Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M. V. Zinov'eva"'
Publikováno v:
Molecular Genetics, Microbiology and Virology. 24:61-67
Polyfunctional protein PML contributes significantly to the vital activity of the cell. Eleven isoforms of PML differ from one another in their C-terminal domain. Despite intensive research into the protein, the role of the isoforms in cellular proce
Autor:
Tatyana V. Vinogradova, Eugene R. Zabarovsky, E. A. Anedchenko, I. B. Zborovskaya, O. V. Sacharova, V. N. Senchenko, E. P. Kopantsev, George S. Krasnov, Vladimir I. Kashuba, B. E. Polotsky, Alexey A. Dmitriev, M. V. Zinov’eva, O. O. Kondrat’eva
Publikováno v:
Molecular Biology. 42:859-869
Chromosomal and genome abnormalities of 3p are frequent in many epithelial tumors, including lung cancer. Several critical regions with a high frequency of hemi-and homozygous deletions in tumors are known for 3p, and more than 20 cancer-related gene
Autor:
Tatyana V. Vinogradova, Igor V. Korobko, M. V. Shepelev, Eugene D. Sverdlov, M. V. Zinov’eva, E. V. Korobko, I. B. Zborovskaya, S. V. Kalinichenko, A. K. Allakhverdiev
Publikováno v:
Molecular Genetics, Microbiology and Virology. 22:53-58
An analysis was made of the change in the expression of the extracellular inhibitor of the Wnt-signal pathway WIF1 in non-small cell lung carcinomas. The results of the analysis revealed a frequent (67% of the cases) suppression of the WIF1 transcrip
Autor:
M. V. Zinov’eva, Eugene D. Sverdlov, Igor V. Korobko, A. K. Allakhverdiev, E. P. Kopantsev, I. B. Zborovskaya
Publikováno v:
Molecular Genetics, Microbiology and Virology. 22:59-63
Changes in the c-Met/HGF system are noted in tumors of various types and may be directly related to their progression. In particular, the c-Met/HGF system may play a definite role in the progression of lung tumors, and changes in the expression of c-
Publikováno v:
Bioorganicheskaia khimiia. 39(6)
In preparation of the therapeutic genetic constructs aimed to the gene-programmed enzymatic transformation of the non-toxic prodrug into toxin within cancer cells the right choice of regulatory elements (promoters and enhancers) is essential. This is
Autor:
Lev L. Kisselev, E. P. Kopantsev, N. Yu. Oparina, A. B. Poltaraus, T. D. Mashkova, M. V. Zinov’eva, I. B. Zborovskaya, E.D. Sverdlov, O. T. Kasymova, Tatyana V. Vinogradova, V. I. Dubovaya, K. K. Laktionov, Zinov'eva Ol, M. V. Fridman, Kropotova Es
Publikováno v:
Molecular Biology. 40:945-951
Lung cancer is among the most common neoplasms in Russia, the United States, and in Western Europe and is accompanied by changes in the functional activity of many genes. The transcription levels of TIMP3, DAPK1, and AKR1B10 were compared for normal
Publikováno v:
Molekuliarnaia biologiia. 45(3)
Melanoma is one of the most malignant tumors, aggressively metastasizing by lymphatic and hematogenous routes. Due to the resistance of melanoma cells to many types of chemotherapy, this disease causes high mortality rate. High hopes are pinned on ge
Autor:
A V, Kudriavtseva, E A, Anedchenko, N Iu, Oparina, G S, Krasnov, K N, Kashkin, A A, Dmitriev, I B, Zborobskaia, T T, Kondtrat'eva, T V, Vinogradova, E V, Vinogradova, M V, Zinov'eva, E P, Kopantsev, V N, Senchenko
Publikováno v:
Molekuliarnaia biologiia. 43(6)
The level of ferritin in serum is known to be increased frequently in most human cancers. Ferritin consists of the heavy and light chains, encoded by FTL and FTH genes. The analysis of the EST database showed that the level of FTL and FTH mRNA is dec
Publikováno v:
Molekuliarnaia genetika, mikrobiologiia i virusologiia. (2)
Polyfunctional protein PML contributes significantly in vital activity of cell. 11 isoforms of PML differ from one another by C-terminal domain. In spite of intensive research into the protein, the role of the isoforms in cellular processes remains o
Publikováno v:
Molekuliarnaia biologiia. 42(4)
Survivin (BIRC5) is one of the members of IAP-family apoptosis inhibitors. The BIRCS gene is expressed in most human embryonic tissues and malignant tumors but not in normal differentiated tissues of adult human. It was suggested that BIRC5 proteins