Generation of the Fip1l1–Pdgfra fusion gene using CRISPR/Cas genome editing

Autor: Ellen Geerdens, Nicole Mentens, Jan Cools, Sofie Demeyer, Iwona Wlodarska, M. Vanden Bempt, C E de Bock

Publikováno v: Leukemia

ispartof: Leukemia vol:30 issue:9 pages:1913-1916 ispartof: location:England status: published

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55826b4a991c3ad8489d27f0b3b653d7
http://europepmc.org/articles/PMC5240015

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HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development.

Autor: de Bock CE; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Demeyer S; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Degryse S; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Verbeke D; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Sweron B; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Gielen O; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Vandepoel R; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Vicente C; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Vanden Bempt M; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Dagklis A; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Geerdens E; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Bornschein S; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Gijsbers R; Laboratory for Viral Vector Technology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium., Soulier J; U944 INSERM and Hematology Laboratory, St-Louis Hospital, APHP, Hematology University Institute, University Paris-Diderot, Paris, France., Meijerink JP; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands., Heinäniemi M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland., Teppo S; Tampere Centre for Child Health Research, University of Tampere and Tampere University Hospital, Tampere, Finland., Bouvy-Liivrand M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland., Lohi O; Tampere Centre for Child Health Research, University of Tampere and Tampere University Hospital, Tampere, Finland., Radaelli E; KU Leuven, Center for Human Genetics, Leuven, Belgium.; VIB, Center for Cancer Biology, Leuven, Belgium., Cools J; KU Leuven, Center for Human Genetics, Leuven, Belgium. jan.cools@kuleuven.vib.be.; VIB, Center for Cancer Biology, Leuven, Belgium.

Publikováno v: Cancer discovery [Cancer Discov] 2018 May; Vol. 8 (5), pp. 616-631. Date of Electronic Publication: 2018 Mar 01.