Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M. Van Gucht"'
Autor:
Anne H van der Spek, Olga V Surovtseva, Saskia Aan, Anton T J Tool, Annemarie van de Geer, Korcan Demir, Anja L M van Gucht, A S Paul van Trotsenburg, Timo K van den Berg
Publikováno v:
Endocrine Connections, Vol 6, Iss 8, Pp 731-740 (2017)
Innate immune cells have recently been identified as novel thyroid hormone (TH) target cells in which intracellular TH levels appear to play an important functional role. The possible involvement of TH receptor alpha (TRα), which is the predominant
Externí odkaz:
https://doaj.org/article/a8ac5142194546998f6b57a9c79396df
Autor:
W. Edward Visser, Robin P. Peeters, Anja L M van Gucht, Karn Wejaphikul, Stefan Groeneweg, Marcel E Meima, Theo J. Visser
Publikováno v:
Thyroid, 29(12), 1834-1842. Mary Ann Liebert Inc.
Background: Thyroid hormone (TH) acts on TH receptors (TRs) and regulates gene transcription by binding of TRs to TH response elements (TREs) in target gene promoters. The transcriptional activity of TRs is modulated by interactions with TR-coregulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0c30892047053484638d045876174a
https://doi.org/10.1089/thy.2019.0019
https://doi.org/10.1089/thy.2019.0019
Autor:
Karn, Wejaphikul, Anja L M, van Gucht, Stefan, Groeneweg, W Edward, Visser, Theo J, Visser, Robin P, Peeters, Marcel E, Meima
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 29(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fcd32a5f5a4dcbf104547206ddc27e5
https://pubmed.ncbi.nlm.nih.gov/31530256
https://pubmed.ncbi.nlm.nih.gov/31530256
Autor:
Anja L M van Gucht, W. Edward Visser, Theo J. Visser, Robin P. Peeters, Alies A.A. van Mullem, Marcel E Meima
Publikováno v:
Molecular and Cellular Endocrinology, 437(C), 252-260. Elsevier Ireland Ltd
Transport of thyroid hormone (TH) across the plasma membrane is necessary for the genomic action of T3 mediated by its nuclear T3 receptor. MCT8 and MCT10 have been identified as important TH transporters. Mutations in MCT8 result in severe psychomot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725b5f134179bfe34f12c169481a991e
https://hdl.handle.net/1765/97359
https://hdl.handle.net/1765/97359
Autor:
Anja L M, van Gucht, Carla, Moran, Marcel E, Meima, W Edward, Visser, Krishna, Chatterjee, Theo J, Visser, Robin P, Peeters
Publikováno v:
Current topics in developmental biology. 125
Thyroid hormone (TH) acts via nuclear thyroid hormone receptors (TRs). TR isoforms (TRα1, TRα2, TRβ1, TRβ2) are encoded by distinct genes (THRA and THRB) and show differing tissue distributions. Patients with mutations in THRB, exhibiting resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfbdd21cad2b657228c8419eef87eed4
https://pubmed.ncbi.nlm.nih.gov/28527577
https://pubmed.ncbi.nlm.nih.gov/28527577
Autor:
Carla Moran, Robin P. Peeters, Marcel E Meima, Anja L M van Gucht, Krishna Chatterjee, W. Edward Visser, Theo J. Visser
Background: Thyroid hormone (TH) acts via nuclear thyroid hormone receptors (TRs). TR isoforms (TRα1, TRα2, TRβ1, TRβ2) are encoded by distinct genes (THRA and THRB) and show differing tissue distributions. Patients with mutations in THRB, exhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5f1bfec5d0a42cb16acebafe863a8b5
https://doi.org/10.1016/bs.ctdb.2017.02.001
https://doi.org/10.1016/bs.ctdb.2017.02.001
Autor:
Joanne M. Donkers, Alies A.A. van Mullem, Anja L M van Gucht, Giulia Brigante, Theo J. Visser, Simone Kersseboom, Stan F.J. van de Graaf, Bo Carlsson, Stefania Farina, Robin P. Peeters
Publikováno v:
Endocrinology, 158(10), 3307-3318. The Endocrine Society
Endocrinology, 158(10), 3307-3318. Endocrine Society
Endocrinology, 158(10), 3307-3318. Endocrine Society
The thyroid hormone (TH) analog eprotirome (KB2115) was developed to lower cholesterol through selective activation of the TH receptor (TR) β1 in the liver. Interestingly, eprotirome shows low uptake in nonhepatic tissues, explaining its lipid-lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b972e0648dc84893c2c4e59e3be9ddc
https://pure.amc.nl/en/publications/role-of-the-bile-acid-transporter-slc10a1-in-liver-targeting-of-the-lipidlowering-thyroid-hormone-analog-eprotirome(661bf35f-8148-487e-970f-00eb1d3c0cff).html
https://pure.amc.nl/en/publications/role-of-the-bile-acid-transporter-slc10a1-in-liver-targeting-of-the-lipidlowering-thyroid-hormone-analog-eprotirome(661bf35f-8148-487e-970f-00eb1d3c0cff).html
Autor:
Robin P. Peeters, Bumin Dündar, W. Edward Visser, Marcel E Meima, Anja L M van Gucht, Yavuz Ayhan, Korcan Demir, Theo J. Visser, Behzat Özkan, Gönül Çatlı, Veysel Nijat Baş, Muammer Buyukinan
Publikováno v:
Journal of Clinical Endocrinology and Metabolism, 101(8), 2945-2954. Endocrine Society
Context:Recently several patients with resistance to thyroid hormone (RTH)-α due to T3 receptor-α (TRα) mutations were identified. The phenotype of these patients consists of varying degrees of growth impairment, delayed bone, mental and motor dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5f181104eb79ccc46deab8035e1ee5
https://pubmed.ncbi.nlm.nih.gov/27144938
https://pubmed.ncbi.nlm.nih.gov/27144938
Autor:
Civile Henny, W. Edward Visser, Theo J. Visser, Eric Fliers, Johanna M B Wennink, A S Paul van Trotsenburg, Robin P. Peeters, Nitash Zwaveling-Soonawala, Anja L M van Gucht, Marcel E Meima
Publikováno v:
Thyroid, 26(3), 338-346. Mary Ann Liebert Inc.
Recently, the first patients with resistance to thyroid hormone alpha (RTHα) due to inactivating mutations in the thyroid hormone receptor alpha (TRα) were identified. These patients are characterized by growth retardation, variable motor and cogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1042924ead4a16e688bd319bb19cd47e
https://pure.amc.nl/en/publications/resistance-to-thyroid-hormone-alpha-in-an-18monthold-girl-clinical-therapeutic-and-molecular-characteristics(5137979b-0970-4aa0-afcd-acf83d960de3).html
https://pure.amc.nl/en/publications/resistance-to-thyroid-hormone-alpha-in-an-18monthold-girl-clinical-therapeutic-and-molecular-characteristics(5137979b-0970-4aa0-afcd-acf83d960de3).html
Publikováno v:
Prenatal Diagnosis, 23, 634-639. John Wiley & Sons Ltd.
Objectives A retrospective analysis of the prognostic significance of the lung-to-head ratio (LHR) and other prenatal parameters on the outcome of fetuses with left-sided congenital diaphragmatic hernia (CDH). Methods A total of 26 fetuses with isola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79a553c8884a4f3fd39c68878d858ae
https://doi.org/10.1002/pd.654
https://doi.org/10.1002/pd.654