Zobrazeno 1 - 10
of 2 028
pro vyhledávání: '"M. Vierling"'
Autor:
Stelian Camara Dit Pinto, Jalal Cherkaoui, Debarshi Ghosh, Valentine Cazaubon, Kenza E. Benzeroual, Steven M. Levine, Mohammed Cherkaoui, Gagan K. Sood, Sharmila Anandasabapathy, Sadhna Dhingra, John M. Vierling, Nicolas R. Gallo
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Addressing drug-induced liver injury is crucial in drug development, often causing Phase III trial failures and market withdrawals. Traditional animal models fail to predict human liver toxicity accurately. Virtual twins of human organs pres
Externí odkaz:
https://doaj.org/article/9c77922ea234497ebfb17e16f09b1216
Autor:
Jessica I. Sanchez, Antoine C. Fontillas, Suet-Ying Kwan, Caren I. Sanchez, Tiffany L. Calderone, Jana L. Lee, Ahmed Elsaiey, Darrel W. Cleere, Peng Wei, John M. Vierling, David W. Victor, Laura Beretta
Publikováno v:
JHEP Reports, Vol 6, Iss 8, Pp 101119- (2024)
Background & Aims: The effectiveness of surveillance for hepatocellular carcinoma (HCC) in patients with cirrhosis is limited, due to inadequate risk stratification and suboptimal performance of current screening modalities. Methods: We developed a m
Externí odkaz:
https://doaj.org/article/abe801a0a33d45afa78bfe1046253a94
Publikováno v:
Frontiers in Gastroenterology, Vol 3 (2024)
BackgroundWilson disease (WD) is a rare and potentially fatal genetic disorder caused by accumulation of toxic levels of copper. Current treatments include chelating agents and/or zinc. We characterized real-world US treatment patterns in patients wi
Externí odkaz:
https://doaj.org/article/9e13711345fe47a3be21442b88e9d97a
Publikováno v:
Frontiers in Gastroenterology, Vol 2 (2024)
IntroductionThere are limited data from the United States regarding the real-world signs and symptoms of Wilson disease (WD). This retrospective, observational medical chart review was conducted to identify real-world characteristics of patients with
Externí odkaz:
https://doaj.org/article/1fdf5400e80f4bf7819aa3c0c2c2cdc8
Autor:
Anjiya Shaikh, MBBS, Karthik Goli, BS, Nicole E. Rich, MD, Jihane N. Benhammou, MD, PhD, Saira Khaderi, MD, PhD, Ruben Hernaez, MD, PhD, Vatche G. Agopian, MD, John M. Vierling, MD, Donghee Kim, MD, PhD, Aijaz Ahmed, MD, John A. Goss, MD, Abbas Rana, MD, Fasiha Kanwal, MD, MSHS, George Cholankeril, MD, MSECR,
Publikováno v:
Transplantation Direct, Vol 8, Iss 5, p e1313 (2022)
Background. To reduce the disparity in access to liver transplant (LT), United Network for Organ Sharing implemented an exception policy in May 2019, which capped hepatocellular carcinoma (HCC) exception score to the median Model for End-Stage Liver
Externí odkaz:
https://doaj.org/article/80f4df0ab8ef4f348409278ef721aecc
Autor:
Erin C. Boone, Hua Xiao, Michael M. Vierling, Logan M. Decker, Victor T. Sy, Rana F. Kennedy, Marilyn A. Bonham, Shannon F. Schmitz, Annie M. John, Thomas M. Hammond, Patrick K. T. Shiu
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 1919-1927 (2020)
In the filamentous fungus Neurospora crassa, genes unpaired during meiosis are silenced by a process known as meiotic silencing by unpaired DNA (MSUD). MSUD utilizes common RNA interference (RNAi) proteins, such as Dicer and Argonaute, to target homo
Externí odkaz:
https://doaj.org/article/cf5bfeb618424387be3af2330132cf8d
Autor:
Hua Xiao, Michael M Vierling, Rana F Kennedy, Erin C Boone, Logan M Decker, Victor T Sy, Jackson B Haynes, Michelle A Williams, Patrick K T Shiu
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/6b0689c081864f9e87566bf0a6ceb52f
Autor:
Gideon M. Hirschfield, Jenny Heathcote
Publikováno v:
New England Journal of Medicine. 358:1874-1875
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a39a9e39a01fa3c8a558f18e1ac083b6
https://doi.org/10.1056/nejmbkrev59337
https://doi.org/10.1056/nejmbkrev59337
Autor:
Hua Xiao, Michael M Vierling, Rana F Kennedy, Erin C Boone, Logan M Decker, Victor T Sy, Jackson B Haynes, Michelle A Williams, Patrick K T Shiu
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 10 (2021)
AbstractIn Neurospora crassaNeurosporaCaenorhabditis elegans
Externí odkaz:
https://doaj.org/article/885eeb2fa70449e5b053394b7ce729b9
Autor:
Wayne Eskridge, John M Vierling, Wayne Gosbee, Gabriella A Wan, May-Linh Hyunh, Henry E Chang
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260320 (2021)
The screening for undiagnosed non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (SUNN) study was a population-based screening study that aimed to provide proof of concept to encourage community-level screening and detection for this
Externí odkaz:
https://doaj.org/article/6db50ebd9eee47edb077a78a6d7f5ec2