the chromosomes through th
Publikováno v:
Experimental cell research. 169(1)
Bloom's syndrome is characterized by a high sister chromatid exchange (SCE) frequency, the basis for which is not yet understood. Immunofluorescent detection of SCE formation in dermal fibroblasts was employed over a wide range of 5-bromodeoxyuridine