Zobrazeno 1 - 10
of 83
pro vyhledávání: '"M. Van Tiel"'
Publikováno v:
Hydrology and Earth System Sciences, Vol 25, Pp 3245-3265 (2021)
Warm and dry summer days can lead to low streamflow due to a lack of rainfall and increased evaporation. In glacierized catchments, however, such periods can lead to a very different hydrological response as glaciers can supply an increased amount of
Externí odkaz:
https://doaj.org/article/830ec8b0b7e9441880467d03c3b0f10b
Publikováno v:
Hydrology and Earth System Sciences, Vol 22, Pp 463-485 (2018)
Glaciers are essential hydrological reservoirs, storing and releasing water at various timescales. Short-term variability in glacier melt is one of the causes of streamflow droughts, here defined as deficiencies from the flow regime. Streamflow dr
Externí odkaz:
https://doaj.org/article/4cfb2bbcb72f4ee797c6e4634fffa585
Autor:
Sanne C. Lith, Tom M.J. Evers, Beatriz M. Freire, Claudia M. van Tiel, Winnie G. Vos, Alireza Mashaghi, Carlie J.M. de Vries
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151419- (2024)
Nuclear receptor Nur77 plays a pivotal role in immune regulation across various tissues, influencing pro-inflammatory signaling pathways and cellular metabolism. While cellular mechanics have been implicated in inflammation, the contribution of Nur77
Externí odkaz:
https://doaj.org/article/5bc64154a48245b5bf39114a50ff526b
Autor:
Winnie G. Vos, Bram W. van Os, Myrthe den Toom, Linda Beckers, Cindy P.A.A. van Roomen, Claudia M. van Tiel, Bhopal C. Mohapatra, Hamid Band, Katrin Nitz, Christian Weber, Dorothee Atzler, Menno P.J. de Winther, Laura A. Bosmans, Esther Lutgens, Tom T.P. Seijkens
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAtherosclerosis is a lipid-driven inflammatory disease of the arterial wall, and the underlying cause of the majority of cardiovascular diseases. Recent advances in high-parametric immunophenotyping of immune cells indicate that T cells c
Externí odkaz:
https://doaj.org/article/17ccf05dbe754c14b60fa4b6e02d7e09
Autor:
Myrthe E. Reiche, Kikkie Poels, Laura A. Bosmans, Winnie G. Vos, Claudia M. van Tiel, Marion J.J. Gijbels, Suzanne A.B.M. Aarts, Myrthe den Toom, Linda Beckers, Christian Weber, Dorothee Atzler, Patrick C.N. Rensen, Sander Kooijman, Esther Lutgens
Publikováno v:
Haematologica, Vol 108, Iss 7 (2022)
The co-stimulatory CD40-CD40L dyad plays an important role in chronic inflammatory diseases associated with aging. Although CD40 is mainly expressed by immune cells, CD40 is also present on adipocytes. We aimed to delineate the role of adipocyte CD40
Externí odkaz:
https://doaj.org/article/481a8be17f204ccbab4fa7b1713b7c52
Autor:
Bram W. van Os, Pascal J. H. Kusters, Myrthe den Toom, Linda Beckers, Claudia M. van Tiel, Winnie G. Vos, Elize de Jong, Arnd Kieser, Cindy van Roomen, Christoph J. Binder, Myrthe E. Reiche, Menno P. de Winther, Laura A. Bosmans, Esther Lutgens
Publikováno v:
Frontiers in Cardiovascular Medicine. 10
BackgroundAtherosclerosis is the underlying cause of many cardiovascular diseases, such as myocardial infarction or stroke. B cells, and their production of pro- and anti-atherogenic antibodies, play an important role in atherosclerosis. In B cells,
Autor:
