Zobrazeno 1 - 10
of 297
pro vyhledávání: '"M. Verheijen"'
Autor:
Claire S. Chung, Yi Kou, Sarah J. Shemtov, Bert M. Verheijen, Ilse Flores, Kayla Love, Ashley Del Dosso, Max A. Thorwald, Yuchen Liu, Daniel Hicks, Yingwo Sun, Renaldo G. Toney, Lucy Carrillo, Megan M. Nguyen, Huang Biao, Yuxin Jin, Ashley Michelle Jauregui, Juan Diaz Quiroz, Elizabeth Head, Darcie L. Moore, Stephen Simpson, Kelley W. Thomas, Marcelo P. Coba, Zhongwei Li, Bérénice A. Benayoun, Joshua J. C. Rosenthal, Scott R. Kennedy, Giorgia Quadrato, Jean-Francois Gout, Lin Chen, Marc Vermulst
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Aging is characterized by the accumulation of proteins that display amyloid-like behavior. However, the molecular mechanisms by which these proteins arise remain unclear. Here, we demonstrate that amyloid-like proteins are produced in a vari
Externí odkaz:
https://doaj.org/article/bc97abb49e574bb98ff14f78f00de4cf
Autor:
Fenne W. M. Verheijen, Thi N. M. Tran, Jung‐Chin Chang, Femke Broere, Esther A. Zaal, Celia R. Berkers
Publikováno v:
Molecular Oncology, Vol 18, Iss 7, Pp 1759-1776 (2024)
Metabolism plays a crucial role in regulating the function of immune cells in both health and disease, with altered metabolism contributing to the pathogenesis of cancer and many inflammatory diseases. The local microenvironment has a profound impact
Externí odkaz:
https://doaj.org/article/6e98aaaa530640dd8cf3a64c24ef9490
Autor:
Susan Van Dieren, Joost Nederend, Pieter J Tanis, Roel Hompes, Klaas Havenga, Melissa W Taggart, Robert Riedl, Michail Doukas, Evert-Jan G. Boerma, Marinke Westerterp, Corrie A M Marijnen, Jaap Stoker, Andrew Ruszkiewicz, Tsuyoshi Konishi, Jarno Melenhorst, Karin Muller, Krista Gerbrands, Michael Croft, Michael Wilks, Johanne G. Bloemen, Peter A. Neijenhuis, Koen C.M.J. Peeters, Miranda Kusters, Martijn Intven, Jan Peringa, Maria Verseveld, Eline G M van Geffen, Tania C Sluckin, Sanne-Marije J A Hazen, Karin Horsthuis, Geerard Beets, Marilyne M Lange, Regina G H Beets-Tan, Marc R. W. Engelbrecht, Elisabeth D. Geijsen, Philip Meijnen, Jurriaan B. Tuynman, Ingrid M. Bruijnzeel, Bas Lamme, Femke M. Alberts, Rogier M. P. H. Crolla, Joanne Verdult, Johan H. Wijsman, Charlotte S. van Kessel, Erik Jan Mulder, Jan Binne Hulshoff, Ivan M. Cherepanin, Hans F. J. Fabry, G. Y. Mireille, Frank J. M. Kemper, Fatih Polat, Jacobus W. A. Burger, Jeltsje S. Cnossen, Shira H. de Bie, Robbert J. I. Bosker, Aaldert K. Talsma, Leonora S. F. Boogerd, Marc J. P. M. Govaert, Merel M. Scheurkogel, Imogeen E. Antonisse, Joost Rothbarth, Marianne de Vries, Marcel A. H. Ribbert, Anthony W. H. van de Ven, Susan ter Borg, Jennifer W. Bradshaw, Heleen M. Ceha, Fleur I. de Korte, Andreas W. K. S. Marinelli, Tjeerd S. Aukema, Liselotte W. van Bockel, Aukje A. J. M. van Tilborg, Tom Rozema, Amarins Brandsma, Stefan Hoogendoorn, Saskia R. Offerman, Hanneke Vos, Henderik L. van Westreenen, Jeroen W. A. Leijtens, Fabian A. Holman, Laura A. Velema, L Els, van Persijn van Meerten, Frans C. H. Bakers, Iryna Samarska, Nina Šefčovičová, Maaike Berbée, Bastiaan B. Pultrum, Dennis B. Rouw, Matthew Albert, L. René Arensman, Hanneke Basart, Esther C. J. Consten, Bart C.T. van de Laar, Inne Somers, Paul M. Verheijen, Thomas A. Fassaert, Christiaan Hoff, Eino B. van Duyn, Ellen M. Hendriksen, Hugo A.J. Gielkens, Arend G. J. Aalbers, Brechtje A. Grotenhuis, Michalda S. Dunker, Anne M. van Geel, Christof Meischl, W. Hermien Schreurs, Patty H. Spruit, Michael F. Gerhards, Thomas M. Karsten, Eveline J.T. Krul, Sebastiaan van Koeverden, Andre J. A. Bremers, Heidi Rütten, Johannes H. W. de Wilt, Mariska den Hartogh, Vera Oppedijk, Jan Willem T. Dekker, Debora Eschbach-Zandbergen, Daphne Roos, Arjan van Tilburg, Ernst Jan, Spillenaar Bilgen, Nikki Knijn, Marnix A. J. de Roos, Ilse van Dop, Tracy Fitzsimmons, Hidde M. Kroon, Michael Penniment, Mitchell Raeside, Tarik Sammour, Steven J. Oosterling, Jeroen A. W. Tielbeek, Ronald J. C. L. M. Vuylsteke, Erik J. R. J. van der Hoeven, Anke B. Smits, Anniek H. Boer, Edgar J. B. Furnée, Robbert J. de Haas, Manon N. G. J. A. Braat, Wilhelmina M. U. van Grevenstein, Milan C. Richir, Patricia J. A. M. Brouwers, Tilly Leseman, Eric H. J. Belgers, Jasenko Krdzalic, Roy F. A. Vliegen
