Zobrazeno 1 - 4 of 4 pro vyhledávání: '"M. W. Calcutt"'
1
Electrochemical Oxidation of Ochratoxin A: Correlation with 4-Chlorophenol
Autor: M W Calcutt, Ronald E. Noftle, Richard A. Manderville, Ivan G. Gillman
Publikováno v: Chemical Research in Toxicology. 14:1266-1272
Ochratoxin A (OTA, 1A) is a mycotoxin implicated in human kidney carcinogenesis, in which oxidative activation is believed to play a key role. To gain an understanding of the oxidative behavior of the toxin, we have carried out an electrochemical stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbc99602fcee58c4c26bd3353892418
https://doi.org/10.1021/tx015516q
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2
Final results of phase I and pharmacokinetic study of SJG-136 administered on a daily x 5 schedule
Autor: Wendy L. VerMeulen, D. L. Hachey, Jordan Berlin, I. Puzanov, Mace L. Rothenberg, W. Lee, M. W. Calcutt, John A. Hartley, Alice P. Chen, Victoria J. Spanswick
Publikováno v: Journal of Clinical Oncology. 27:e13506-e13506
e13506 Background: SJG-136 is a pyrrolobenzodiazepine dimer that forms covalent DNA crosslinks in a sequence-specific manner in the minor groove. In vitro testing demonstrated a broad pattern of antitumor activity in sub-nmol concentrations. A phase
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc7314814156a2532ffca2f0e1c33108
https://doi.org/10.1200/jco.2009.27.15_suppl.e13506
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