Laura A Bosmans, Claudia M van Tiel, Suzanne A B M Aarts, Lisa Willemsen, Jeroen Baardman, Bram W van Os, Myrthe den Toom, Linda Beckers, David J Ahern, Johannes H M Levels, Aldo Jongejan, Perry D Moerland, Sanne G S Verberk, Jan van den Bossche, Menno M P J de Winther, Christian Weber, Dorothee Atzler, Claudia Monaco, Norbert Gerdes, Annelie Shami, Esther Lutgens
Publikováno v:
Cardiovascular Research, 119(5), 1146-1160. Oxford University Press
Cardiovascular research. Oxford University Press
Cardiovascular research. Oxford University Press
Aims:CD40 and its ligand, CD40L, play a critical role in driving atherosclerotic plaque development. Disrupted CD40-signalling reduces experimental atherosclerosis and induces a favourable stable plaque phenotype. We recently showed that small molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44da9195cce2f5744715e6be73ea41d8
https://doi.org/10.1093/cvr/cvac084
https://doi.org/10.1093/cvr/cvac084
Autor:
Bram W van Os, Winnie G Vos, Laura A Bosmans, Claudia M van Tiel, Sanne C Lith, Myrthe S den Toom, Linda Beckers, Johannes H M Levels, Suzanne A E van Wouw, Noam Zelcer, Esther A Zaal, Celia R Berkers, Chris H A van der Lest, J Bernd Helms, Christian Weber, Dorothee Atzler, Menno P J de Winther, Jeroen Baardman, Esther Lutgens
Publikováno v:
European Heart Journal Open. 3
AimsHyperlipidemia and T cell driven inflammation are important drivers of atherosclerosis, the main underlying cause of cardiovascular disease. Here, we detailed the effects of hyperlipidemia on T cells.Methods and resultsIn vitro, exposure of human
Autor:
Pascal J. H. Kusters, Ela Karshovka, Johan W. M. Heemskerk, Norbert Gerdes, Esther Lutgens, Annelie Shami, Sigrid Unterlugauer, Myrthe E. Reiche, Christian Weber, Christina Bürger, Maiwand Ahmadsei, Tom Seijkens, Isabel Gonçalves, Sanne L. N. Brouns, Michael Lacy, Katrin Nitz, Holger Winkels, Claudia M. van Tiel, Dorothee Atzler, Yuting Wu, Marijke J.E. Kuijpers, Remco T. A. Megens, Sabine Steffens, Koen H.M. Prange, Andreas Edsfeldt
Publikováno v:
Nature communications, 12(1):3754. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications, 12(1):3754. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications, 12(1):3754. Nature Publishing Group
Atherosclerosis is a major underlying cause of cardiovascular disease. Previous studies showed that inhibition of the co-stimulatory CD40 ligand (CD40L)-CD40 signaling axis profoundly attenuates atherosclerosis. As CD40L exerts multiple functions dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6b2e53b5c95a4b1ff46770600637b3
https://pure.amc.nl/en/publications/cellspecific-and-divergent-roles-of-the-cd40lcd40-axis-in-atherosclerotic-vascular-disease(eb2da2f3-77ab-4b81-9e0f-a30959e5ccc4).html
https://pure.amc.nl/en/publications/cellspecific-and-divergent-roles-of-the-cd40lcd40-axis-in-atherosclerotic-vascular-disease(eb2da2f3-77ab-4b81-9e0f-a30959e5ccc4).html
Autor:
Matthijs S Ruiter, Claudia M van Tiel, Albert Doornbos, Goran Marinković, Aart C Strang, Nico J M Attevelt, Vivian de Waard, Robbert J de Winter, Rob Steendam, Carlie J M de Vries
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138459 (2015)
The introduction of drug-eluting stents (DES) has dramatically reduced restenosis rates compared with bare metal stents, but in-stent thrombosis remains a safety concern, necessitating prolonged dual anti-platelet therapy. The drug 6-Mercaptopurine (
Externí odkaz:
https://doaj.org/article/03a0521f57254233ae1b676b203c4f4f