Publikováno v:
BMJ Open, Vol 14, Iss 10 (2024)
Introduction Inadequate treatment of enlarged lateral lymph nodes (LLNs) in rectal cancer patients is associated with an increased lateral local recurrence (LLR) risk, despite neoadjuvant treatment and total mesorectal excision (TME) surgery. There i
Externí odkaz:
https://doaj.org/article/340de40a283a4148be1229eb0c6c7cba
The cycad genotoxin methylazoxymethanol, linked to Guam ALS/PDC, induces transcriptional mutagenesis
Autor:
Bert M. Verheijen, Claire Chung, Ben Thompson, Hyunjin Kim, Asa Nakahara, Jasper J. Anink, James D. Mills, NYGC ALS Consortium, Jeong H. Lee, Eleonora Aronica, Kiyomitsu Oyanagi, Akiyoshi Kakita, Jean-Francois Gout, Marc Vermulst
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/30f1759d56f94b6dbc7659c15455ac46
Autor:
Inbal Maniv, Mahasen Sarji, Anwar Bdarneh, Alona Feldman, Roi Ankawa, Elle Koren, Inbar Magid-Gold, Noa Reis, Despina Soteriou, Shiran Salomon-Zimri, Tali Lavy, Ellina Kesselman, Naama Koifman, Thimo Kurz, Oded Kleifeld, Daniel Michaelson, Fred W. van Leeuwen, Bert M. Verheijen, Yaron Fuchs, Michael H. Glickman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Alzheimer’s disease (AD) is characterized by toxic protein accumulation in the brain. Ubiquitination is essential for protein clearance in cells, making altered ubiquitin signaling crucial in AD development. A defective variant, ubiquitin
Externí odkaz:
https://doaj.org/article/74e57d7f81c342d092153d856a153d11
Autor:
Claire Chung, Bert M. Verheijen, Zoe Navapanich, Eric G. McGann, Sarah Shemtov, Guan-Ju Lai, Payal Arora, Atif Towheed, Suraiya Haroon, Agnes Holczbauer, Sharon Chang, Zarko Manojlovic, Stephen Simpson, Kelley W. Thomas, Craig Kaplan, Peter van Hasselt, Marc Timmers, Dorothy Erie, Lin Chen, Jean-Franćois Gout, Marc Vermulst
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
The molecular mechanisms that ensure faithful transcription of genetic information are still unclear. Chung et al. identify various genes, alleles and processes that affect the fidelity of transcription multiple organisms, suggesting evolutionary con
Externí odkaz:
https://doaj.org/article/096147bca5dd41de8f7b050e54beb959
Autor:
Suzy Varderidou-Minasian, Bert M. Verheijen, Oliver Harschnitz, Sandra Kling, Henk Karst, W. Ludo van der Pol, R. Jeroen Pasterkamp, Maarten Altelaar
Publikováno v:
ACS Omega, Vol 6, Iss 51, Pp 35375-35388 (2021)
Externí odkaz:
https://doaj.org/article/e82a0a9c2a524d3fa27fb3e05b82551b
Autor:
Bert M. Verheijen, Aaron Ciechanover
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/f263d679e17a4d8b9816b24f3d5ece19
Autor:
I. Ubink, H. J. Bloemendal, S. G. Elias, M. A. Brink, M. P. Schwartz, Y. C. W. Holierhoek, P. M. Verheijen, A. W. Boerman, R. H. J. Mathijssen, W. W. J. de Leng, R. A. de Weger, W. M. U. van Grevenstein, M. Koopman, M. P. Lolkema, O. Kranenburg, I. H. M. Borel Rinkes
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-7 (2017)
Abstract Background The identification of four Consensus Molecular Subtypes (CMS1–4) of colorectal cancer forms a new paradigm for the design and evaluation of subtype-directed therapeutic strategies. The most aggressive subtype - CMS4 - has the hi
Externí odkaz:
https://doaj.org/article/3d091384b8484855b856fef7efe841d1
Autor:
Thijs A. Burghgraef, Daan J. Sikkenk, Paul M. Verheijen, Mostafa El Moumni, Roel Hompes, Esther C. J. Consten
Publikováno v:
Burghgraef, T A, Sikkenk, D J, Verheijen, P M, Moumni, M E, Hompes, R & Consten, E C J 2022, ' The learning curve of laparoscopic, robot-assisted and transanal total mesorectal excisions : a systematic review ', Surgical Endoscopy, vol. 36, no. 9, pp. 6337-6360 . https://doi.org/10.1007/s00464-022-09087-z
Background The standard treatment of rectal carcinoma is surgical resection according to the total mesorectal excision principle, either by open, laparoscopic, robot-assisted or transanal technique. No clear consensus exists regarding the length of t