Synovial fluid from end-stage osteoarthritis induces proliferation and fibrosis of articular chondrocytes via MAPK and RhoGTPase signaling

Autor: B.A.C. Housmans, M. Neefjes, D.A.M. Surtel, M. Vitík, A. Cremers, L.W. van Rhijn, P.M. van der Kraan, G.G.H. van den Akker, T.J.M. Welting

Publikováno v: Osteoarthritis and Cartilage, 30(6), 862-874. ELSEVIER SCI LTD
Osteoarthritis and Cartilage, 30, 6, pp. 862-874
Osteoarthritis and Cartilage, 30, 862-874

OBJECTIVES: Alterations in the composition of synovial fluid have been associated with adverse effects on cartilage integrity and function. Here, we examined the phenotypic and proliferative behavior of human articular chondrocytes when cultured in v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5cf5ff5494d04a2b0dab2a910faba3
https://doi.org/10.1016/j.joca.2021.12.015