Zobrazeno 1 - 10
of 978
pro vyhledávání: '"M. Volm"'
Autor:
M Volm, Thomas Efferth
Publikováno v:
Archives of Toxicology. 91:2515-2538
The detoxification of toxic substances is of general relevance in all biological systems. The plethora of exogenous xenobiotic compounds and endogenous toxic metabolic products explains the evolutionary pressure of all organisms to develop molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c8f9a6efbc917090dd259e4979ae64
https://doi.org/10.1007/s00204-017-1938-5
https://doi.org/10.1007/s00204-017-1938-5
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 107:1683-1688
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::309bb6a753e100b9e857590f7cab2e30
https://doi.org/10.1055/s-2008-1070189
https://doi.org/10.1055/s-2008-1070189
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 116:1303-1306
The resistance of tumours against doxorubicin was determined in vitro and compared with their smoking habits in 94 patients (81 males and 13 females; mean age 59 [38-76] years) with non-small-cell lung tumour. Among non-smokers (n = 22) 11 tumours we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::559ce7fd3511e7a742b5f08d337a151f
https://doi.org/10.1055/s-2008-1063750
https://doi.org/10.1055/s-2008-1063750
Publikováno v:
British Journal of Cancer
Data obtained from multiple sources indicate that no single mechanism can explain the resistance to chemotherapy exhibited by non-small cell lung carcinomas. The multi-factorial nature of drug resistance implies that the analysis of comprising expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8233a2112975ef7d43aca7b5ab338138
https://doi.org/10.1038/sj.bjc.6600463
https://doi.org/10.1038/sj.bjc.6600463
Autor:
M Volm, Thomas Efferth
Publikováno v:
Resistance to Targeted Anti-Cancer Therapeutics ISBN: 9783319098005
Success of cancer chemotherapy is limited by simultaneous resistance towards many anticancer drugs making clinical combination therapy protocols less efficient. P-glycoprotein represents an efflux pump of the ABC transporter family, which recognizes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc557a0f78ea758e07ac525e48bc353
https://doi.org/10.1007/978-3-319-09801-2_1
https://doi.org/10.1007/978-3-319-09801-2_1
Publikováno v:
Resistance to Targeted Anti-Cancer Therapeutics ISBN: 9783319098005
Multidrug resistance of malignant tumors severely hampers their successful treatment frequently leading to fatal consequences for affected patients. During the past three decades, many efforts have been spent to develop strategies to overcome multidr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0acba23d5185a0e965cfba1b0d273191
https://doi.org/10.1007/978-3-319-09801-2_7
https://doi.org/10.1007/978-3-319-09801-2_7
Publikováno v:
Therapeutics and Clinical Risk Management
Theodor H Lippert,1 Hans-Jörg Ruoff,1 Manfred Volm2 1Medical Faculty, University of Tübingen, Tübingen, Germany; 2Medical Faculty, University of Heidelberg, Heidelberg, Germany Abstract: Clinical practice guidelines are indispensable for such a va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f068c3647c2ba233d08c8901cb1b1011
https://www.dovepress.com/could-a-revision-of-the-current-guidelines-for-cancer-drug-use-improve-peer-reviewed-article-TCRM
https://www.dovepress.com/could-a-revision-of-the-current-guidelines-for-cancer-drug-use-improve-peer-reviewed-article-TCRM
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 111:676-678
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b8c31f55b7bd608d1810ded8dc17e69
https://doi.org/10.1055/s-2008-1068512
https://doi.org/10.1055/s-2008-1068512
Publikováno v:
Carcinogenesis. 19:1247-1250
Eighty-three non-small cell lung carcinomas (NSCLC) of previously untreated patients were analysed for expression of O 6 -methylguanine-DNA methyltransferase (MGMT) by means of immunohistochemistry. Expression of MGMT was detected in 62 of 83 tumours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cd5d30e2c5b8c7bbf72b8873fc3435
https://doi.org/10.1093/carcin/19.7.1247
https://doi.org/10.1093/carcin/19.7.1247
Publikováno v:
British Journal of Cancer
Vascular endothelial growth factor (VEGF) expression, vascularisation and tumour cell proliferation were analysed in 91 human epidermoid lung carcinomas using immunohistochemistry. A polyclonal anti-VEGF antibody was used for VEGF expression, a polyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a868bcaf745274e96f45c66ad3b57223
https://doi.org/10.1038/bjc.1996.166
https://doi.org/10.1038/bjc.1996.166